Search results for "ASTER"

showing 10 items of 2223 documents

Unprecedented new nonadecylpara-hydroperoxycinnamate isolated fromErythrina excelsaand its cytotoxic activity

2014

A new unprecedented cinnamate derivative (1) was obtained from Erythrina excelsa (Leguminosae) and identified as nonadecyl para-hydroperoxycinnamate. This compound was isolated together with three known compounds, namely lupeol (2), mixture of sitosterol and stigmasterol (3), and isoneorautenol (4). Their structures were established on the basis of NMR and mass spectroscopic data in conjunction with those reported in the literature. Compound 1 was evaluated for its capability of inhibiting cancer cell lines and growth of a panel of microbial strains. It turned out that 1 is moderately to significantly cytotoxic against six cancer cell lines and shows weak to no antimicrobial activity.

Magnetic Resonance SpectroscopyStereochemistryPlant ScienceBiochemistryMass SpectrometryAnalytical Chemistrychemistry.chemical_compoundCell Line TumorHumansIsoneorautenolCytotoxic T cellErythrinaErythrinaLupeolStigmasterolMolecular StructurebiologyPlant ExtractsOrganic ChemistryFabaceaeAntimicrobialbiology.organism_classificationAntineoplastic Agents PhytogenicAnti-Bacterial AgentschemistryCinnamatesPlant BarkDrug Screening Assays AntitumorDerivative (chemistry)Natural Product Research
researchProduct

A model species for agricultural pest genomics: the genome of the Colorado potato beetle, Leptinotarsa decemlineata (Coleoptera: Chrysomelidae)

2018

AbstractThe Colorado potato beetle is one of the most challenging agricultural pests to manage. It has shown a spectacular ability to adapt to a variety of solanaceaeous plants and variable climates during its global invasion, and, notably, to rapidly evolve insecticide resistance. To examine evidence of rapid evolutionary change, and to understand the genetic basis of herbivory and insecticide resistance, we tested for structural and functional genomic changes relative to other arthropod species using genome sequencing, transcriptomics, and community annotation. Two factors that might facilitate rapid evolutionary change include transposable elements, which comprise at least 17% of the gen…

Male0106 biological sciences0301 basic medicineGenome Insectlcsh:Medicine01 natural sciencesGenomeNucleotide diversityInsecticide Resistancepomme de terreTRIBOLIUM-CASTANEUMlcsh:ScienceLeptinotarsaCYSTEINE PROTEINASESPhylogeny2. Zero hungereducation.field_of_studyGenomeMultidisciplinarybiologyinsecte ravageurEcologyGenètica vegetalAgricultureleptinotarsa decemlineataGenomicsS-TRANSFERASE GENESlutte contre les ravageursColeopteraOther Physical Sciencesphénotypeespèce modèleMultigene FamilyInsect ProteinsRNA InterferenceFemaleBiotechnologyAutre (Sciences du Vivant)Genome evolutiondoryphorecoleopteraEvolutionPopulationPopulationRNA-INTERFERENCEGenomicsGEOGRAPHIC POPULATIONSArticleDNA sequencingHost-Parasite InteractionsEvolution Molecular03 medical and health sciences[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]GeneticsAnimalsanalyse génomiquePest Control BiologicaleducationQH426GeneSolanum tuberosumComparative genomicsbusiness.industrychrysomelidaelcsh:RHuman GenomefungiColorado potato beetlePest controlBiology and Life SciencesMolecularGenetic VariationMolecular Sequence AnnotationBiologicalbiology.organism_classification010602 entomologyGenòmicaGenetics Population030104 developmental biologyGene Expression RegulationDROSOPHILA-MELANOGASTERPROTEINASE-INHIBITORSEvolutionary biologyTRANSPOSABLE ELEMENTSDNA Transposable Elementslcsh:QPest ControlBiochemistry and Cell BiologyPEST analysisCAENORHABDITIS-ELEGANSbusinessInsectTranscription Factors
researchProduct

Mapping candidate genes for Drosophila melanogaster resistance to the parasitoid wasp Leptopilina boulardi.

2006

Drosophila melanogaster resistance against the parasitoid wasp Leptopilina boulardi is under the control of a single gene (Rlb), with two alleles, the resistant one being dominant. Using strains bearing deletions, we previously demonstrated that the 55E2–E6; 55F3 region on chromosome 2R is involved in the resistance phenomenon. In this paper, we first restricted the Rlb containing region by mapping at the molecular level the breakpoints of the Df(2R)Pc66, Df(2R)P34 and Df(2R)Pc4 deficiencies, using both chromosomal in situ hybridization and Southern analyses. The resistance gene was localized in a 100 kb fragment, predicted to contain about 10 different genes. Male recombination genetic exp…

Male0106 biological sciencesCandidate geneWaspsGenes Insect010603 evolutionary biology01 natural sciencesParasitoid wasp03 medical and health sciencesGenes RegulatorGeneticsAnimalsDrosophila Proteins[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyAlleleGeneIn Situ Hybridization030304 developmental biologyRecombination GeneticGenetics0303 health sciences[SDV.GEN]Life Sciences [q-bio]/GeneticsModels GeneticbiologyBreakpointIntracellular Signaling Peptides and ProteinsChromosome MappingMembrane ProteinsChromosomeGeneral MedicineCosmidsbiology.organism_classificationDrosophila melanogasterLarvaDrosophila melanogasterRecombination
researchProduct

Temperature affects the ontogeny of sexually dimorphic cuticular hydrocarbons inDrosophila melanogaster

2002

0022-0949 (Print) Journal Article Research Support, Non-U.S. Gov't; Hydrocarbons on the cuticle of mature Drosophila melanogaster flies play a crucial role in mate recognition, and protect against dehydration. We measured the effect of temperature on mature cuticular hydrocarbons (CHs) by (i) rearing two control strains at different temperatures, (ii) shifting the temperature after metamorphosis and (iii) inducing a single heat-shock pulse in control and heat-sensitive transgenic strains, over a period of 3 days following adult eclosion. This study describes the time course of the events involved in the production of male- and female-predominant CHs. We also found that 'immature' CHs, sexua…

Male0106 biological sciencesHot TemperaturePhysiologyOntogenymedia_common.quotation_subjectPeriod (gene)CuticleTransgeneZoologyGenetically ModifiedHydrocarbons/analysis/*metabolismAquatic Science010603 evolutionary biology01 natural sciencesAnimals Genetically Modified03 medical and health sciencesBotanyAnimalsMetamorphosisMolecular BiologyEcology Evolution Behavior and Systematics030304 developmental biologymedia_commonSex Characteristics0303 health sciencesintegumentary systembiologyfungibiology.organism_classificationHeatHydrocarbonsSexual dimorphismKineticsDrosophila melanogasterInsect ScienceTime courseDrosophila melanogaster/*growth & development/metabolismFemaleAnimal Science and ZoologyDrosophila melanogasterJournal of Experimental Biology
researchProduct

Pre-imaginal exposure to Oberon® disrupts fatty acid composition, cuticular hydrocarbon profile and sexual behavior in Drosophila melanogaster adults

2021

International audience; Oberon® is a commercial formulation of spiromesifen, a pesticide inhibitor of lipid biosynthesis via acetyl CoA carboxylase, widely used in agricultural crop protection. However, its mode of action requires further analysis. We currently examined the effect of this product on Drosophila melanogaster as a non-target and model organism. Different concentrations of spiromesifen were administered by ingestion (and contact) during pre-imaginal development, and we evaluated its delayed action on adults. Our results suggest that spiromesifen induced insecticidal activity on D. melanogaster. Moreover, spiromesifen treatment significantly increased the duration of larval and …

Male0106 biological sciencesInsecticidesmedicine.medical_specialtyPhysiologyHealth Toxicology and MutagenesisAnimal ScalesBiologyToxicology01 natural sciencesBiochemistrySexual Behavior Animal03 medical and health sciencessexual behaviorInternal medicineLipid biosynthesisMelanogastermedicineAnimalsSpiro CompoundsMode of action030304 developmental biology0303 health sciencesLarvacuticular hydrocarbonsFatty AcidsfungiAcetyl-CoA carboxylasetoxicityLipid metabolismCell BiologyGeneral Medicinebiology.organism_classificationspiromesifenHydrocarbons[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology010602 entomologyDrosophila melanogasterEndocrinologyToxicityFemaleDrosophila melanogasterComparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
researchProduct

Sexual and postmating reproductive isolation between allopatric Drosophila montana populations suggest speciation potential

2011

This work was funded by a European Commission Research Training Grant RTN2-2001-00049, the Centre of Excellence for Evolutionary Research at the University of Jyväskylä and a Marie Curie Initial Training Network, ‘Understanding the evolutionary origin of biological diversity’ (ITN-2008-213780 SPECIATION) Background: Widely distributed species with populations adapted to different environmental conditions can provide valuable opportunities for tracing the onset of reproductive incompatibilities and their role in the speciation process. Drosophila montana, a D. virilis group species found in high latitude boreal forests in Nearctic and Palearctic regions around the globe, could be an excellen…

Male0106 biological sciencesSympatryCanadaGenetic SpeciationEvolutionQH301 BiologyAllopatric speciationBiologyPremating isolationCourtship song010603 evolutionary biology01 natural sciencesEcological speciationDivergence03 medical and health sciencesQH301Hybrid zoneMelanogasterGenetic algorithmQH359-425AnimalsPatternsSelectionFinlandEcology Evolution Behavior and Systematics030304 developmental biologyIncipient speciation0303 health sciencesEcologyReproductionReproductive isolationMating Preference AnimalIncipient speciationReinforcementFertilityGenetics PopulationPhenotypeGenetic SpeciationEvolutionary biologyPerspectiveDrosophilaFemaleSexual Selection; Reproductive Barrier; Sexual Conflict; Cross Type; Copulation DurationResearch ArticleBMC Evolutionary Biology
researchProduct

Intraspecific competition affects population size and resource allocation in an ant dispersing by colony fission

2010

Intraspecific competition is a pervasive phenomenon with important ecological and evolutionary consequences, yet its effect in natural populations remains controversial. Although numerous studies suggest that in many cases populations across all organisms are limited by density-dependent processes, this conclusion often relies on correlative data. Here, using an experimental approach, we examined the effect of intraspecific competition on population regulation of the ant Aphaenogaster senilis. In this species females are philopatric while males disperse by flying over relatively long distances. All colonies were removed from 15 experimental plots, except for one focal colony in each plot, w…

Male0106 biological sciencesTime FactorsPopulationForagingresource allocationantsBiology010603 evolutionary biology01 natural sciencesPopulation densityIntraspecific competitionNestAnimalsSocial BehavioreducationresilienceEcology Evolution Behavior and SystematicsDemographydensityeducation.field_of_studyEcologyAnts010604 marine biology & hydrobiologycolony fissionAphaenogaster senilisBrood[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate ZoologyDensity dependencedensity dependencepopulation growthFemalePhilopatryColoby Fission
researchProduct

Relationship between inflammatory biomarkers and testosterone levels in male master athletes and non-athletes.

2021

Background Aging is often associated with low-grade systemic inflammation and reduced anabolic hormone levels. To investigate whether lifelong exercise training can decrease the age-related low-grade inflammation and anabolic hormone levels, we examined hormonal and inflammatory parameters among highly-trained male masters athletes and age-matched non-athletes. Methods From 70 elite power and endurance master athletes – EMA (51.3 ± 8.0 yr), 32 young controls - YC (23.7 ± 3.9 yr) and 24 untrained age-matched controls - MAC (47.2 ± 8.0 yr) venous blood was drawn to measure inflammatory parameters (interleukin-6 [IL-6], tumor necrosis factor-α [TNF-α] and interleukin-10 [IL-10]) and circulatin…

Male0301 basic medicineAgingAnabolismbiomarkkeritSystemic inflammationBiochemistryhypogonadismi0302 clinical medicineEndocrinologySex hormone-binding globulinSex Hormone-Binding GlobulinMedicineTestosteronehormonaaliset vaikutuksetTestosteronetulehdusbiologyMiddle Agedkeski-ikäisetmiehetmedicine.symptomLuteinizing hormoneAdultmedicine.medical_specialtyolder athletes03 medical and health sciencesmaster athletesInternal medicineGeneticsHumanshypogonadismExerciseMolecular Biologysukupuolihormonitbusiness.industryFree androgen indexAthleteshormonal profileCell Biologybiology.organism_classificationikääntyminen030104 developmental biologyEndocrinologyAthletesinflammationbiology.proteintestosteronibusinessBiomarkers030217 neurology & neurosurgeryurheilijatHormone
researchProduct

Drosophila Acquires a Long-Lasting Body-Size Memory from Visual Feedback

2019

Summary Grasping an object or crossing a trench requires the integration of information on the operating distance of our limbs with precise distance estimation. The reach of our hands and step size of our legs are learned by the visual feedback we get during our actions. This implicit knowledge of our peripersonal space is first acquired during infancy but will be continuously updated throughout our whole life [ 1 ]. In contrast, body size of holometabolous insects does not change after metamorphosis; nevertheless, they do have to learn their body reaches at least once. The body size of Drosophila imagines can vary by about 15% depending on environmental factors like food quality and temper…

Male0301 basic medicineMemory Long-Termmedia_common.quotation_subjectBiologyGeneral Biochemistry Genetics and Molecular BiologyMemorizationMotion (physics)03 medical and health sciences0302 clinical medicineFeedback SensoryAnimalsBody SizeContrast (vision)Computer visionSet (psychology)media_commonLong-term memorybusiness.industryDrosophila melanogaster030104 developmental biologyClimbingVisual PerceptionMemory consolidationArtificial intelligenceGeneral Agricultural and Biological SciencesbusinessParallaxPhotic Stimulation030217 neurology & neurosurgeryCurrent Biology
researchProduct

Fruit and vegetable consumption in Europe according to gender, educational attainment and regional affiliation—A cross-sectional study in 21 European…

2020

Objective The purpose of the present study was to examine fruit and vegetable consumption according to gender, educational attainment and regional affiliation in Europe. Design Cross-sectional study. Setting 21 European countries. Participants 37 672 adults participating in the 7th round of the European Social Survey. Main outcome measures Fruit and vegetable consumption was measured using two single frequency questions. Responses were dichotomized into low (<once a day) and high (≥once a day) consumption. The association between consumption of fruit and vegetables and gender, educational level, regional affiliation was examined using logistic regression analyses. Results Overall, females s…

Male0301 basic medicinePhysiologyCross-sectional studySocial SciencesLogistic regressionGeographical LocationsMathematical and Statistical TechniquesEndocrinology0302 clinical medicineSociologyVegetablesMedicine and Health SciencesEurope Eastern030212 general & internal medicineHealth Systems StrengtheningMultidisciplinaryStatisticsQREukaryotaRegression analysisPlantsResearch AssessmentMiddle AgedType 2 DiabetesEuropean Social SurveyPeer reviewEuropeGeographyPhysical SciencesRegression AnalysisEducational StatusMedicineFemaleResearch ArticleSystematic ReviewsEndocrine DisordersScienceResearch and Analysis MethodsDiet SurveysEducationFruitsOddsVDP::Medisinske Fag: 700::Helsefag: 800::Ernæring: 81103 medical and health sciencesSex FactorsDiabetes MellitusHumansStatistical MethodsEducational AttainmentConsumption (economics)Health Care Policy030109 nutrition & dieteticsOrganismsFood ConsumptionBiology and Life SciencesEducational attainmentDietHealth CareCross-Sectional StudiesDiet and Type 2 DiabetesMetabolic DisordersFruitPeople and PlacesPhysiological ProcessesMathematicsDemographyPLOS ONE
researchProduct