Search results for "BASAL"

Autofluorescence imaging of basal cell carcinoma by smartphone RGB camera

2015

The feasibility of smartphones for in vivo skin autofluorescence imaging has been investigated. Filtered autofluorescence images from the same tissue area were periodically captured by a smartphone RGB camera with subsequent detection of fluorescence intensity decreasing at each image pixel for further imaging the planar distribution of those values. The proposed methodology was tested clinically with 13 basal cell carcinoma and 1 atypical nevus. Several clinical cases and potential future applications of the smartphone-based technique are discussed.

Structural overprint of a late Paleozoic accretionary system in north-central Chile (34°-35°S) during post-accretional deformation

2009

En la Cordillera de la Costa de Chile, de 36° a 35°S, se encuentra expuesta la arquitectura coherentemente preservada de un prisma de acrecion del Paleozoico tardio, en cercana vecindad a un area entre los 34° y 35°S, donde el mismo esta fuertemente modificado por procesos postacrecionales. Estudiando las desviaciones de la arquitectura original, en esta region pueden ser perfectamente distinguidas estructuras sin- y post acrecionales. Al sur de los 35° se observa un contacto transicional entre dos unidades mayores, el cual refleja un cambio continuo en el modo de acrecion de la cuna acrecional antes de -305 Ma: las metagrauvacas estructuralmente suprayacentes de las series orientales muest…

Italian Euromelanoma Day Screening Campaign (2005-2007) and the planning of melanoma screening strategies.

2011

Although no study has definitively shown that unfocused screening of skin cancer is effective, many campaigns have been organized with the aim of increasing awareness on melanoma risk factors. The objective of this study was to analyse the results of the Skin Cancer Screening Day in Italy during the period 2005-2007, to determine the priorities for melanoma control plans in a Mediterranean country. A total of 5002 patients were screened by dermatologists in 31 cities. Individuals who considered themselves to have many naevi and those with a family history of melanoma showed a higher number of common and atypical naevi. Ten melanomas, 20 basal cell carcinomas and two squamous cell carcinomas…

Breast cancer cells exhibit selective modulation induced by different collagen substrates.

2008

During the invasive phase of malignant tumors, neoplastic cells break into the basal lamina and enter in contact with the underlying connective tissue, which concurrently undergoes extensive modifications. The aim of our present minireview is to focus the changes in the collagenous matrix occurring during breast cancer progression and to explore the possible effects of different collagen substrates on breast cancer cell behavior and proteomic modulation.

The era of reference genomes in conservation genomics

2022

Progress in genome sequencing now enables the large-scale generation of reference genomes. Various international initiatives aim to generate reference genomes representing global biodiversity. These genomes provide unique insights into genomic diversity and architecture, thereby enabling comprehensive analyses of population and functional genomics, and are expected to revolutionize conservation genomics.

TALPID3 controls centrosome and cell polarity and the human ortholog KIAA0586 is mutated in Joubert syndrome (JBTS23)

2015

Joubert syndrome (JBTS) is a severe recessive neurodevelopmental ciliopathy which can affect several organ systems. Mutations in known JBTS genes account for approximately half of the cases. By homozygosity mapping and whole-exome sequencing, we identified a novel locus, JBTS23, with a homozygous splice site mutation in KIAA0586 (alias TALPID3), a known lethal ciliopathy locus in model organisms. Truncating KIAA0586 mutations were identified in two additional patients with JBTS. One mutation, c.428delG (p.Arg143Lysfs*4), is unexpectedly common in the general population and may be a major contributor to JBTS. We demonstrate KIAA0586 protein localization at the basal body in human and mouse p…

La qualità tecnologica utile di prodotti edilizi innovativi

2014

Rapid shifting of a deep magmatic source at Fagradalsfjall volcano, Iceland

2022

AbstractRecent Icelandic rifting events have illuminated the roles of centralized crustal magma reservoirs and lateral magma transport1–4, important characteristics of mid-ocean ridge magmatism1,5. A consequence of such shallow crustal processing of magmas4,5 is the overprinting of signatures that trace the origin, evolution and transport of melts in the uppermost mantle and lowermost crust6,7. Here we present unique insights into processes occurring in this zone from integrated petrologic and geochemical studies of the 2021 Fagradalsfjall eruption on the Reykjanes Peninsula in Iceland. Geochemical analyses of basalts erupted during the first 50 days of the eruption, combined with associate…

ANALYSIS OF THE SEXUAL VARIABILITY IN THE SHELL OF THE SPANISH UPPER CRETACEOUS TURTLE DORTOKA VASCONICA (PAN-PLEURODIRA, DORTOKIDAE)

2021

The present study characterizes the morphological variability related to the sexual dimorphism in the shells of the Spanish Upper Cretaceous turtle  Dortoka vasconica . This study is based on the material from its type locality: Lano, Burgos. Two morphotypes were identified there based on the posterior plastral area as well as two for the anterior plastral lobe. However, a correlation with the previously indicated morphotypes could not be established due to the disarticulation of the specimens and the limited information available on the sexual dimorphism of Pleurodira. The morphological variability previously identified for  Dortoka vasconica  is analysed here through a quantitative approa…

Origin of Blue Sapphire in Newly Discovered Spinel–Chlorite–Muscovite Rocks within Meta-Ultramafites of Ilmen Mountains, South Urals of Russia: Evide…

2019

Blue sapphire of gem quality was recently discovered in spinel&ndash