Search results for "ALLOYS"
showing 10 items of 1689 documents
X-ray crystallography-promoted drug design of carbonic anhydrase inhibitors.
2015
1-N-Alkylated-6-sulfamoyl saccharin derivatives were prepared and assayed as carbonic anhydrase inhibitors (CAIs). During X-ray crystallographic experiments an unexpected hydrolysis of the isothiazole ring was evidenced which allowed us to prepare highly potent enzyme inhibitors with selectivity for some isoforms with medical applications.
Chemical and biological evaluation of cross-linked halloysite-curcumin derivatives
2020
Abstract Well designed and safe nano drug carrier systems are an important tool in biomedical applications. The combination of two or more drugs has been used in medicine both to enhance the therapeutic effect and to decrease the side effects of drugs. Biocompatible halloysite nanotubes, that possess two different surfaces, are a suitable nanomaterial for a simultaneous carrier and release of two drugs that can exert a synergistic effect against cancer cells. In this study, three curcumin derivatives and doxorubicin were loaded by supramolecular and covalent linkage at the lumen and external surface of the halloysite nanotubes. The obtained multifunctional systems were characterized by seve…
Electrochemical synthesis of benzoxazoles from anilides - a new approach to employ amidyl radical intermediates.
2017
A novel electrochemical method for the synthesis of benzoxazoles from readily available anilides is reported. Various functionalities are tolerated and good yields can be achieved. By employing common electrode materials and a simple constant current protocol, this method is an attractive new alternative to conventional pathways.
Simple and scalable electrochemical synthesis of 2,1-benzisoxazoles and quinoline N-oxides.
2019
Cathodic reduction of the nitro moiety and subsequent intramolecular cyclization affords different substituted 2,1-benzisoxazoles and quinoline N-oxides. This methodology allows the synthesis of two different types of heterocycles from common simple starting materials, using electrons as a sole reagent for this transformation. The electrolysis can be conducted in a very simple undivided electrolysis cell under constant current conditions. This permits working on a larger scale compared to other electrochemical methodologies and represents a significant advantage.
The effect of hydration layers on the anodic growth and on the dielectric properties of Al2O3 for electrolytic capacitors
2014
Hydrous films were grown on high purity and cubicity Al foils for electrolytic capacitors in deionized water, ethylene glycol - deionized water and in glycerol - deionized water for different immersion times. According to the X-ray diffraction patterns the hydration treatment allowed to grow a pseudo boehmite layer on Al surface whose morphology is appreciably affected by the bath composition. Capacitance measurements and photoelectrochemical findings suggest that a more compact barrier layer forms during the immersion in alcohol containing solutions. The hydration in water allowed to save energy and to prepare more blocking oxide films. The beneficial effect of hydration in hot water on th…
High-pressure optical absorption in InN: Electron density dependence in the wurtzite phase and reevaluation of the indirect band gap of rocksalt InN
2012
We report on high-pressure optical absorption measurements on InN epilayers with a range of free-electron concentrations (5×1017–1.6×1019 cm−3) to investigate the effect of free carriers on the pressure coefficient of the optical band gap of wurtzite InN. With increasing carrier concentration, we observe a decrease of the absolute value of the optical band gap pressure coefficient of wurtzite InN. An analysis of our data based on the k·p model allows us to obtain a pressure coefficient of 32 meV/GPa for the fundamental band gap of intrinsic wurtzite InN. Optical absorption measurements on a 5.7-μm-thick InN epilayer at pressures above the wurtzite-to-rocksalt transition have allowed us to o…
The resistivity and thermopower of amorphous Mg-Zn alloys
1983
The resistivity and thermopower of amorphous Mg-Zn alloys have been computed as a function of temperature and composition. The diffraction model incorporating the dynamical partial structure factors is applied. The effect of the electron mean free path is investigated. The authors find that the resistivity is well described by the model, and that the inclusion of the mean free path does not change the results considerably. In the case of thermopower the diffraction model turns out to be inadequate: it gives a composition dependence which is against the experimental evidence. This suggests that there exists another scattering mechanism, which is not accounted for by the diffraction model. Th…
Biomimetic oxidation of pyrene and related aromatic hydrocarbons. Unexpected electron accepting abilities of pyrenequinones
2014
We present a mild catalytic method to oxidize PAHs and, in particular, pyrene. The pyrenediones are much better electron acceptors than benzoquinone in the gas phase and present similar accepting abilities in solution.
Part program automatic check for three axis CNC machines
2001
Abstract The simulation and verification of NC codes for CNC machining is a very important task. The aim of this work is to limit the number of cutting tests needed to verify the right writing of the part program for a CN milling machine in the intent of saving time, human resources and money. This is obtained through the Boolean operation among solids, in AutoCAD environment, of the volume covered by the tool during the operations ruled by the part program.
Finite element modelling of temperature distribution in the cutting zone in turning processes with differently coated tools
2005
Abstract The aim of this study is to check the applicability of various simulation models to obtain finite element solutions of cutting forces, specific cutting energy and adequate temperatures for a range of coated tool materials and defined cutting conditions. Commercial explicit finite element code Thirdwave AdvantEdge has been used in simulations of orthogonal cutting processes performed by means of uncoated carbide and coated tools. The latter were equipped with progressively increasing number of thin layers including TiC, TiN and Al 2 O 3 films deposited onto ISO P20 carbide substrates. Results showing the tool–chip interfacial friction influencing the temperature distribution fields,…