Search results for "CARE"
showing 10 items of 9420 documents
Special Issue “Mental Health Issues and Quality of Life in Older Individuals”
2021
There are numerous biological, psychological, and social factors that have a more or less prominent impact on the mental health of older adults [...]
How can dementia and disability be prevented in older adults: where are we today and where are we going?
2021
Abstract Ageing of the population, together with population growth, has brought along an ample increase in the number of older individuals living with dementia and disabilities. Dementia is the main cause of disability in old age, and promoting healthy brain ageing is considered as a key element in diminishing the burden of age‐related disabilities. The World Health Organization recently launched the first risk reduction guidelines for cognitive impairment and dementia. According to recent estimates, approximately 40% of dementia cases worldwide could be attributable to 12 modifiable risk factors: low education; midlife hypertension and obesity; diabetes, smoking, excessive alcohol use, phy…
Is chocolate consumption associated with health outcomes? An umbrella review of systematic reviews and meta-analyses.
2019
Background & aims: The literature regarding the potential health benefits of chocolate consumption are unclear and the epidemiological credibility has not been systematically scrutinized, while the strength of the evidence is undetermined. We therefore aimed to map and grade the diverse health outcomes associated with chocolate consumption using an umbrella review of systematic reviews. Methods: Umbrella review of systematic reviews of observational and intervention studies (randomized placebo-controlled trials, RCTs). For each association, random-effects summary effect size, 95% confidence interval, and 95% prediction interval were estimated. We also assessed heterogeneity, evidence fo…
Análisis de la presencia de dietistas-nutricionistas en hospitales de Andalucía
2017
Introducción: La figura profesional de referencia en el tratamiento dietético en el ámbito hospitalario es el dietista-nutricionista (DN). Su interés público coincide con los datos sobre su actuación y eficiencia clínica. El objetivo es describir su presencia en hospitales públicos y privados de Andalucía y analizar en qué medida se cumplen los criterios de la Declaración de postura de la Asociación Española de Dietistas-Nutricionistas (AEDN) sobre la incorporación del DN en el Sistema Nacional de Salud de 2009.Material y métodos: Se seleccionó como muestra hospitales públicos y privados del Registro de Centros, Establecimientos y Servicios Sanitarios de la Consejería de Salud y Bienestar S…
Rapid detection of carbapenem resistance: Targeting a zero level of inadequate empiric antibiotic exposure
2016
Resistance to carbapenems is an increasingly encountered phenomenon in the ICU, complicating empiric and targeted antimicrobial therapy. Infections due to carbapenem-resistant microorganisms are characterized by high morbidity and mortality [1, 2]. Recently, there has been an increasing interest in rapid detection techniques, based on real time on-demand easy-to-use PCR, to detect genes responsible for carbapenem resistance. One of these techniques is the Cepheid Xpert Carba-R assay, which is able to detect and differentiate five of the most frequent genes associated with non-susceptibility to carbapenems in Gram-negative bacteria (bla KPC, bla VIM, bla OXA-48, bla IMP-1, bla NDM). The diag…
Consensus recommendation for a diagnostic guideline for acid sphingomyelinase deficiency
2017
Disclaimer: This diagnostic guideline is intended as an educational resource and represents the opinions of the authors, and is not representative of recommendations or policy of the American College of Medical Genetics and Genomics (ACMG). The information should be considered a consensus based on expert opinion, as more comprehensive levels of evidence were not available in the literature in all cases. Background: Acid sphingomyelinase deficiency (ASMD) is a rare, progressive, and often fatal lysosomal storage disease. The underlying metabolic defect is deficiency of the enzyme acid sphingomyelinase that results in progressive accumulation of sphingomyelin in target tissues. ASMD manifests…
Perfiles de resistencia y factores de riesgo de microorganismos resistentes en bacteriemia de origen abdominal
2017
Resumen Objetivo La presencia de microorganismos resistentes es una causa importante de fallo en el tratamiento antimicrobiano inicial. Los objetivos de este estudio son conocer el perfil de resistencia de los microorganismos causantes de bacteriemia de origen abdominal e identificar si el uso previo de antibioticos y el lugar de adquisicion de la bacteriemia son factores de riesgo para determinar la presencia de microorganismos resistentes. Material y metodo Se diseno un estudio de cohorte retrospectiva de todos los pacientes adultos que presentaron bacteriemia y/o fungemia cuyo foco infeccioso primario fue de origen abdominal ingresados en un hospital universitario durante los anos 2011-2…
Análisis de casos de candidemia por Candida auris en una Unidad de Cuidados Intensivos de Anestesia en un hospital terciario
2021
Resumen Candida auris es una levadura emergente multirresistente. Objetivos Analizar la relacion entre la existencia de colonizacion por C. auris y la aparicion de candidiasis invasora. Descripcion de la muestra de pacientes colonizados, factores de riesgo para colonizacion y/o infeccion y calculo de las tasas de mortalidad. Metodologia Estudio observacional longitudinal en una Unidad de Cuidados Intensivos de Anestesia durante el ano 2018. Resultados Ingresaron 2.130 pacientes; 124 pacientes tuvieron estudios de vigilancia positivos, 118 casos fueron colonizacion cutanea y 52 faringea. Se identificaron los pacientes con hemocultivo positivo. Se encontro asociacion estadisticamente signific…
Immunization against Hepatitis B Surface Antigen (HBsAg) in a Cohort of Nursing Students Two Decades after Vaccination: Surprising Feedback
2019
Health-care students can be exposed to biological risks during university training. The persistence of long-term immunogenicity against hepatitis B virus (HBV) was analyzed in a cohort of nursing students two decades after primary vaccination. A total of 520 students were enrolled at the University of Palermo and were evaluated for levels of anti-HBsAg antibodies. The students were examined during the first year of their Degree Course and were checked two years later. All students with anti-HBsAg <
Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatri…
2017
Heritable predisposition is an important cause of cancer in children and adolescents. Although a large number of cancer predisposition genes and their associated syndromes and malignancies have already been described, it appears likely that there are more pediatric cancer patients in whom heritable cancer predisposition syndromes have yet to be recognized. In a consensus meeting in the beginning of 2016, we convened experts in Human Genetics and Pediatric Hematology/Oncology to review the available data, to categorize the large amount of information, and to develop recommendations regarding when a cancer predisposition syndrome should be suspected in a young oncology patient. This review su…