Search results for "ANN"

Hybrid GMP–polyamine hydrogels as new biocompatible materials for drug encapsulation

2020

Here we present the preparation and characterization of new biocompatible materials for drug encapsulation. These new gels are based on positively charged [1+1] 1H-pyrazole-based azamacrocycles which minimise the electrostatic repulsions between the negatively charged GMP molecules. Rheological measurements confirm the electroneutral hydrogel structure as the most stable for all the GMP-polyamine systems. Nuclear magnetic resonance (NMR) was employed to investigate the kinetics of the hydrogel formation and cryo-scanning electron microscopy (cryo-SEM) was used to obtain information about the hydrogel morphology, which exhibited a non-homogeneous structure with a high degree of cross-linking…

Asymmetric Vinylogous Mannich-Type Addition of α,α-Dicyanoalkenes to α-Fluoroalkyl Sulfinyl Imines

2018

Abstract. The asymmetric vinylogous Mannich reaction (AVMR) of alfa,alfa-dicyanoalkenes with alfa-fluoroalkyl sulfinyl imines has been successfully accomplished. This transformation is unprecedented with fluorinated imines at the same time as the use of dicyanoalkenes in AVMR has been scarcely reported. Several fluorinated sulfinyl imines are compatible with the process, which gaves access to a family of chiral fluorinated amines with excellent level of stereocontrol. Interestingly, the selectivity found in our protocol is reverse to that encountered in analogous AVMR previously reported. Additionally, the synthetic applicability of the addition products has been exemplified with several tr…

Organocatalytic Asymmetric Synthesis of 2,3′-Connected Bis-Indolinones by Mannich Reactions of N-Acetylindolin-3-ones with Isatin N-Boc Ketimines

2017

A highly diastereo- and enantioselective Mannich reaction of N-acetylindolin-3-ones with isatin N-Boc ketimines to form 2,3′-connected bis-indolinones is developed employing a low loading of a readily available bifunctional thiourea catalyst. The asymmetric synthesis connects two indolinones via a vic-diamine unit and generates two neighboring stereocenters.

Reactivity of di-n-butyl-dicyclopentadienylzirconium towards amido stabilized stannylenes

2009

Abstract Reaction of Sn[(N(C 6 H 3 i Pr 2 -2,6)(SiMe 3 )] 2 and [{Sn(N(C 6 H 3 i Pr 2 -2,6)(SiMe 3 )(μ-Cl) 2 ] with di- n -butyl-dicyclopentadienylzirconium yielded the trimetallic a carbene-like complex {[(N(C 6 H 3 i Pr 2 -2,6)(SiMe 3 )]( n -Bu)Sn} 2 Cp 2 Zr. The oxidation of {[(N(C 6 H 3 i Pr 2 -2,6)(SiMe 3 )]( n -Bu)Sn} 2 Cp 2 Zr by oxygen gives the five-membered dioxadistannazirconacyclic complex {[(N(C 6 H 3 i Pr 2 -2,6)(SiMe 3 )]( n -Bu)Sn} 2 O 2 Cp 2 Zr.

Budyko’s Based Method for Annual Runoff Characterization across Different Climatic Areas: an Application to United States

2018

Runoff data knowledge is of fundamental importance for a wide range of hydrological, ecological, and socioeconomic applications. The reconstruction of annual runoff is a fundamental task for several activities related to water resources management, especially for ungauged basins. At catchment scales, the Budyko's framework provides an extremely useful and, in some cases, accurate estimation of the long-term partitioning of precipitation into evapotranspiration and runoff as a function of the prevailing climatic conditions. Recently the same long-term partitioning rules have been successfully used to describe water partitioning also at the annual scale and calculate the annual runoff distrib…

Measuring rill erosion using structure from motion: A plot experiment

2017

Abstract In this paper the results of a plot experiment on rill erosion are reported. The rill network, manually incised on the soil and further shaped by a clear inflow discharge, was surveyed using the three-dimensional photo-reconstruction (3D-PR) technique which allows to obtain a digital terrain model (DTM) by a large series of oblique images of the channel from consumer un-calibrated and non-metric cameras. The three-dimensional (3D) DTM and the quasi-tridimensional (2.5D) model were generated by Agisoft Photoscan software. For a single rill channel, the reliability of the 3D image-based ground measurements of morphological and hydraulic variables was positively tested by the correspo…

Fractals and geography

2007

Coastal precipitation regimes in Kenya.

1997

Kenya is under the influence of the seasonal reversal of the Indian ocean monsoons. However, its coastal belt, up to about 50 km inland, exhibits original climatic features. Hierarchical clustering...

Smap-based retrieval of vegetation opacity and albedo

2020

Over land the vegetation canopy affects the microwave brightness temperature by emission, scattering and attenuation of surface soil emission. The questions addressed in this study are: 1) what is the transparency of the vegetation canopy for different biomes around the Globe at the low-frequency L-band?, 2) what is the seasonal amplitude of vegetation microwave optical depth for different biomes?, 3) what is the effective scattering at this frequency for different vegetation types?, 4) what is the impact of imprecise characterization of vegetation microwave properties on retrieval of soil surface conditions? These questions are addressed based on the recently completed one full annual cycl…

LAI, FAPAR and FCOVER ground-truth map creation from FASat-C satellite imagery and in-situ measurements in Chimbarongo, Chile, for satellite products…

2016

[EN] In remote sensing, validation exercises are essential to ensure the quality of the products originated from satellite Earth observations. To assess the measurement uncertainty derived from satellite products, several ground field data from different ecosystems must be available for use. In the same order of importance, it is necessary to define data sampling and up-scaling methodologies to allow a suitable comparison between the ground data and the pixel size of the product. This paper shows the applied methodology used in the FP7 ImagineS project (Implementing Multi-scale Agricultural Indicators Exploiting Sentinels) to validate 10-days global LAI, FAPAR and vegetation cover products …