Search results for "Agaric"

showing 10 items of 41 documents

Biogeneration of 1-octen-3-ol by lipoxygenase and hydroperoxide lyase activities of Agaricus bisporus

2001

Abstract The biogeneration of 1-octen-3-ol by lipoxygenase and associated hydroperoxide lyase activities of a homogenate of the cultivated mushroom Agaricus bisporus was investigated using linoleic acid as a substrate. The optimal substrate and protein concentrations were 1.5 mM and 1.5 mg ml −1 , respectively. The V max value for the enzymic coupled reaction lipoxygenase–hydroperoxide lyase was 6 μg of 1-octen-3-ol ml −1 min −1 , with a K m value of 0.3×10 −3 M. The highest enzymic activity was observed in the presence of pure oxygen (22.9 μg of 1-octen-3-ol ml −1 ), with a bioconversion yield of 36%. The production of 380 μg 1-octen-3-ol per g of mushroom homogenate was demonstrated using…

MushroomChromatographybiologyBioconversionLinoleic acidSubstrate (chemistry)BioengineeringLyaseApplied Microbiology and BiotechnologyBiochemistrychemistry.chemical_compoundLipoxygenasechemistry1-Octen-3-olbiology.proteinOrganic chemistryAgaricus bisporusProcess Biochemistry
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Simultaneous Determination of Thiamin and Riboflavin in Mushrooms by Liquid Chromatography

2001

A simple, fast, inexpensive, and reliable method useful for the simultaneous, routine determination of thiamin and riboflavin in mushrooms is examined. It uses the extraction procedure, with slight modifications, proposed by the AOAC for the extraction of thiamin and riboflavin, followed by a liquid chromatographic separation on a reversed-phase Spherisorb ODS column with methanol/water as mobile phase gradient. Fluorometric detection is used at the following excitation and emission wavelengths, respectively, 360 and 425 nm in the case of thiamin and 422 and 515 nm for riboflavin. The analytical parameters of linearity, the precision of the method (RSD = 2.45 and 2.51% for thiamin and ribof…

MushroomMeasurement methodChromatographyChemistryRiboflavinExtraction (chemistry)RiboflavinGeneral ChemistryChromatographic separationchemistry.chemical_compoundSpectrometry FluorescenceSpherisorb ODSPhase gradientMethanolAgaricalesGeneral Agricultural and Biological SciencesChromatography LiquidJournal of Agricultural and Food Chemistry
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The Role of Medicinal Mushrooms in Brain Cancer Therapies: Review.

2021

Medicinal mushrooms are considered an unlimited source of polysaccharides (mainly β-glucans) and polysaccharide-protein complexes and possess various immunological and anticancer properties. In addition, their use in integrative medicine leads to a clear reduction of side effects in patients undergoing chemotherapy or radiotherapy. The literature reports a number of beneficial effects of using mushrooms as health supplements in patients affected by high-grade glioma. The effects of medicinal mushrooms on side effects in patients with brain cancer and a case study report are also described in this review.

Oncologymedicine.medical_specialtymedicine.medical_treatmentMEDLINEApplied Microbiology and BiotechnologyBrain cancerStudy reportPolysaccharidesInternal medicineGliomaDrug DiscoverymedicineHumansIn patientintegrative therapies brain cancer glioblastoma medicinal mushrooms mycotherapeutic supportPharmacologyChemotherapybusiness.industryBrain Neoplasmsmedicine.diseaseRadiation therapySettore BIO/03 - Botanica Ambientale E ApplicataDietary SupplementsIntegrative medicinebusinessAgaricalesInternational journal of medicinal mushrooms
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Evaluation of pulsed electric field-assisted extraction on the microstructure and recovery of nutrients and bioactive compounds from mushroom (Agaric…

2022

Pulsed electric field (PEF) is a sustainable innovative technology that allows for the recovery of nutrients and bioactive compounds from vegetable matrices. A. bisporus was chosen for its nutritional value and the effect of PEF pretreatment was evaluated using different conditions of electric field (2–3 kV/cm), specific energy (50–200 kJ/kg) and extraction time (0–6 h) to obtain the best conditions for nutrient and bioactive compound extraction. Spectrophotometric methods were used to evaluate the different compounds, along with an analysis of mineral content by inductively coupled plasma mass spectrometry (ICP-MS) and the surface was evaluated using scanning electron microscopy (SEM). In …

OptimizationMushroomsFiltration and SeparationTecnologia dels alimentsAgaricus bisporusBoletsAliments enriquitspulsed electric field; bioactive compounds; optimization; mushrooms; <i>Agaricus bisporus</i>Pulsed electric fieldBioactive compoundsAnalytical Chemistry
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Antibacterial activity of Mediterranean Oyster mushrooms, species of genus Pleurotus (higher Basidiomycetes).

2013

Extracts of the Mediterranean culinary-medicinal Oyster mushrooms Pleurotus eryngii var. eryngii, P. eryngii var. ferulae, P. eryngii var. elaeoselini, and P. nebrodensis were tested for their in vitro growth inhibitory activity against a group of bacterial reference strains of medical relevance: Staphylococcus aureus ATCC 25923, S. epidermidis RP62A, Pseudomonas aeruginosa ATCC 15442, and Escherichia coli ATCC10536. All of the Pleurotus species analyzed inhibited the tested microorganisms in varying degrees. The data included in this paper for P. nebrodensis and P. eryngii var. elaeoselinii are new reports.

OysterMicroorganismStaphylococcusHuman pathogenmedicine.disease_causePleurotusApplied Microbiology and BiotechnologySpecies Specificitybiology.animalDrug DiscoveryBotanymedicineEscherichia coliPleurotus eryngiiFood scienceEscherichia coliPharmacologyPleurotusBiological Productsbiologybiology.organism_classificationAnti-Bacterial AgentsStaphylococcus aureusSettore BIO/03 - Botanica Ambientale E ApplicataPseudomonas aeruginosamedicinal mushrooms antibacterial activity Pleurotus human pathogensAntibacterial activityAgaricalesInternational journal of medicinal mushrooms
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Notes on a New Productive Strain of King Oyster Mushroom, Pleurotus eryngii (Higher Basidiomycetes), a Prized Italian Culinary-Medicinal Mushroom

2015

In this paper, the authors provide data on a culinary-medicinal, host-specific variety of P. eryngii species-complex that is known in Italy as "cardoncello". A species description, the techniques of isolation of a new strain (C-142-c), and the preparation of the substratum are illustrated. Data on the productivity of substratum inoculated with C-142-c strain and the nutritional value of cultivated "cardoncello" mushrooms are also provided.

Oysteranimal structuresPleurotusApplied Microbiology and BiotechnologySpecies descriptionMedicinal mushroomSpecies Specificitybiology.animalDrug DiscoveryBotanyHumansAgaricalesPleurotus eryngiiPharmacologyMushroomPleurotusbiologyStrain (biology)culinary-medicinal mushrooms Pleurotus eryngii mushroom strains cultivation cultural-morphological studies nutritional composition Italybiology.organism_classificationDietItalySettore BIO/03 - Botanica Ambientale E ApplicataAgaricalesNutritive ValuePhytotherapy
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Deciphering the Potential of Pre and Pro-Vitamin D of Mushrooms against Mpro and PLpro Proteases of COVID-19: An In Silico Approach

2022

Vitamin D&rsquo;s role in combating the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), the virus causing COVID-19, has been established in unveiling viable inhibitors of COVID-19. The current study investigated the role of pre and pro-vitamin D bioactives from edible mushrooms against Mpro and PLpro proteases of SARS-CoV-2 by computational experiments. The bioactives of mushrooms, specifically ergosterol (provitamin D2), 7-dehydrocholesterol (provitamin-D3), 22,23-dihydroergocalciferol (provitamin-D4), cholecalciferol (vitamin-D3), and ergocalciferol (vitamin D2) were screened against Mpro and PLpro. Molecular docking analyses of the generated bioactive protease complexes unr…

Pharmaceutical Scienceedible mushroomsMolecular Dynamics SimulationViral Nonstructural ProteinsAnalytical Chemistrypro-vitamin-DErgosterolDrug DiscoveryEndopeptidasespre-vitamin-DHumansProtease InhibitorsPhysical and Theoretical ChemistryVitamin DSARS-CoV-2Organic ChemistryProvitaminsin-silico studiesSettore CHIM/08 - Chimica FarmaceuticaCOVID-19 Drug TreatmentMolecular Docking SimulationChemistry (miscellaneous)Molecular MedicineAgaricalesedible mushrooms; SARS-CoV-2; pre-vitamin-D; pro-vitamin-D; in-silico studiesPeptide HydrolasesMolecules; Volume 27; Issue 17; Pages: 5620
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Do differences in chemical composition of stem and cap of Amanita muscaria fruiting bodies correlate with topsoil type?

2014

Fly agaric (Amanita muscaria) was investigated using a 1H NMR-based metabolomics approach. The caps and stems were studied separately, revealing different metabolic compositions. Additionally, multivariate data analyses of the fungal basidiomata and the type of soil were performed. Compared to the stems, A. muscaria caps exhibited higher concentrations of isoleucine, leucine, valine, alanine, aspartate, asparagine, threonine, lipids (mainly free fatty acids), choline, glycerophosphocholine (GPC), acetate, adenosine, uridine, 4-aminobutyrate, 6-hydroxynicotinate, quinolinate, UDP-carbohydrate and glycerol. Conversely, they exhibited lower concentrations of formate, fumarate, trehalose, α- an…

PhytochemistryAmanitaFungal Physiologylcsh:MedicineSoil SciencePhenylalanineMycologyPlant ScienceBiologyBiochemistryMicrobiologyAnalytical Chemistrychemistry.chemical_compoundSoilValineMicrobial PhysiologyMolecular Cell BiologyAsparagineFruiting Bodies Fungallcsh:ScienceEcosystemMicrobial MetabolismMultidisciplinaryAgaricSystems Biologylcsh:REcology and Environmental SciencesBiology and Life SciencesAgricultureCell BiologySoil Ecologybiology.organism_classificationQuinolinateTrehaloseChemistryBiochemistrychemistryPhysical Scienceslcsh:QIsoleucineAmanita muscariaResearch ArticlePloS one
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Review of current and “omics” methods for assessing the toxicity (genotoxicity, teratogenicity and nephrotoxicity) of herbal medicines and mushrooms

2012

Ethnopharmacological relevance: The increasing use of traditional herbal medicines around the world requires more scientific evidence for their putative harmlessness. To this end, a plethora of methods exist, more or less satisfying. In this post-genome era, recent reviews are however scarce, not only on the use of new "omics" methods (transcriptomics, proteomics, metabonomics) for genotoxicity, teratogenicity, and nephrotoxicity assessment, but also on conventional ones. Methods: The present work aims (i) to review conventional methods used to assess genotoxicity, teratogenicity and nephrotoxicity of medicinal plants and mushrooms; (ii) to report recent progress in the use of "omics" techn…

Proteomicsmedicine.medical_specialtyDrug-Related Side Effects and Adverse ReactionsHerbal MedicineOmicsBiologymedicine.disease_causeKidneyToxicologyNephrotoxicity03 medical and health sciences0302 clinical medicineTeratogenicityDrug DiscoverymedicineMethodsHumansTechnology PharmaceuticalIntensive care medicineEvaluationNephrotoxicity030304 developmental biologyPharmacology0303 health sciencesPlants Medicinalbusiness.industrySciences bio-médicales et agricolesOmics3. Good healthBiotechnologyTeratogens030220 oncology & carcinogenesisMedicine TraditionalGenotoxicitybusinessAgaricalesTranscriptomeGenotoxicityPredictive methodsMutagensPhytotherapyJournal of Ethnopharmacology
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Indirect oxidation of amino acid phenylhydrazides by mushroom tyrosinase.

2006

We have investigated oxidation of amino acid phenylhydrazides by mushroom tyrosinase in the presence of 4-tert-butylcatechol and N-acetyl-l-tyrosine. Spectrophotometric measurements showed gradual disappearance of 4-tert-butyl-o-benzoquinone, generated by oxidation of 4-tert-butylcatechol with sodium periodate, after addition of amino acid phenylhydrazides. However, the presence of the phenylhydrazides did not influence the concentration of 4-tert-butyl-o-benzoquinone formed during enzymatic oxidation. Oxygen consumption measurements demonstrated that in a mixture both compounds were oxidized but the reaction rate was proportional to the concentration of the catechol. In the oxidation of N-…

Reducing agentTyrosinaseBiophysicsagaritineHydrazideBiochemistrychemistry.chemical_compoundOrganic chemistryAmino AcidsMolecular Biologyhydrazidechemistry.chemical_classificationCatecholMolecular StructureSodium periodateMonophenol MonooxygenaseSpectrum AnalysishydrazineAmino acidPhenylhydrazinesOxygenAgaritineEnzymetyrosinaseo-quinonechemistryredox exchangeAgaricalesOxidation-ReductionBiochimica et biophysica acta
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