Search results for "CONSOLIDATION"

2020

Learning to associate written letters with speech sounds is crucial for the initial phase of acquiring reading skills. However, little is known about the cortical reorganization for supporting letter-speech sound learning, particularly the brain dynamics during the learning of grapheme-phoneme associations. In the present study, we trained 30 Finnish participants (mean age: 24.33 years, SD: 3.50 years) to associate novel foreign letters with familiar Finnish speech sounds on two consecutive days (first day ​~ ​50 ​min; second day ​~ ​25 ​min), while neural activity was measured using magnetoencephalography (MEG). Two sets of audiovisual stimuli were used for the training in which the graphe…

L'intonaco Li Vigni nell'architettura del XX secolo a Palermo. Nuove conoscenze e applicazioni diagnostiche per la manutenzione

2013

Il saggio presenta lo studio degli intonaci formulati per imitare le pietre e i marmi naturali che si diffondono in Sicilia all’inizio del XX secolo ed evidenzia che le prime applicazioni e la diffusione delle nuove malte, anche nel resto dell’Italia, risentono delle sperimentazioni condotte in tutta l’Europa. Il contributo riassume i risultati di una rigorosa e capillare ricognizione tra i brevetti conservati presso l’Archivio Centrale dello Stato a Roma inerenti alle malte per il confezionamento dell’intonaco a “finta pietra”, ne analizza i contenuti in modo critico e pone in risalto i contatti culturali con le sperimentazioni dei materiali in atto nell’ambito dei grandi cantieri di resta…

Spatial learning and expression patterns of PP1 mRNA in mouse hippocampus.

2009

<i>Background:</i> Synaptic plasticity is believed to be the major cellular basis for learning and memory. Protein phosphorylation is a key process involved in changes in the efficacy of neurotransmission. In long-term changes synaptic plasticity is followed by structural plasticity and protein de novo synthesis. Such mechanisms are believed to build the basis of hippocampal learning and memory investigated in the Morris water maze (MWM) task. To examine the role of dephosphorylation during that model for spatial learning, we analyzed protein phosphatase 1 (PP1) expression in the hippocampus of mice at various stages of the task and in two groups with different learning abilitie…

Rapid nucleus-scale reorganization of chromatin in neurons enables transcriptional adaptation for memory consolidation

2020

AbstractThe interphase nucleus is functionally organized in active and repressed territories defining the transcriptional status of the cell. However, it remains poorly understood how the nuclear architecture of neurons adapts in response to behaviorally relevant stimuli that trigger fast alterations in gene expression patterns. Imaging of fluorescently tagged nucleosomes revealed that pharmacological manipulation of neuronal activity in vitro and auditory cued fear conditioning in vivo induce nucleus-scale restructuring of chromatin within minutes. Furthermore, the acquisition of auditory fear memory is impaired after infusion of a drug into auditory cortex which blocks chromatin reorganiz…

Structural Uses of Stone and Timber in The European Historical Construction

2018

This paper investigates the stone masonry with timber reinforcement through Europe. It is a remarkable practice, either historical and contemporary, consisting of combining different materials to build up a masonry. This technology shows a wide variety of typological, formal, and technological types of buildings across Europe as it is strongly influenced by the nature and availability of local materials, the cultural aspects of the various communities, and the soils geological nature. As a consequence, the same constructive typology is based on different premises and leads to many interesting results. In this paper the various uses of such a mixed stone-timber masonry are shown in relation …

Co‐parenting through subsidiaries: A model of value creation in the multinational firm

2017

Research summary We analyze a novel way to configure and manage multinational networks and propose a model of "co-parenting", characterized by the sharing of parenting roles and distribution of responsibilities between two units. We develop our argument around the notion of the springboard subsidiary, an operating subsidiary which assumes headquarters’ functions since it shares greater institutional closeness with both the headquarters’ country as well as with the host region. Based upon qualitative data, our inductive model revolves around three stages: establishment, consolidation and maturity, each of which reflects distinct roles and loci of decision making among the three actors involv…

Development Studies in Tanzania: Historical Trajectory and Future Visions

2018

The chapter discusses the history, dilemmas and future visions of Development Studies in Tanzania, especially from the perspective of Institute of Development Studies in the University of Dar es Salaam. It shows how in the 1970s Development Studies played a significant role in the consolidation of state ideology of African socialism among university students, and since then, has gradually evolved into a recognized discipline with MA and PhD programmes. Over the years, the discipline has dealt with dilemmas related to its multidisciplinary nature, state ideologies, international donor agendas and the changing demands concerning academic publications. Recently, Development Studies in Tanzania…

Consolidation of waterlogged woods by in-situ polymerisation of isoeugenol

2008

Hydrological Analysis of Loess Plateau Highland Control Schemes in Dongzhi Plateau

2020

Gully Consolidation and Highland Protection (GCHP) Project is a major soil and water conservation and land remediation project implemented in the Chinese Loess Plateau (CLP). As the connection between the mechanisms of erosion and practical applications for addressing it is not clear, the implementation of engineering measures to combat the problem has been insufficient to date. This study used field investigation and descriptive statistics, together with hydrological analysis modeling to gain an understanding of the impact of the Loess Plateau Highland Control Schemes on the evolution of the Dongzhi Plateau as the largest, most well-preserved, and the thickest loess deposit region in China…

Bio-inspired consolidants derived from crystalline nanocellulose for decayed wood

2018

Abstract Novel bio-inspired materials derived from crystalline nanocellulose (CNC) have been tested as wood consolidants. A suspension of CNC, produced by acid hydrolysis of cellulose and used as such or mixed with lignin and/or siloxane derivatives (PDMS), was applied on rotted wood samples of Norway spruce. X-Ray diffraction analysis on CNC powder showed high crystallinity index. Dynamic light scattering (DLS) measurement indicated a nearly uniform particle size distribution with an average hydrodynamic diameter for pure CNC smaller than that in the mixtures. Raman and FTIR spectroscopies suggested interactions between lignin, PDMS and CNC components. The storage modulus of wood samples, …