Search results for "Cancer screening"
showing 10 items of 73 documents
Frequentist and Bayesian approaches for a joint model for prostate cancer risk and longitudinal prostate-specific antigen data
2015
The paper describes the use of frequentist and Bayesian shared-parameter joint models of longitudinal measurements of prostate-specific antigen (PSA) and the risk of prostate cancer (PCa). The motivating dataset corresponds to the screening arm of the Spanish branch of the European Randomized Screening for Prostate Cancer study. The results show that PSA is highly associated with the risk of being diagnosed with PCa and that there is an age-varying effect of PSA on PCa risk. Both the frequentist and Bayesian paradigms produced very close parameter estimates and subsequent 95% confidence and credibility intervals. Dynamic estimations of disease-free probabilities obtained using Bayesian infe…
Krūts vēža attīstība Latvijā pēc valsts krūts vēža skrīninga programmas ieviešanas
2020
Latvijā sieviešu saslimstība un mirstība no krūts vēža ieņem pirmo vietu starp visiem ļaundabīgiem audzējiem. Katru gadu saslimšana tiek pirmreizēji reģistrēta aptuveni 1100 pacientēm un ikgadu no krūts vēža mirst vairāk nekā 400 sievietes. Kopš 2009. gadā Latvijā darbojas valsts krūts vēža skrīnings ar mērķi uzlabot krūts vēža agrīnu diagnostiku, tomēr vidēji 32 % gadījumos krūts vēzis tiek diagnosticēts novēloti slimības III un IV stadijā (SPKC, 2017). Darba tēma ir aktuāla un darba rezultāti ļauj sniegt rekomendācijas agrīnas diagnostikas uzlabošanai un skrīninga programmas uzlabošanai. Darba mērķis: veikt Latvijas valsts apmaksāta krūšu skrīninga efektivitātes izpēti laika posmā no 2010…
Computerunterstützte Diagnostik in der Thoraxradiologie - aktuelle Schwerpunkte und Techniken
2003
The proliferation of digital data sets and the increasing amount of images, e. g. through the use of multislice spiral CT or multiple follow-up examinations in the context of new therapies, are ideal prerequisites for computer-aided diagnosis (CAD) in chest radiology. Multiple studies have described the applications and advantages of computer assistance in performing different diagnostic tasks. More powerful computers will enable the introduction of these systems into the clinical routine and could provide an enormous increase in morphological and functional information. The commercial introduction of tools for detection and visualization of pulmonary nodules has already begun. This is one …
“The risk of age”? Early detection test, prostate cancer and practices of self
2010
Abstract Drawing on Rose and Novas’s concept of “biological citizenship” and Michel Foucault's "practices of self", this paper reflects on how men become agents of their own therapeutic regimens, and yet internalise messages of risk and practices of self within early detection of prostate cancer discourses in the late 20th century. In doing so, it traces the ways in which concepts of age, gender and risk converge at the problematic site of prostate cancer and preventative health strategies, both of the state and the medical profession. Analysing how insecurities have simultaneously resulted in over-promoting and over-diagnosing risk, thereby blurring the lines between normal and pathologica…
Breast cancer screening programmes: Challenging the coexistence with opportunistic mammography.
2014
Abstract Objective This study investigated predictive factors of women's participation in organized mammography screening (OrgMS) and/or opportunistic mammography screening (OppMS) when the two screening modes coexist. Methods Questionnaires were sent to 6,000 women aged 51–74 years old invited to attend an OrgMS session between 2010 and 2011 in France. Data collected concerned the women's healthcare behaviour and their socioeconomic characteristics. Women without a personal or family history of breast cancer that could explain their participation in OppMS were retained in the generalized logits analysis. Results The data of 1,202 women were analysed. Of these, 555 (46.2%) had attended OrgM…
Physical exercise program, a strategy to prevent cardiotoxicity in early breast cancer: A literature review
2018
Breast cancer, the most common in women, is a cancer of good prognosis. During this last decade, the improvement of cancer screening and treatment has significantly increased disease-free and overall survival. However, the chemotherapy, especially based on anthracyclines, and targeted therapies like trastuzumab have a toxicity to the cardiovascular system. If physical exercise is recognized as beneficial in tertiary prevention, especially by reducing fatigue, improving the physiological capacities of exercise, muscle strength and ultimately quality of life, conversely, few data are available on the effects of exercise on treatment-induced cardiotoxicity. This review, based on the PubMed dat…
Risk of digestive cancers in a cohort of 69 460 five-year survivors of childhood cancer in Europe: the PanCareSurFup study.
2021
BackgroundSurvivors of childhood cancer are at risk of subsequent primary neoplasms (SPNs), but the risk of developing specific digestive SPNs beyond age 40 years remains uncertain. We investigated risks of specific digestive SPNs within the largest available cohort worldwide.MethodsThe PanCareSurFup cohort includes 69 460 five-year survivors of childhood cancer from 12 countries in Europe. Risks of digestive SPNs were quantified using standardised incidence ratios (SIRs), absolute excess risks and cumulative incidence.Results427 digestive SPNs (214 colorectal, 62 liver, 48 stomach, 44 pancreas, 59 other) were diagnosed in 413 survivors. Wilms tumour (WT) and Hodgkin lymphoma (HL) survivors…
Proposal for an Alliance Between Healthcare and Legal Area Professionals for Shared Public Health and Preventive Strategies in Italy and Europe
2020
Following the implementation of the new Italian legislation on responsibility of healthcare workers, a multi-professional framework, involving representatives of the Italian public health professionals and legal professionals expert in the field, drafted a proposal of the actionable recommendations to be implemented in the management of civil and penal disputes arising from the practice of public health interventions. In order to prevent legal disputes concerning some public health fields such as vaccinations, cancer screening, environmental health surveillance, and hospital management, it should be primary taken into account to update guidelines in supporting decision-making processes, in …
Implementation of gastric cancer screening - the global experience.
2014
Gastric cancer (GC) is still an important global healthcare problem, and in absolute figures it is going to remain at the present level in foreseeable future. In general, survival of patients with GC is poor mainly due to advanced-stage diagnosis. Early-stage GC can be cured by endoscopic resection or less invasive surgical treatment. Unfortunately, there is no appropriate screening strategy available for global application. This article provides a description of established national and regional GC screening programs and the screening modalities used. This review also summarizes current approaches to develop cancer-screening biomarkers. Although candidates with initial promising results ha…
European guidelines for quality assurance in colorectal cancer screening and diagnosis: Overview and introduction to the full Supplement publication
2013
Population-based screening for early detection and treatment of colorectal cancer (CRC) and precursor lesions, using evidence-based methods, can be effective in populations with a significant burden of the disease provided the services are of high quality. Multidisciplinary, evidence-based guidelines for quality assurance in CRC screening and diagnosis have been developed by experts in a project co-financed by the European Union. The 450-page guidelines were published in book format by the European Commission in 2010. They include 10 chapters and over 250 recommendations, individually graded according to the strength of the recommendation and the supporting evidence. Adoption of the recomme…