Search results for "Caprifoliaceae"

showing 7 items of 7 documents

Phytochemistry of Weigela x "kosteriana variegata" (Caprifoliaceae)

2018

International audience; One new triterpene glycoside 3-O-beta-D-xylopyranosyl-(1 -> 4)-[beta-D-glucopyranosyl-(1 -> 3)]-beta-D-xyl opyranosyl-(1 -> 4)-beta-D-xylopyranosyl-(1 -> 3)-alpha-L-rhamnopyranosyl-(1 -> 2)-alpha-L-arabinopyranosyloleanolic acid, was isolated from Weigela x "kosteriana variegata" (Caprifoliaceae), with three known ones. Their structures were characterized by a combination of mass spectrometry and 1D and 2D NMR spectrocopic techniques including H-1- and C-13 NMR, COSY, TOCSY, NOESY, HSQC, and HMBC experiments. The toxicological properties of some glycosides were determined with a zebrafish-based assay. The results show that the most active compounds were toxic to the …

[SDV.AEN] Life Sciences [q-bio]/Food and NutritionWeigela x "kosteriana variegata"[SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/PharmacologyZebrafish-based assay[SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/PharmacologyOleanolic acid glycosides2D NMR[SDV.AEN]Life Sciences [q-bio]/Food and NutritionCaprifoliaceae
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<p><strong>Lectotypification of six names of species of <em>Scabiosa</em> s.l. (Caprifoliaceae) endemic to North Africa and r…

2020

As part of an ongoing project for the investigation of the Algerian-Tunisian flora, six names of species of Caprifoliaceae subfam. Dipsacaceae, endemic to central and western North Africa, described in the 19th and 20th Centuries under the genus Scabiosa, are here lectotypified. They are: Scabiosa camelorum Cosson & Durieu, Scabiosa cartenniana Pons & Quézel, Scabiosa daucoides Desf., Scabiosa farinosa Cosson, Scabiosa parielii Maire, and Scabiosa robertii Barratte. Taxonomic notes, distributisson and new unpublished data about plant phenology of these taxa are given.

FloraTaxonbiologyGenusBotanyNorth africaScabiosaPlant Sciencebiology.organism_classificationPlant phenologyCaprifoliaceaeDipsacaceaeEcology Evolution Behavior and SystematicsPhytotaxa
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Oleanolic acid and hederagenin glycosides from Weigela stelzneri

2015

Four previously undescribed and one known oleanolic acid glycosides were isolated from the roots of Weigela stelzneri, and one previously undescribed and three known hederagenin glycosides were isolated from the leaves. Their structures were elucidated mainly by 2D NMR spectroscopic analysis and mass spectrometry as 3-O-β-D-glucopyranosyl-(1 → 2)-[β-D-xylopyranosyl-(1 → 4)]-β-D-xylopyranosyl-(1 → 4)-β-D-xylopyranosyl-(1 → 3)-α-L-rhamnopyranosyl-(1 → 2)-α-L-arabinopyranosyloleanolic acid, 3-O-β-D-glucopyranosyl-(1 → 2)-[β-D-xylopyranosyl-(1 → 4)]-β-D-xylopyranosyl-(1 → 4)-β-D-xylopyranosyl-(1 → 3)-α-L-rhamnopyranosyl-(1 → 2)-β-D-xylopyranosyloleanolic acid, 3-O-β-D-glucopyranosyl-(1 → 2)-[β-…

LipopolysaccharidesWeigelaStereochemistryInterleukin-1betaStereoisomerismTumor cellsPlant ScienceHorticultureCaprifoliaceaePlant Roots01 natural sciencesBiochemistrychemistry.chemical_compoundGlycosidesOleanolic AcidNuclear Magnetic Resonance BiomolecularMolecular BiologyOleanolic acidchemistry.chemical_classificationDose-Response Relationship DrugLow toxicitybiology010405 organic chemistryGlycosideStereoisomerismGeneral Medicinebiology.organism_classification0104 chemical sciencesPlant Leaves010404 medicinal & biomolecular chemistryHederageninchemistryTwo-dimensional nuclear magnetic resonance spectroscopyPhytochemistry
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Cytotoxic glycosides from the roots of Weigela x “Bristol Ruby”

2019

International audience; Seven oleanane-type glycosides were extracted and isolated by various chromatographic methods from the roots of Weigela x "Bristol Ruby" (1-7), six previously undescribed (1-6) and a known one (7). Their structures were assigned by spectroscopic analysis mainly 2D NMR and mass spectrometry (ESIMS). Selected triterpenoid glycosides (1-3, 6, 7) displayed a good cytotoxic activity against a mouse colon cancer cell line CT26.

WeigelaCytotoxicityPhytochemicalsOleanolic acid glycosidesMass spectrometryPlant Roots01 natural sciencesCaprifoliaceaeMiceTriterpenoidCell Line TumorDrug Discovery[SDV.IDA]Life Sciences [q-bio]/Food engineeringAnimalsCytotoxic T cellGlycosidesOleanolic AcidCytotoxicityCaprifoliaceaePharmacologychemistry.chemical_classificationChromatographyMolecular Structurebiology010405 organic chemistryGlycosideGeneral MedicineWeigela x “Bristol Ruby”biology.organism_classificationAntineoplastic Agents PhytogenicTriterpenesNMR3. Good health0104 chemical sciences010404 medicinal & biomolecular chemistrychemistryTwo-dimensional nuclear magnetic resonance spectroscopy
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Oleanane-type glycosides from the roots of Weigela florida “rumba” and evaluation of their antibody recognition

2018

Three triterpene glycosides were isolated from the roots of Weigela florida "rumba" (Bunge) A. DC.: two previously undescribed 3-O-β-d-xylopyranosyl-(1→2)-[β-d-xylopyranosyl-(1→4)]-β-d-xylopyranosyl-(1→4)-β-d-xylopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-l-arabinopyranosyloleanolic acid (1) and 3-O-β-d-xylopyranosyl-(1→2)-[β-d-glucopyranosyl-(1→4)]-β-d-xylopyranosyl-(1→4)-β-d-xylopyranosyl-(1→3)-α-l-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyloleanolic acid (2), and one isolated for the first time from a natural source 3-O-β-d-xylopyranosyl-(1→3)-α-l-rhamnopyranosyl-(1→2)-α-l-arabinopyranosyloleanolic acid (3). Their structures were elucidated mainly by 2D NMR spectroscopic analysis (COSY, …

0301 basic medicineMultiple SclerosisStereochemistryEnzyme-Linked Immunosorbent AssayCaprifoliaceaePlant Roots01 natural sciences03 medical and health scienceschemistry.chemical_compoundTriterpeneDrug DiscoveryHumansGlycosidesOleanolic AcidCaprifoliaceaeOleanolic acidOleananePharmacologychemistry.chemical_classificationMolecular Structurebiology010405 organic chemistryGlycosideGeneral Medicinebiology.organism_classification0104 chemical sciences030104 developmental biologyImmunoglobulin MchemistryImmunoglobulin Mbiology.proteinAntibodyTwo-dimensional nuclear magnetic resonance spectroscopyFitoterapia
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Polyphenols pattern and correlation with antioxidant activities of berries extracts from four different populations of SicilianSambucus nigraL.

2014

Sambucus nigra L. (Caprifoliaceae) is wide spread in temperate and sub-tropical zones. The consumption of its berries has been associated with health benefits especially for its high content of natural antioxidants such as polyphenols, in particular anthocyanins. In this work we investigated the polyphenolic composition and the in vitro antioxidant activities (ABTS, DPPH, BCB and FRAP-ferrozine (FRAP-FZ) assays) of S. nigra berries, collected in four different Sicilian areas (Italy). Elderberries are considered one of the fruits with highest anthocyanins content, the amount of phenolic compounds, other than anthocyanins, is approximately 1.5 times greater than the latter. The LC–MS analyses…

AntioxidantSettore AGR/05 - Assestamento Forestale E SelvicolturaDPPHmedicine.medical_treatmentantioxidant activityPlant ScienceSambucus nigraBiochemistryAntioxidantsAnalytical ChemistryAnthocyaninschemistry.chemical_compoundSambucus nigrapolyphenolic compositionBotanymedicineSambucus nigra berries polyphenolic composition antioxidant activitySettore BIO/15 - Biologia FarmaceuticaFood scienceCaprifoliaceaeChromatography High Pressure LiquidABTSMolecular StructurebiologyChemistryOrganic ChemistryPolyphenolsSettore CHIM/06 - Chimica Organicabiology.organism_classificationlanguage.human_languageItalySambucusPolyphenolFruitlanguageComposition (visual arts)Oxidation-ReductionSicilianberrieNatural Product Research
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Phytochemistry of Weigela x “kosteriana variegata” (Caprifoliaceae)

2018

One new triterpene glycoside 3- O-β-D-xylopyranosyl-(1→4)-[β-D-glucopyranosyl-(1→3)]-β-D-xylopyranosyl-(1→4)-β-D-xylopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyloleanolic acid, was isolated from Weigela x “kosteriana variegata” (Caprifoliaceae), with three known ones. Their structures were characterized by a combination of mass spectrometry and 1D and 2D NMR spectrocopic techniques including 1H- and 13C NMR, COSY, TOCSY, NOESY, HSQC, and HMBC experiments. The toxicological properties of some glycosides were determined with a zebrafish-based assay. The results show that the most active compounds were toxic to the larvae in the range of 1 μM.

Pharmacologychemistry.chemical_classificationWeigelaPhytochemistrybiology010405 organic chemistryStereochemistryGlycosidePlant ScienceGeneral MedicineCarbon-13 NMRbiology.organism_classification01 natural sciences0104 chemical sciences010404 medicinal & biomolecular chemistryComplementary and alternative medicineTriterpenechemistryDrug DiscoveryCaprifoliaceaeTwo-dimensional nuclear magnetic resonance spectroscopyHeteronuclear single quantum coherence spectroscopyNatural Product Communications
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