Search results for "ASSOCIATION"

Sex Differences in the Physiological Network of Healthy Young Subjects

2021

Within human physiology, systemic interactions couple physiological variables to maintain homeostasis. These interactions change according to health status and are modified by factors such as age and sex. For several physiological processes, sex-based distinctions in normal physiology are present and defined in isolation. However, new methodologies are indispensable to analyze system-wide properties and interactions with the objective of exploring differences between sexes. Here we propose a new method to construct complex inferential networks from a normalization using the clinical criteria for health of physiological variables, and the correlations between anthropometric and blood tests b…

The Impact of Adolescent Internet Addiction on Sexual Online Victimization: The Mediating Effects of Sexting and Body Self-Esteem

2021

Adolescents’ problematic use of the internet and the risk of sexual online victimization are an increasing concern among families, researchers, professionals and society. This study aimed to analyze the interplay between adolescents’ addiction to social networks and internet, body self-esteem and sexual–erotic risk behavior online: sexting, sextortion and grooming. While sexting refers to the voluntary engagement in texting sexual–erotic messages, sextortion and grooming are means of sexual–erotic victimization through the use of the internet. Participants were 1763 adolescents (51% girls), aged 12 to 16 years (M = 14.56

Genomic diversity and population structure analysis reveal few genetic differences among Ethiopian indigenous sheep populations

2017

African sheep, like other domestic sheep, are domesticated from the Asiatic mouflon (Ovis orientalis). They entered the continent through the North and the Horn of Africa regions following maritime and terrestrial trading routes. Ethiopia is one of the main entry points of various plant and animal domesticates into Africa. It is characterised by diverse agro-ecologies, ancient human ethnic diversity and the presence of indigenous sheep breeds/populations of unprecedented morphological diversity (e.g. tail types). Here, we investigate the genome diversity and population structure of 146 unrelated animals from 11 Ethiopian indigenous sheep populations. DNA was extracted from ear tissue punche…

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

2013

Journal article Breast cancer is the most common cancer among women. Common variants at 27 loci have been identified as associated with susceptibility to breast cancer, and these account for ~9% of the familial risk of the disease. We report here a meta-analysis of 9 genome-wide association studies, including 10,052 breast cancer cases and 12,575 controls of European ancestry, from which we selected 29,807 SNPs for further genotyping. These SNPs were genotyped in 45,290 cases and 41,880 controls of European ancestry from 41 studies in the Breast Cancer Association Consortium (BCAC). The SNPs were genotyped as part of a collaborative genotyping experiment involving four consortia (Collaborat…

Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry

2009

We conducted meta-analyses of genome-wide association studies (GWAS) for atrial fibrillation (AF) in participants from five community-based cohorts. Meta-analyses of 896 prevalent (15,768 referents) and 2,517 incident (21,337 referents) AF cases identified a novel locus for AF (ZFHX3, rs2106261, risk ratio [RR]=1.19; P=2.3×10−7), an association that was replicated in the German AF Network (odds ratio=1.44; P=1.6×10−11). Combining the discovery and replication results, rs2106261 was significantly associated with AF (RR=1.25; P=1.8×10−15).

Do social networks bridge political divides? The analysis of VKontakte social network communication in Ukraine

2014

New electronic forms of political communication have become increasingly popular in countries with weak democratic institutions. The effectiveness of these new forms of association in altering political behavior, however, remains uncertain even in developed democratic regimes. This paper investigates connections between regional variation in electoral behavior and regional distribution of electronic social networks in the case of Ukraine's polarized and institutionally unstable democracy. Our analysis of online networks shows that, somewhat contrary to conventional wisdom, electronic communication does not bridge political divides. This finding casts doubt on the effectiveness of online for…

Prediction of User-Brand Associations Based on Sentiment Analysis

2023

Finding the right users to be chosen as targets for advertising campaigns is not a trivial task, and it may allow important commercial advantages. A novel approach is presented here for the recommendation of new possible consumers to brands interested in distributing advertising campaigns, ranked according to the “compatibility” between users and brands. A database containing both descriptions associated with different brands, and textual information about users' opinions on different topics, is required in input. Then, sentiment analysis techniques are applied to measure to what extent the users match with the brands, based on the texts associated with their opinions. The approach has been…

Combined Use of Structure Analysis, Studies of Molecular Association in Solution, and Molecular Modelling to Understand the Different Propensities of…

2021

The arrangement of hydroxyl groups in the benzene ring has a significant effect on the propensity of dihydroxybenzoic acids (diOHBAs) to form different solid phases when crystallized from solution. All six diOHBAs were categorized into distinctive groups according to the solid phases obtained when crystallized from selected solvents. A combined study using crystal structure and molecule electrostatic potential surface analysis, as well as an exploration of molecular association in solution using spectroscopic methods and molecular dynamics simulations were used to determine the possible mechanism of how the location of the phenolic hydroxyl groups affect the diversity of solid phases formed…

Models and methods for space and space-time interactions in complex point processes with applications on earthquakes

The Far-Reaching Consequences of Job Insecurity : A Review on Family-Related Outcomes

2017

Job insecurity (JI) appears a fairly stable job stressor in working life today and likely to impair employee well-being. This review article presents the key findings of studies examining the effects of perceived JI on family well-being (e.g., marital/parental role quality, work–family conflict). The results, based on 25 published peer-reviewed studies, suggest an association between JI and impaired family well-being. Thus, JI spills over into family life as proposed in the spillover theory of work–family interface. Furthermore, studies have found some evidence of crossover effects of JI from parents to children: parents’ JI relates to negative outcomes in children. These results support th…