Search results for "ARTICLES"
showing 10 items of 9626 documents
Charged jet cross sections and properties in proton-proton collisions at $\sqrt{s}=7$ TeV
2015
The differential charged jet cross sections, jet fragmentation distributions, and jet shapes are measured in minimum bias proton-proton collisions at centre-of-mass energy $\sqrt{s}=7$ TeV using the ALICE detector at the LHC. Jets are reconstructed from charged particle momenta in the mid-rapidity region using the sequential recombination $k_{\rm T}$ and anti-$k_{\rm T}$ as well as the SISCone jet finding algorithms with several resolution parameters in the range $R=0.2$ to $0.6$. Differential jet production cross sections measured with the three jet finders are in agreement in the transverse momentum ($p_{\rm T}$) interval $20<p_{\rm T}^{\rm jet,ch}<100$ GeV/$c$. They are also consistent w…
Predicted gamma-ray image of SN 1006 due to inverse Compton emission
2009
We propose a method to synthesize the inverse Compton (IC) gamma-ray image of a supernova remnant starting from the radio (or hard X-ray) map and using results of the spatially resolved X-ray spectral analysis. The method is successfully applied to SN 1006. We found that synthesized IC gamma-ray images of SN 1006 show morphology in nice agreement with that reported by the H.E.S.S. collaboration. The good correlation found between the observed very-high energy gamma-ray and X-ray/radio appearance can be considered as an evidence that the gamma-ray emission of SN 1006 observed by H.E.S.S. is leptonic in origin, though the hadronic origin may not be excluded.
Deep-learning based reconstruction of the shower maximum X max using the water-Cherenkov detectors of the Pierre Auger Observatory
2021
The atmospheric depth of the air shower maximum $X_{\mathrm{max}}$ is an observable commonly used for the determination of the nuclear mass composition of ultra-high energy cosmic rays. Direct measurements of $X_{\mathrm{max}}$ are performed using observations of the longitudinal shower development with fluorescence telescopes. At the same time, several methods have been proposed for an indirect estimation of $X_{\mathrm{max}}$ from the characteristics of the shower particles registered with surface detector arrays. In this paper, we present a deep neural network (DNN) for the estimation of $X_{\mathrm{max}}$. The reconstruction relies on the signals induced by shower particles in the groun…
Polymeric nanoparticles for siRNA delivery: Production and applications
2017
Gene therapy through the use of siRNA and a polymeric carrier are becoming an efficient therapeutic option to conventional pharmaceutical formulations for the treatment of deadly diseases, such as cancer, pulmonary, ocular and neurodegenerative diseases. However, several considerations regarding the stability, formulation, and efficacy have to be faced up until these systems could be considered to be a marketable pharmaceutical products for to extend siRNA application to clinical practice. This review is focused on the key challenges of siRNA therapeutics, with special attention on the faced obstacles and on the formulation-related difficulties, providing a list of requirements needed for o…
Cationic solid lipid nanoparticles complexed with genetic material for liver tumor treatment
2015
Concept Gene therapy is a growing field of medicine with great potential for the treatment of several diseases and it is based on the delivery of nucleic acids (DNA, RNA, etc.,) to specific cells. To achieve their therapeutic effects, the nucleic acids need to cross several biological barriers and be protected from the degradation by nucleases, present in biological fluids and intracellular compartments, to successfully gain access to their intracellular targets. To overcome these hurdles, it is necessary to deliver the genetic material with biocompatible carriers able to facilitate its translocation across the cell membranes and protect it from being degraded while circulating in the blood…
Learning to read for the first time as adult immigrants in Finland : Reviewing pertinent research of low-literate or non-literate learners’ literacy …
2018
Against the backdrop of increasing global humanitarian migration to highly literate countries and the resulting necessity and challenge to provide language and literacy education to non-literate or low-literate adult second language (L2) learners, this article calls for more research on a new population of late literacy learners, particularly in Finland. The article begins by outlining the pressing necessity for research on this special group of L2 learners who has traditionally been ignored by Second Language Acquisition (SLA) research. It will then go on to illuminate essential components of developing reading literacy, drawing on relevant previous research on pre-literates. Further, the …
Luminescence properties induced by sintering of silica nanoparticles
2014
The effect of sintering on the optical properties of silica nanoparticles, a mean diameter of ~14 nm, are investigated by absorption and luminescence experiments. The sintering is induced by a thermal treatment of 1000 °C for 272 hours; after that the sample is transparent, and emits a bright luminescence under UV excitation. Time resolved photoluminescence spectra excited by a tunable laser source allows to evidence four bands around 2.0 eV, 2.4 eV, 2.7 eV and 3.4 eV, peculiar to defects induced by the sintering.
Bright blue emission of synthesized silica nanoparticles conferred by surface defects
2013
Charge Transport Mechanisms in Heavy-Ion Driven Leakage Current in Silicon Carbide Schottky Power Diodes
2016
Under heavy-ion exposure at sufficiently high reverse bias voltages silicon carbide (SiC) Schottky diodes are observed to exhibit gradual increases in leakage current with increasing ion fluence. Heavy-ion exposure alters the overall reverse current-voltage characteristics of these diodes, leaving the forward characteristics practically unchanged. This paper discusses the charge transport mechanisms in the heavy-ion damaged SiC Schottky diodes. A macro model, describing the reverse current-voltage characteristics in the degraded SiC Schottky diodes is proposed. peerReviewed
Wpływ dodatku bioaktywnych mikrocząstek srebra na właściwości użytkowe tynków mineralnych
2013
Aktywność mikroorganizmów, a przede wszystkim bakterii i grzybów w istotny sposób wpływa na swoiste cechy i wartość użytkową materiałów budowlanych. Jest to rodzaj korozji biologicznej, stanowiącej szczególny przypadek korozji chemicznej, która powoduje obniżenie lub utratę właściwości użytkowych materiału. Oprócz korozji biologicznej, grzyby mogą również stwarzać zagrożenie dla zdrowia użytkowników zasiedlonych obiektów. Ich toksyczne oddziaływanie na zdrowie ludzi i zwierząt uważa się za znacznie groźniejsze w skutkach od biokorozji materiałów. Stosowane obecnie środki biobójcze w postaci biocydów i nanocząstek srebra również mogą stanowić zagrożenie. W prezentowanej pracy przedstawiono w…