Search results for "CONDENSATION"
showing 10 items of 468 documents
Facile Preparation of 3-Amino-4-(arylamino)-1H-isochromen-1-ones by a New Multicomponent Reaction
2005
Reactions between 2-formylbenzoic acid, various anilines and HCN result in the formation of 3-amino-4-(arylamino)-1H-isochromen-1-ones in high yield. The mechanism of this three-component condensation involves the intermediate formation of an α-aminonitrile and subsequent cyclization through nucleophilic attack of the ortho-carboxylate at the nitrile carbon. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)
An Unexpected Three-Component Condensation Leading to Amino(3-oxo-2,3-dihydro-1H-isoindol-1-ylidene)acetonitriles.
2005
The reaction of 2-carboxybenzaldehyde with primary amines in the presence of cyanide leads to the formation of 2-substituted amino(3-oxo-2,3-dihydro-1H-isoindol-1-ylidene)acetonitriles. These compounds originate from the condensation of 2-carboxybenzaldehyde with the amine and two molecules of hydrogen cyanide and represent a novel class of isoindolinones.
Regio- and diastereoselective condensation of resorcarenes with primary amines and formaldehyde
1995
Abstract Mannich reactions of resorcarenes 1 with chiral amines yield single diastereomeric tetrakis-(benzodihydro-1,3-oxazine) derivatives 2 in high yields (80–90%). Epimerisation of these products occurs in the presence of acid.
Antidiabetische wirkstoffe. III. 4,5,6-Trisubstituierte 2-(4-toluidino)pyrimidine
1984
Aus der Kondensation von 4-Tolylguanidin (1) mit den β-Diketonen 2a-b gehen die 2-(4-Toluidino)pyrimidine 3a-b hervor. The condensation of 4-tolyiguanidine (1) with the β-kiketones 2a-b yields the 2-(4-toluidino)pyrimidines 3a-b.
Trichomonazide Wirkstoffe, 2. Mitt. Verzweigtkettig 4,6-disubstituierte 2-Cyanaminopyrimidine
1985
Aus der Umsetzung von Dicyandiamid (1) mit den β-Diketonen 2a–b gehen die 4,6-verzweigtkettig disubstituierten 2-Cyanaminopyrimidine 3a–b hervor. Fur Strukturtyp 3 last sich aus den spektroskopischen Daten, speziell aus den 1H- und 13C-NMR-Werten, das Vorliegen eines Gleichgewichts zwischen den tautomeren 2-Cyanamino- und 2-Cyaniminopyrimidinformen ableiten. 3 zeichnet sich durch trichomonazide, antivirale und antimykotische Wirkung aus. Trichomonacidal Agents, II: 4,6-Disubstituted 2-(Cyanoamino)pyrimidines Carrying Branched Substituents The reaction of dicyandiamide (1) with the β-diketones 2a–b yields the 4,6-branched disubstituted 2-(cyanoamino)pyrimidines 3a–b. From spectroscopic evide…
A Photochemical One-Pot Three-Component Synthesis of Tetrasubstituted Imidazoles
2014
Tetrasubstituted imidazoles can be formed in a photochemical one-pot synthesis from aldehydes, α-aminonitriles, and isoxazoles. Condensation of the first two components produces α-(alkylideneamino)nitriles which react under basic conditions with the acylazirines formed in situ by photochemical ring transformation of the isoxazole component. This process includes an unusual cleavage of the C(2)-C(3) bond of the acylazirine. The reaction mechanism was studied by DFT calculations.
On the reactions between ethyl benzoylacetate and anisidines
1975
4-Hydroxy-7-methoxy-3-[(m-methoxyphenylimino)-phenylmethyl]-2-quinolone (6) was a by-product of the condensation of ethyl benzoylacetate and m-anisidine; no corresponding products were obtained from p- and o-anisidine. From o-anisidine, 2-phenyl-8-methoxy-4-quinolone (1c) was isolated and characterized; the same reaction also gave 2-phenyl-4-o-anisidyl-1-8-methoxy-quinoline (11) and the Schiff base (14) as by-products; the crotonamide (15) also isolated, is a possible intermediate of the cyclization. The direct condensation of anisidines with ethyl benzoylacetate in diphenyl ether and the transformations of some intermediates were studied.
ChemInform Abstract: FeCl3·6H2O-Catalyzed Mukaiyama-Aldol Type Reactions of Enolizable Aldehydes and Acetals.
2015
A general procedure for the title condensation of dimethylacetals derived from enolizable aldehydes with silyl enol ethers is developed using FeCl3 as the catalyst.
Surfactant controlled preparation of mesostructured transition-metal oxide compounds
1994
The use of surfactants as templates allows the synthesis of mesostructured transition-metal oxides by a cooperative, interface controlled condensation process.
Attempted preparation of trisphenol-II
1998
Abstract Condensation of 4,4-bis-(4-methoxyphenyl)-2-methyl-2-pentanol with phenol, in the presence of hydrogen chloride, gives 1,3,3-trimethyl-1-(4-methoxyphenyl)-5-methoxyindan and tris-(4-methoxyphenyl)-ethane instead of expected 2,2,4-tris-(4-methoxyphenyl)-4-methylpentane (trisphenol-II). tris-(4-Hydroxyphenyl)-ethane was obtained, together with bisphenol-A, by condensation of phenol with acetylacetone.