Search results for "Activity"
showing 10 items of 7178 documents
Extracellular vesicles and high‐density lipoproteins: Exercise and oestrogen‐responsive small RNA carriers
2023
Decreased systemic oestrogen levels (i.e., menopause) affect metabolic health. However, the detailed mechanisms underlying this process remain unclear. Both oestrogens and exercise have been shown to improve metabolic health, which may be partly mediated by circulating microRNA (c-miR) signalling. In recent years, extracellular vesicles (EV) have increased interest in the field of tissue crosstalk. However, in many studies on EV-carried miRs, the co-isolation of high-density lipoprotein (HDL) particles with EVs has not been considered, potentially affecting the results. Here, we demonstrate that EV and HDL particles have distinct small RNA (sRNA) content, including both host and nonhost sRN…
Hairy Garlic (Allium subhirsutum) from Sicily (Italy): LC-DAD-MSn Analysis of Secondary Metabolites and In Vitro Biological Properties
2020
Allium subhirsutum, known as hairy garlic, is a bulbous plant widespread in the Mediterranean area and locally used as a food and spice. In the present study, the chemical profile of the ethanolic extracts from bulbs (BE) and aerial parts (APE) were analyzed by HPLC-ESI-MSn, and antioxidant properties were evaluated by DPPH, ABTS and TEAC assays. The traditional use in the diet, and the well documented biological activity of Allium species suggest a potential as a new nutraceutical. For this reason, the potential usefulness of this food can be considered in the treatment and prevention of degenerative Alzheimer disease. For this reason, acetylcholinesterase inhibitory property was investiga…
Johtamisen eettiset konfliktit vahingoittavat työhyvinvointia suomalaisissa kasvuyrityksissä
2019
Kiinnostus eettistä johtamista eli johdon ja organisaation hyviä ja oikeudenmukaisia käytänteitä ja niiden vaikutuksia kohtaan on lisääntynyt. Eettinen johtaminen välittyy sekä työntekijöiden että asiakkaiden hyvinvointiin, ja se selittää jopa kolmanneksen organisaation innovaatiokyvystä. Epäeettinen toiminta ja sen tuottamat konfliktit taas aiheuttavat monia yksilöille, ryhmille ja organisaatioille epäedullisia seurauksia. nonPeerReviewed
Ethnographic Interventions: A Strategy and Experiments in Mapping Sociospatial Practices
2007
A growing awareness exists of the possibilities of architectural research adopting working methods used by artists. Many artists have adapted ethnographic methodologies to map site specificity and issues related to community and sociospatial practices. This paper draws on related examples of art practice to formulate a specific research strategy: ethnographic intervention. Ethnographic intervention has three characteristics: (a) ethnographic mapping of spatial practices on site, (b) the possibility of a horizontal replication of the study, and (c) an intervention protocol. We define ethnographic mapping as a critical process directed towards a specific cultural, social, or architectural sit…
Evaluación y clasificación de las revistas científicotécnicas españolas de Ciencias de la Actividad Física y el Deporte
2008
En este artículo se evalúan y clasifican las revistas españolas de Ciencias de la Actividad Física y el Deporte (CCAFD), atendiendo a su calidad global. Para ello se aplica un modelo de evaluación, validado con anterioridad, que combina 23 indicadores relativos a diferentes características de las revistas (formales, de contenido científico y difusión). De esta manera pueden clasificarse las publicaciones periódicas en cuatro categorías de calidad: ‘muy alta’, ‘alta’, ‘media’ y ‘baja’. Los resultados indican que ninguna de las 28 publicaciones existentes alcanza la categoría superior, el 25% obtiene una calidad ‘alta’, el 50% una calidad ‘media’ y otro 25% una calidad ‘baja’. Aunque se obser…
Assessment and classification of Spanish scientific-technical journals of Physical Activity and Sport Sciences
2008
This paper evaluates and classifies Spanish Physical Activity and Sports Science journals according to their overall quality. A previously validated assessment model combining 23 indicators of style, scientific content and diffusion characteristics was used for this purpose. This model classifies journals into four quality categories: ‘very high’, ‘high’, ‘medium’ and ‘low’. None of the 28 journals studied fell into the top category, 25% fell into the ‘high’ category, 50% into the ‘medium’ category, and the remaining 25% into the ‘low’ category. A general improvement was observed compared to previous assessments of these journals, although deficient standardization and a non frequent use of…
Synthesis and Antiproliferative Activity of 2,5-bis(3′-Indolyl)pyrroles, Analogues of the Marine Alkaloid Nortopsentin
2013
2,5-bis(3′-Indolyl)pyrroles, analogues of the marine alkaloid nortopsentin, were conveniently prepared through a three step procedure in good overall yields. Derivatives 1a and 1b exhibited concentration-dependent antitumor activity towards a panel of 42 human tumor cell lines with mean IC50 values of 1.54 μM and 0.67 μM, respectively. Investigating human tumor xenografts in an ex-vivo clonogenic assay revealed selective antitumor activity, whereas sensitive tumor models were scattered among various tumor histotypes.
Lipas data 04/2023
2023
This data includes all sport facilities in Lipas database on 23.4.2023 and basic attribute information about the places. The data is classified and each sport facility has its own Lipas ID. The data is provided as Esri Shapefiles (points, routes and areas). Tämä aineisto sisältää kaikki Lipas-tietokannan liikuntapaikat ja aineistotiedot 23.4.2023. Data on luokiteltu, ja jokaiselle liikuntapaikalle on oma Lipas-ID. Data on tarjolla Esri Shapefile -muodossa (pisteet, reitit ja alueet).
Lipas-data 04/2022
2022
Tämä aineisto sisältää kaikki Lipas-tietokannan liikuntapaikat ja aineistotiedot 29.4.2022. Data on luokiteltu, ja jokaiselle liikuntapaikalle on oma Lipas-ID. Data on tarjolla Esri Shapefile -muodossa (pisteet, reitit ja alueet). This data includes all sport facilities in Lipas database on 29.4.2022 and basic attribute information about the places. The data is classified and each sport facility has its own Lipas ID. The data is provided as Esri Shapefiles (points, routes and areas) in Finnish, Swedish and English.
Lipas-data 10/2022
2022
Tämä aineisto sisältää kaikki Lipas-tietokannan liikuntapaikat ja aineistotiedot 20.10.2022. Data on luokiteltu, ja jokaiselle liikuntapaikalle on oma Lipas-ID. Data on tarjolla Esri Shapefile -muodossa (pisteet, reitit ja alueet). This data includes all sport facilities in Lipas database on 20.10.2022 and basic attribute information about the places. The data is classified and each sport facility has its own Lipas ID. The data is provided as Esri Shapefiles (points, routes and areas) in Finnish, Swedish and English.