Search results for "BM"
showing 10 items of 1459 documents
The role of osteoprotegerin in the crosstalk between vessels and bone: Its potential utility as a marker of cardiometabolic diseases
2018
International audience; Among the numerous molecules that are being studied for their potential utility as biomarkers of cardiovascular diseases, much interest has been shown in the superfamily of tumor necrosis factor (TNF) receptors. Members of this family include osteoprotegerin (OPG) and its ligands, which are receptor activators of nuclear factor κB ligand (RANKL) and TNF-related apoptosis-inducing ligand (TRAIL). These signals may be expressed and regulated, and their functions could be involved in several physiological and pathological processes. The relationship between bone regulatory proteins and vascular biology has attracted attention, and it has been suggested that OPG may medi…
Sense and Antisense DMPK RNA Foci Accumulate in DM1 Tissues during Development.
2015
International audience; Myotonic dystrophy type 1 (DM1) is caused by an unstable expanded CTG repeat located within the DMPK gene 3'UTR. The nature, severity and age at onset of DM1 symptoms are very variable in patients. Different forms of the disease are described, among which the congenital form (CDM) is the most severe. Molecular mechanisms of DM1 are well characterized for the adult form and involve accumulation of mutant DMPK RNA forming foci in the nucleus. These RNA foci sequester proteins from the MBNL family and deregulate CELF proteins. These proteins are involved in many cellular mechanisms such as alternative splicing, transcriptional, translational and post-translational regul…
Comptabilité à base d'activités (ABC) et activités informatiques : une contribution à l'amélioration des processus informatiques d'une banque
2010
The aim of the paper is to describe the Activity-based Costing and Management methods applied in France. For that purpose, we use a literature review and a case study. In a first time, we analyse the origins of the methods and their diffusion. Then we present the French situation. Finally, we propose a case study that takes place in a French bank. Our paper shows that the ABC and ABM methods are as developed in France as in the Anglo-Saxon countries and that the methods are strategically oriented.
The Added Value of Remote Technology in Cardiac Rehabilitation on Physical Function, Anthropometrics, and Quality of Life: Cluster Randomized Control…
2023
Background Cardiovascular diseases (CVDs) cause most deaths globally and can reduce quality of life (QoL) of rehabilitees with cardiac disease. The risk factors of CVDs are physical inactivity and increased BMI. With physical activity, it is possible to prevent CVDs, improve QoL, and help maintain a healthy body mass. Current literature shows the possibilities of digitalization and advanced technology in supporting independent self-rehabilitation. However, the interpretation of the results is complicated owing to the studies’ high heterogeneity. In addition, the added value of this technology has not been studied well, especially in cardiac rehabilitation. Objective We aimed to examine the…
COVID Obesity: A One-Year Narrative Review
2021
On 11 March 2020, coronavirus disease 2019 (COVID-19) was declared a pandemic by the World Health Organization (WHO). This study focuses on a narrative review about the illness during the first year of the pandemic in relation to obesity. Databases were used to search studies published up to 8 December 2020. In total, 4430 articles and other scientific literature were found, and 24 articles were included in this one-year narrative review. The mean BMI value of severe COVID-19 patients ranged from 24.5 to 33.4 kg/m2, versus 2 for non-severe patients. Articles using the terms obesity or overweight without indicating the BMI value in these patients were common, but this is not useful, as the a…
Depletion of
2020
Child obesity constitutes a risk factor for developing insulin resistance which, if sustained, could lead to more severe conditions like type 2 diabetes (T2D) in adulthood. Our study identified previously unknown species whose depletion (Blautia luti and Blautia wexlerae) is associated with insulin resistance in obese individuals. Our results also indicate that these bacterial species might help to reduce inflammation causally linked to obesity-related complications. Childhood is considered a window of opportunity to tackle obesity. These new findings provide, therefore, valuable information for the future design of microbiota-based strategies for the early prevention of obesity-related com…
Obmowa, osądzanie, narzekanie czy milczenie? Rozważania Ojców Pustyni
2021
Pod koniec III wieku rozpoczyna się ruch monastyczny zainicjowany przez św. Antoniego. Powstała w ten sposób nowa forma ascezy charakteryzująca się zerwaniem ze światem, społeczeństwem (anachoreza, czyli pustelnictwo). Odtąd życie pustelników ma być pełne wyrzeczeń, na które składają się post, wstrzemięźliwość seksualna, modlitwa i praca, ale też milczenie. Wierzono bowiem, że tylko w ciszy brat otrzyma szansę spotkania z Bogiem, że usłyszy Jego Słowa i tym samym wkroczy w Jego tajemnicę, a potem będzie mógł innych do tej tajemnicy doprowadzić dzięki potędze miłości i pokory. Milczenie, zachowanie ciszy, powstrzymywanie się przed uwolnieniem słów były niezwykle ważnymi i częstymi tematami p…
Development of innovative blends of sweeteners and sweetness enhancers (S&SE) using sweet taste receptor studies
2023
The NAOMI (Nasal Odorant Metabolites) consortium: an international, multidisciplinary consortium investigating how metabolites resulting from nasal e…
2021
International audience; A functional sense of smell is essential for evaluating and enjoying food, receiving information about conspecifics, and detecting threats via airborne chemical cues. Olfactory dysfunction has been associated with an impaired quality of life, reflected by a higher incidence of undesirable mental states such as depression and social insecurity. Addressing and overcoming related olfactory dysfunction issues require a detailed understanding of peripheral and central processes involved in olfaction. Consequently, there is a growing body of research unravelling molecular and cellular interactions that shape olfactory sensation. Recent studies have demonstrated that in the…
Yhdistetyn kestävyys- ja voimaharjoittelun vaikutus pH:hon, laktaattiin ja submaksimaaliseen kestävyyssuorituskykyyn kahdella erilaisella ruokavaliol…
2013
Johdanto. Elimistön emäksisyyttä lisäämällä on pystytty parantamaan sekä anaerobista että aerobista suorituskykyä. Tämän tutkimuksen tarkoituksena oli selvittää, miten emästä tuottava normaaliproteiininen ja runsaasti kasviksia ja hedelmiä sisältävä ruokavalio vaikuttaa elimistön happo-emästasapainoon, submaksimaaliseen kestävyyssuorituskykyyn, pH:hon ja laktaatin tuottoon verrattuna happamuutta tuottavaan ruokavalioon 12 viikon yhdistetyn kestävyys- ja voimaharjoittelun aikana. Menetelmät. Tutkimukseen osallistui yhteensä 49 kuntoliikuntaa harrastavaa naista ja miestä, jotka jaettiin kahteen ruokavalioryhmään (Emäs / Hapan). Emäsryhmän ruokavalio oli arvioitu PRAL (potential renal acid loa…