Search results for "Biomedical engineering"
showing 10 items of 2020 documents
Hyperspectral imaging in perfusion and wound diagnostics – methods and algorithms for the determination of tissue parameters
2018
Abstract Blood perfusion is the supply of tissue with blood, and oxygen is a key factor in the field of minor and major wound healing. Reduced perfusion of a wound bed or transplant often causes various complications. Reliable methods for an objective evaluation of perfusion status are still lacking, and insufficient perfusion may remain undiscovered, resulting in chronic processes and failing transplants. Hyperspectral imaging (HSI) represents a novel method with increasing importance for clinical practice. Therefore, methods, software and algorithms for a new HSI system are presented which can be used to observe tissue oxygenation and other parameters that are of importance in supervising…
Water capillary absorption in porous media in different wettability conditions studied by Quantitative MRI and X-ray CT
2007
X-ray computed tomography (CT) and magnetic resonance imaging (MRI) have been successfully applied to study both the capillary properties of several samples of Lecce stone and the performances of treatments used for protection and conservation of historical stone artifacts. The presence of water inside the sample may be visualized by both MRI and X-ray CT. For the treated samples, the different dynamics of water absorption gives indirectly the efficacy of the polymer in the rock.
Thermodynamic and Kinetic Modeling of Co-utilization of Glucose and Xylose for 2,3-BDO Production by Zymomonas mobilis
2021
Prior engineering of the ethanologen Zymomonas mobilis has enabled it to metabolize xylose and to produce 2,3-butanediol (2,3-BDO) as a dominant fermentation product. When co-fermenting with xylose, glucose is preferentially utilized, even though xylose metabolism generates ATP more efficiently during 2,3-BDO production on a BDO-mol basis. To gain a deeper understanding of Z. mobilis metabolism, we first estimated the kinetic parameters of the glucose facilitator protein of Z. mobilis by fitting a kinetic uptake model, which shows that the maximum transport capacity of glucose is seven times higher than that of xylose, and glucose is six times more affinitive to the transporter than xylose.…
Amine functionalized ZrO2 nanoparticles as biocompatible and luminescent probes for ligand specific cellular imaging
2015
Surface functionalized ZrO2 nanoparticles show strong photoluminescence and are a versatile tool for cellular targeting due to their chemical functionality. They are highly photostable, biocompatible and amenable to coupling with bioligands (e.g. secondary goat anti-rabbit antibody (GAR) and tri-phenyl phosphine (TPP)) via carbodiimide chemistry. Antibody (GAR) functionalized ZrO2 nanoparticles were used to image the nuclear protein Sirt6, whereas triphenyl phosphonium ion (TPP) functionalized ZrO2 nanoparticles specifically targeted the mitochondria. The versatility and easiness of the ZrO2 surface modification opens up new possibilities for designing non-toxic water dispersible and photos…
Model Free Control for muscular force by Functional Electrical Stimulation using pulse width modulation
2016
International audience; Functional Electrical Stimulation (FES) is a useful technique for restoring functions for patients with neurological disorders. Muscle activities can be artificially driven through delivery of electrical pulses to skeletal muscles. Typically, muscles are activated by using constant stimulation train with a fixed parameters (amplitude, frequency and pulse width). In addition, the FES systems do not adapt the parameters stimulation to obtain a desired force response during the rehabilitation session. The purpose of this study is to investigate a real-time FES system for adapting automatically the stimulation parameters (stimulation pulse width) to track a desired force…
Remote Photoplethysmography Based on Implicit Living Skin Tissue Segmentation
2016
International audience; Region of interest selection is an essential part for remote photoplethysmography (rPPG) algorithms. Most of the time, face detection provided by a supervised learning of physical appearance features coupled with skin detection is used for region of interest selection. However, both methods have several limitations and we propose to implicitly select living skin tissue via their particular pulsatility feature. The input video stream is decomposed into several temporal superpixels from which pulse signals are extracted. Pulsatility measure for each temporal superpixel is then used to merge pulse traces and estimate the photoplethysmogram signal. This allows to select …
Parameter-free adaptive step-size multiobjective optimization applied to remote photoplethysmography
2018
International audience; In this work, we propose to reformulate the objective function of Independent Component Analysis (ICA) to make it a better posed problem in the context of Remote photoplethysmography (rPPG). In recent previous works, linear combination coefficients of RGB channels are estimated maximizing the non-Gaussianity of ICA output components. However, in the context of rPPG a priori knowledge of the pulse signal can be incorporated into the component extraction algorithm. To this end, the contrast function of regular ICA is extended with a measure of periodicity formulated using autocorrelation. This novel semi-blind source extraction method for measuring rPPG has the interes…
Automatic detection of P, QRS and T patterns in 12 leads ECG signal based on CWT
2016
International audience; In this paper, a new method based on the continuous wavelet transform is described in order to detect the QRS, P and T waves. QRS, P and T waves may be distinguished from noise, baseline drift or irregular heartbeats. The algorithm, described in this paper, has been evaluated using the Computers in Cardiology (CinC) Challenge 2011 database and also applied on the MIT-BIH Arrhythmia database (MITDB). The data from the CinC Challenge 2011 are standard 12 ECG leads recordings with full diagnostic bandwidth compared to the MITDB which only includes two leads for each ECG signal. Firstly, our algorithm is validated using fifty 12 leads ECG samples from the CinC collection…
Toward the development of a remote photoplethysmographic sensor
2019
Heart-rate estimation performed with remote photoplethysmography is a very active research field. Since pioneer works in 2010, which demonstrated the feasibility of the measure with low-grade consumers’ camera (webcam), the number of scientific publications have increased significantly in the domain. Hence, we observe a multiplication of the methods in order to retrieve the photoplethysmographic signal which hasled to an increased precision and quality of the heartrate estimation. Region of interest segmentation is a key step of the processing pipeline in order to maximize the quality of the measured signal. We propose a new method to perform remote photoplethysmographic measurement using a…
Left-Ventricle Segmentation of SPECT Images of Rats
2015
Single-photon emission computed tomography (SPECT) imaging of the heart is helpful to quantify the left-ventricular ejection fraction and study myocardial perfusion scans. However, these evaluations require a 3-D segmentation of the left-ventricular wall on each phase of the cardiac cycle. This paper presents a fast and interactive graph cut method for 3-D segmentation of the left ventricle (LV) of rats in SPECT images. The method is carried out in three steps. First, 3-D sampling of the LV cavity is made in a spherical-cylindrical coordinate system. Then, a graph-cut-based energy minimization procedure provides delineation of the myocardium centerline surface. From there, it is possible to…