Search results for "Basal Cell"

showing 10 items of 129 documents

Predicting Death in Patients with Squamous Cell Carcinoma of the Tongue

2019

Tongue squamous cell carcinoma (TSCC) accounts for 40% of all squamous cell carcinoma involving the mucosal surface of the oral cavity. TSCC is highly invasive and aggressive and, nowadays, TNM staging system is considered the gold standard in predicting patients’ outcomes. [...]

Pathologymedicine.medical_specialtybusiness.industryTongue squamous cell carcinomaPredicting Death Squamous Cell Carcinoma TongueGold standard (test)TNM staging systemOral cavitystomatognathic diseasesmedicine.anatomical_structureTongueMedicineIn patientBasal cellbusinessThe XV National and III International Congress of the Italian Society of Oral Pathology and Medicine
researchProduct

Evaluation of p53, Caspase-3, Bcl-2, and Ki-67 markers in oral squamous cell carcinoma and premalignant epithelium in a sample from Alava Province (S…

2013

Objectives: The objective of this study was to determine whether alterations in the expression of p53, caspase-3 Bcl-2, and ki-67 appear early in premalignant oral epithelium and show clonal behavior. Study Design: Samples from 41 tumors with their adjacent non-tumor epithelia were immunohistochemically analyzed using monoclonal antibodies that recognize p53, caspase-3, Bcl-2, and Ki-67 Results: A statistically significant association was found between the expression in tumor and adjacent epithelium of p53, caspase-3, and Bcl-2 but not of k-67. A significant association was observed between the expression of ki-67 and p53 in both localizations. In non-tumor (premalignant) epithelium samples…

Pathologymedicine.medical_specialtymedicine.drug_classCellCaspase 3OdontologíaMonoclonal antibodyEpitheliummedicineBiomarkers TumorHumansBasal cellGeneral DentistryMouth neoplasmOral Medicine and PathologybiologyCaspase 3:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludEpitheliummedicine.anatomical_structureKi-67 AntigenOtorhinolaryngologyApoptosisSpainKi-67UNESCO::CIENCIAS MÉDICASbiology.proteinCancer researchCarcinoma Squamous CellSurgeryResearch-ArticleMouth NeoplasmsTumor Suppressor Protein p53Precancerous ConditionsMedicina Oral, Patología Oral y Cirugía Bucal
researchProduct

Das basaloide Plattenepithelkarzinom (BSC) der Mundschleimhaut

1997

The basaloid-squamous carcinoma (BSC) that was first described in 1986 by Wain et al. for the head and neck region is a rare distinct variant of squamous cell carcinoma (SCC). The cardinal histopathologic feature is a biphasic cellular pattern of basaloid and squamous components. BSC has been confused with solid adenoid cystic carcinoma (ACC). Although the number of reported cases is small, BSC appears biologically virulent, with a propensity to aggressive local behavior, early regional and distant metastasis, and subsequent poor survival. We report the clinicopathological characteristics of 4 new cases and compare their immunohistochemical features with those of solid ACC and conventional …

Pathologymedicine.medical_specialtyurogenital systemAdenoid cystic carcinomabusiness.industryvirusesEpithelial carcinomabiochemical phenomena metabolism and nutritionmedicine.diseaseGlandular Patternstomatognathic diseasesOtorhinolaryngologyCarcinomamedicineImmunohistochemistrySurgeryBasal cellOral SurgeryDifferential diagnosisMouth mucosabusinesspsychological phenomena and processesOral and Maxillofacial Surgery
researchProduct

The interval since first symptoms until diagnosis of squamous cell carcinoma in the head and neck region is still a problem in southern Brazil.

2020

Background The aim was to examine the interval since first symptoms until final diagnosis of squamous cell carcinoma (SCC) in the head and neck region in southern Brazil. Material and Methods The individuals were prospectively selected and underwent anamnesis, physical examination and interview in the first medical consultation at a Cancer Hospital from south of Brazil. Results From 488 patients who underwent clinical examination, 105 were included in the study with diagnosis of SCC. Patients average interval from first symptoms to final diagnosis was 152 days (median 86; max:1105; min: 1), the average professional interval was 108 days (median: 97; max:525; min: 1) , and the average total …

Pediatricsmedicine.medical_specialtymedicine.medical_treatmentPhysical examination03 medical and health sciences0302 clinical medicinemedicineHumansBasal cellHead and neckGeneral DentistrySecondary preventionAnamnesisOral Medicine and Pathologymedicine.diagnostic_testbusiness.industryResearchSmokingCancer030206 dentistrymedicine.disease:CIENCIAS MÉDICAS [UNESCO]OtorhinolaryngologyLate diagnosisHead and Neck NeoplasmsUNESCO::CIENCIAS MÉDICASCarcinoma Squamous CellSurgeryDenturesbusinessBrazilNeckMedicina oral, patologia oral y cirugia bucal
researchProduct

Autofluorescence imaging of basal cell carcinoma by smartphone RGB camera

2015

The feasibility of smartphones for in vivo skin autofluorescence imaging has been investigated. Filtered autofluorescence images from the same tissue area were periodically captured by a smartphone RGB camera with subsequent detection of fluorescence intensity decreasing at each image pixel for further imaging the planar distribution of those values. The proposed methodology was tested clinically with 13 basal cell carcinoma and 1 atypical nevus. Several clinical cases and potential future applications of the smartphone-based technique are discussed.

PorphyrinsSkin NeoplasmsLightComputer scienceBiomedical EngineeringDermoscopyImage processingFluorescenceBiomaterialsOpticsmedicineHumansBasal cell carcinomaNevusSkinPhotobleachingPixelbusiness.industrySkin autofluorescenceNADmedicine.diseaseAtypical nevusAtomic and Molecular Physics and OpticsElectronic Optical and Magnetic MaterialsAutofluorescenceFluorescence intensityMicroscopy FluorescenceCarcinoma Basal CellRGB color modelCollagenSmartphonebusinessBiomedical engineeringJournal of Biomedical Optics
researchProduct

Italian Euromelanoma Day Screening Campaign (2005-2007) and the planning of melanoma screening strategies.

2011

Although no study has definitively shown that unfocused screening of skin cancer is effective, many campaigns have been organized with the aim of increasing awareness on melanoma risk factors. The objective of this study was to analyse the results of the Skin Cancer Screening Day in Italy during the period 2005-2007, to determine the priorities for melanoma control plans in a Mediterranean country. A total of 5002 patients were screened by dermatologists in 31 cities. Individuals who considered themselves to have many naevi and those with a family history of melanoma showed a higher number of common and atypical naevi. Ten melanomas, 20 basal cell carcinomas and two squamous cell carcinomas…

Program evaluationMaleCancer ResearchSkin NeoplasmsTime FactorsEpidemiologyBasal CellpreventionRisk Factorsself-surveillance80 and overSettore MED/35 - Malattie Cutanee E VenereeMedicineMass Screeningmelanoma screening campaignMelanoma prevention strategy Melanoma risk factors Melanoma screening campaign Self-surveillance Skin cancerFamily historyYoung adultChildMelanomaAged 80 and overeducation.field_of_studyNevus Pigmentedskin cancerMelanomaMiddle AgedMALIGNANT MELANOMA; screeningPrognosisOncologyItalymelanoma; screening; risk factors; prevention; prognosisChild PreschoolCarcinoma Squamous CellFemaleAdultmedicine.medical_specialtyAdolescentPopulationmelanoma prevention strategy; melanoma risk factors; melanoma screening campaign; self-surveillance; skin cancermelanoma prevention strategyYoung AdultPigmentedHumansmelanoma prevention strategy; melanoma risk factors; melanoma screening campaign; skin cancer; self-surveillancePreschooleducationNevusSocioeconomic statusMass screeningAgedbusiness.industrymelanoma risk factorsscreeningCarcinomaPublic Health Environmental and Occupational Healthmelanoma risk factorInfantmedicine.diseaseDermatologyMALIGNANT MELANOMASquamous CellCarcinoma Basal CellSelf-ExaminationSkin cancerbusinessProgram Evaluation
researchProduct

P254 Survivin detection in saliva samples from patients with oral squamous cell carcinoma

2007

Salivabusiness.industrySurvivinCancer researchMedicineBasal cellbusinessOral Oncology Supplement
researchProduct

Potential Non-Invasive Biomarkers for Early Diagnosis of Oral Squamous Cell Carcinoma

2021

This study aimed to investigate the role of a panel of salivary cytokines as biomarkers for early detection oral squamous cell carcinoma (OSCC), comparing their levels among healthy individuals, patients with oral leukoplakia (OL), and malignant lesions. Cytokine profiling analysis performed in a minimally invasive sample was correlated with clinicopathological variables in our patient cohorts. Unstimulated saliva was obtained from subjects with OSCC at early (n = 33) and advanced (n = 33) disease, OL with homogeneous (n = 33) and proliferative verrucous (n = 33) clinical presentations, and healthy controls (n = 25). Salivary IL-1α, IL-6, IL-8, IP-10, MCP-1, TNF-α, HCC-1, and PF-4 levels we…

Salivamedicine.medical_specialtynon-invasive biomarkerslcsh:MedicineDiseaseGastroenterologyArticleoral leukoplakia03 medical and health sciences0302 clinical medicinesaliva testingSaliva testingInternal medicineMedicineBasal cellmedicine.diagnostic_testbusiness.industrylcsh:RNon invasive biomarkersArea under the curve030206 dentistryGeneral Medicineoral cancer3. Good healthOral leukoplakiastomatognathic diseasestranslational research030220 oncology & carcinogenesisImmunoassaybusinessJournal of Clinical Medicine
researchProduct

Differentiation of seborrheic keratosis from basal cell carcinoma, nevi and melanoma by RGB autofluorescence imaging

2018

A clinical trial on the autofluorescence imaging of skin lesions comprising 16 dermatologically confirmed pigmented nevi, 15 seborrheic keratosis, 2 dysplastic nevi, histologically confirmed 17 basal cell carcinomas and 1 melanoma was performed. The autofluorescence spatial properties of the skin lesions were acquired by smartphone RGB camera under 405 nm LED excitation. The diagnostic criterion is based on the calculation of the mean autofluorescence intensity of the examined lesion in the spectral range of 515 nm–700 nm. The proposed methodology is able to differentiate seborrheic keratosis from basal cell carcinoma, pigmented nevi and melanoma. The sensitivity and specificity of the prop…

Seborrheic keratosisPathologymedicine.medical_specialty01 natural sciencesArticle010309 opticsLesion030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicine0103 physical sciencesmedicinePigmented NevusBasal cellBasal cell carcinomaneoplasmsintegumentary systembusiness.industryMelanomamedicine.diseaseAtomic and Molecular Physics and OpticsAutofluorescencemedicine.symptomSkin lesionbusinessBiotechnology
researchProduct

A method for skin malformation classification by combining multispectral and skin autofluorescence imaging

2018

As the incidence of skin cancer is still increasing worldwide, there is a high demand for early, non-invasive and inexpensive skin lesion diagnostics. In this article we describe and combine two skin imaging methods: skin autofluorescence (AF) and multispectral criterion p’. To develop this method, we used custom made prototype with 405 nm, 526 nm, 663 nm and 964 nm LED illuminations, perpendicular positioned linear polarizers, 515 nm filter and IDS camera. Our aim is to develop a skin lesion diagnostic device for primary care physicians who do not have experience in dermatology or skin oncology. In this study we included such common benign lesion groups as seborrheic keratosis, hyperkerato…

Seborrheic keratosismedicine.medical_specialtyintegumentary systembusiness.industryMelanomaHyperkeratosisPrimary careBenign lesionSkin autofluorescencemedicine.diseaseDermatologymedicineBasal cell carcinomaSkin cancerbusinessBiophotonics: Photonic Solutions for Better Health Care VI
researchProduct