Search results for "AMT"

Determination of triamterene and its main metabolite hydroxytriamterene sulfate in human urine by capillary electrophoresis using ultraviolet absorba…

2002

Abstract Two capillary electrophoresis methods have been developed for the direct determination of triamterene and its main metabolite hydroxytriamterene sulfate in human urine. Analytes were detected using conventional UV detection as well as laser-induced fluorescence (LIF) detection with an HeCd-laser operating at a wavelength of 325 nm. The results of both detection techniques were compared. Indeed, the limit of quantification was eightfold lower using LIF detection (50 ng/ml) in comparison to UV detection (400 ng/ml). As no interference due to endogenous urine compounds was observed, direct urine analysis was feasible. Analysis was very simple and fast—one run could be performed within…

Gedenkschrift zum 25-jährigen Jubiläum des Architektenvereins zu Riga, 1889-1914

1914

Gotiskajā šriftā

Offenes Antwortschreiben an das Stadt-Amt zu Riga

1885

Camtasia Studio, creació d’animacions multimèdia educatives

2009

Camtasia Studio es un programa diseñado para la grabación en pantalla de ordenador y su posterior edición. De esta manera se pueden crear animaciones multimedia con capacidades interactivas de manera sencilla en comparación con los tradicionales editores de vídeo y/o animación. En este artículo se estudian la estructura de este programa y las posibilidades de su aplicación al entorno educativo.

Evaluation of Clotting Factor Concentrates for Treatment of Thrombotic Thrombocytopenic Purpura.

2010

Abstract Abstract 3678 Introduction: Thrombotic thrombocytopenic purpura (TTP) is characterized by microthrombi, hemolytic anemia as well as thrombocytopenia. These symptoms are caused by a decreased activity of the protease ADAMTS13 which cleaves the von Willebrand Factor (VWF), due to mutation of the ADAMTS13-gene or autoantibodies. At the moment, the only available immediate therapy is plasmapheresis with Fresh Frozen Plasma (FFP) which may induce side effects. Therefore an alternative therapy might be the treatment with clotting factor concentrates. Methods: 40 plasma samples were tested, consisting of FFP and solvent/detergent treated plasma, four batches of each blood group; VWF/VIII …

Samtidskunst i skolen : En studie som inviterer elever til en konseptuell workshopspraksis

2019

Masteroppgave kunstfag KF500 - Universitetet i Agder 2019 Both from the elementary school education and the professional life, I have gained insight and an experience basis for commenting on the subject of arts and crafts. There are often techniques and crafts that are in focus. I miss howthe subject to a greater extentcanchallengestudent`s in critical thinking, playful exploration and reflection, especially with regards to visual art. This master thesis focuses on theseperspectives for teaching in the subject arts and crafts, and discuss contemporary art's place intheschool. The thesis can be viewed as a post in the discourse about the new curriculumforarts and crafts, scheduledtobe comple…

Simple and sensitive reversed-phase liquid chromatographic assay for analysis of chlorthalidone in urine

1993

Abstract This study describes a rapid method for the determination of chlorthalidone in human urine by reversed-phase liquid chromatography and UV detection at 230 nm, after clean-up over a C8 solid-phase extraction column. Liquid chromatography was carried out on a C18-bonded phase using acetonitrile-phosphate buffer (pH=3) gradient elution. Triamterene was used as internal standard. The system has been applied to the determination of chlorthalidone in the 0.10–10.0 μg/mL concentration interval; the limit of detection was 6 ng/mL.

Factors Associated with Mortality in Patients Experiencing First Episodes of Acquired Thrombotic Thrombocytopenic Purpura (aTTP). Results of the Span…

2019

Introduction: Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, but life-threatening, hematological disorder characterized by severe thrombocytopenia, hemolytic microangiopathic anemia, and frequent organ damage. The underlying pathophysiology of aTTP is a functional deficiency of plasma ADAMTS13 activity caused by antibodies directed against the ADAMTS13 protease. Despite plasma exchange (PEX) and immunosuppression with corticosteroids, and, more recently, rituximab, which achieve remission in most patients with aTTP, 10-20% of patients are refractory to treatment and die as a result of disease progression. Most of such deaths occur during first episodes of aTTP, as subsequent…

Atypical presentations of thrombotic thrombocytopenic purpura in middle-aged women with recurrent cerebral macrovascular thrombosis: a case report

2015

Dear Editor, In the current clinical practice, minimal criteria to define thrombotic thrombocytopenic purpura (TTP) are the presence of signs of microangiopathic haemolytic anaemia and low platelet (PLT) count [1]. TTP relapses (20–50 % of cases) are defined as the recurrence of acute TTP symptoms 30 days after the first episode, while exacerbations occur within 30 days [2]. We here report on an atypical case of acquired TTP where minimal criteria were met only after many recurrent macrovascular ischemic events. A 42-year old Caucasian woman with a history of coronary and cerebral ischemic events was admitted on June 2013, following a recurrent transient ischemic attack (TIA). She had sever…

ADAMTS13 In 4 Different VWF/VIII Concentrates and Its Impact on Therapy.

2010

Abstract Abstract 3677 Introduction: The hemostatic activity of von Willebrand Factor (VWF) is mainly controlled by the plasma metalloprotease ADAMTS13, which cleaves ultralarge VWF multimers. A qualitative or quantitative deficiency of VWF induces the most common hemorrhagic diathesis, the von Willebrand Disease (VWD). The current classification graduates the VWD in three major types. Depending on severity and the type of VWD the treatment with VWF/FVIII concentrates may by necessary. The commercially available VWF/FVIII concentrates differ in their multimer structure and furthermore also in their pharmacokinetics. We investigated commercial VWF concentrates with respect to their ADAMTS 13…