Search results for "Case"

showing 10 items of 3855 documents

Splenic lymphangiomatosis showing rapid growth during lactation: a case report.

2010

Splenic lymphangiomatosis is a very rare condition that, from 1990 to date, has been described only nine times. In the present report, we describe the first case of splenic lymphangiomatosis with rapid growth during lactation in a 35-year-old woman. We also underline the difficultly in making an accurate preoperative diagnosis, despite more modern imaging techniques. Total splenectomy was considered to be the treatment needed, both to make a definitive diagnosis and to exclude the presence of malignancy.

Adultmedicine.medical_specialtymedicine.medical_treatmentBiopsySplenectomySplenic NeoplasmCase ReportMalignancyPredictive Value of TestsLactationLymphangiomaBiopsyLymphangiomatosiMedicineHumansLactationLymphangiomatosismedicine.diagnostic_testLymphangiomabusiness.industrySplenic NeoplasmsGastroenterologyGeneral Medicinemedicine.diseaseSurgerymedicine.anatomical_structureTreatment OutcomePredictive value of testsDisease ProgressionSplenectomyFemalebusinessTomography X-Ray ComputedSpleen
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Genetic polymorphisms of serotonin transporter and receptor 1A could influence success during embryo implantation and maintenance of pregnancy

2012

Objective To explore whether serotonin-related gene polymorphisms influence clinical outcomes of IVF treatment in recipients using donated oocytes. Design Nested case-control study. Setting University-affiliated infertility clinic. Patient(s) Two hundred forty-five women undergoing IVF treatment with donated oocytes. Intervention(s) None. Main Outcome Measure(s) Genotype and haplotype analysis of the serotonin transporter-linked polymorphic region (5-HTTLPR), rs1800532, rs6295, rs6313, and rs3813929, between recipients grouped according to the results of the oocyte donation for IVF treatment. Result(s) No differences were found between genotype distribution of the tryptophan hydroxylase 1, …

Adultmedicine.medical_specialtymedicine.medical_treatmentEarly Pregnancy LossFertilization in VitroPolymorphism Single NucleotideAndrologyGene FrequencyPregnancyRisk FactorsInternal medicineGenotypeOdds RatiomedicineHumansEmbryo ImplantationSerotonin transporterSerotonin Plasma Membrane Transport ProteinsAnalysis of VariancePregnancyChi-Square DistributionIn vitro fertilisationOocyte DonationbiologyHaplotypeObstetrics and GynecologyEmbryo Transfermedicine.diseaseEmbryo transferAbortion SpontaneousPregnancy rateLogistic ModelsPhenotypeTreatment OutcomeEndocrinologyHaplotypesReproductive MedicineCase-Control StudiesReceptor Serotonin 5-HT1Abiology.proteinFemaleFertility and Sterility
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Role of interleukin-4 in pathogenesis of oral lichen planus : a systematic review

2020

Background Oral lichen planus (OLP) is a premalignant mucocutaneous disease that affects 1-2% of the adult population. Immunological factor may act as etiological factor. The cellular immune cells such as T cells are important in pathogenesis of OLP. Interleukin-4 (IL-4) is secreted by T-helper 2 (Th2). Several studies have been carried out on the role of IL-4 in OLP. The aim of this study was to review the level of IL-4 in OLP, effective factors in the production of IL-4 and its role in the development of OLP. Material and Methods A search in PubMed was performed on the literature published from 2000 until august 2019 using the following keywords: “oral lichen planus” or “OLP” and “interle…

Adultmedicine.medical_specialtymedicine.medical_treatmentMucocutaneous zoneDiseaseReviewPathogenesisstomatognathic systemmedicineHumansGeneral DentistryInterleukin 4Oral Medicine and Pathologybusiness.industryCase-control studymedicine.disease:CIENCIAS MÉDICAS [UNESCO]Dermatologystomatognathic diseasesCytokineOtorhinolaryngologyCase-Control StudiesUNESCO::CIENCIAS MÉDICASEtiologyCytokinesSurgeryOral lichen planusInterleukin-4businessPrecancerous ConditionsLichen Planus Oral
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Posturographic analysis of balance control in patients with haemophilic arthropathy

2007

Summary.  Musculoskeletal disorders in haemophiliacs represent the highest percentage of lesions, giving rise to haemophilic arthropathy (HA) which predominantly affects lower limbs, influencing postural control, standing and walking. Leading a sedentary lifestyle seems to influence strength and muscular resistance in haemophiliacs which, in turn, are related to articular stability and the prevention of articular degenerative processes. The objective of this work was to study alterations in balance to subsequently evaluate the appropriate therapeutics and how this influences the development of arthropathy. Twenty-five haemophiliacs with HA, 25 haemophiliacs without HA (NHA) and 25 healthy c…

Adultmedicine.medical_specialtymedicine.medical_treatmentPosturePhysical exerciseHemophilia AHaemophiliaPhysical medicine and rehabilitationHemarthrosisArthropathymedicineHumansForce platformPhysical ExaminationPostural BalanceGenetics (clinical)Balance (ability)Sedentary lifestyleAnalysis of VarianceHaemophilic arthropathyRehabilitationbusiness.industryHematologyGeneral Medicinemedicine.diseaseCase-Control StudiesPhysical therapybusinessHaemophilia
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No phenotypic differences for polycystic ovary syndrome (PCOS) between women with and without type 1 diabetes mellitus.

2013

Context: Women with type 1 diabetes mellitus (DM1) have a higher prevalence of polycystic ovary syndrome (PCOS) than the general population. Objective: The aim of this study was to clarify, in DM1 women with PCOS(PCOS-DM1), the influence of insulin therapy and glycemic control and evaluate the hormonal and phenotypic differences with age-matched and body mass index (BMI)-matched women with PCOS without diabetes. Design, Setting, and Patients: We evaluated 103 DM1 women with and without PCOS treated with intensive insulin therapy; 38 age-matched and BMI-matched women with PCOS without diabetes were compared in a cross-sectional study. Outcome Measurements: Clinical, anthropometric, and metab…

Adultmusculoskeletal diseasesPCOS Type 1 Diabetescongenital hereditary and neonatal diseases and abnormalitiesmedicine.medical_specialtyAdolescentendocrine system diseasesEndocrinology Diabetes and Metabolismmedia_common.quotation_subjectClinical BiochemistryPopulationContext (language use)BiochemistryBody Mass IndexSettore MED/13 - EndocrinologiaYoung AdultEndocrinologyInternal medicineDiabetes mellitusPrevalencemedicineHumanseducationReproductive HistoryMenstrual cyclemedia_commoneducation.field_of_studyType 1 diabetesbusiness.industryPolycystic ovary syndrome (PCOS)Biochemistry (medical)nutritional and metabolic diseasesmedicine.diseasePolycystic ovaryfemale genital diseases and pregnancy complicationsCross-Sectional StudiesDiabetes Mellitus Type 1PhenotypeEndocrinologyCase-Control StudiesFemalebusinessBody mass indexPolycystic Ovary Syndrome
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Late onset of unilateral optic disk edema secondary to treatment with imatinib mesylate

2017

Key Clinical Message Prompt ophthalmology evaluation and immediate imatinib suspension should be suggested at any time of tyrosine kinase inhibitor therapy in patients with visual deficit, as it may be a clinical manifestation of optic disk edema, and suspension may help in prompt recovery.

Adverse event0301 basic medicinegenetic structuresmedicine.drug_classOptic Disk EdemaLate onsetCase ReportClinical manifestationCase ReportsTyrosine-kinase inhibitor03 medical and health sciences0302 clinical medicinechronic myeloid leukemiatyrosine kinase inhibitorsmedicineIn patientAdverse effectbusiness.industryoptic disk edemaImatinibGeneral Medicineeye diseases030104 developmental biologyImatinib mesylateimatiniboptic nerve edemaAnesthesiaAdverse events030221 ophthalmology & optometrybusinessmedicine.drugClinical Case Reports
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Childhood Maltreatment, Educational Attainment, and IQ: Findings From a Multicentric Case-control Study of First-episode Psychosis (EU-GEI).

2022

[Background and hypothesis] Evidence suggests that childhood maltreatment (ie, childhood abuse and childhood neglect) affects educational attainment and cognition. However, the association between childhood maltreatment and Intelligence Quotient (IQ) seems stronger among controls compared to people with psychosis. We hypothesised that: the association between childhood maltreatment and poor cognition would be stronger among community controls than among people with first-episode of psychosis (FEP); compared to abuse, neglect would show stronger associations with educational attainment and cognition; the association between childhood maltreatment and IQ would be partially accounted for by ot…

Affective Disorders PsychoticIntelligence TestsSTRESSchildhood abuseBIPOLAR DISORDERASSOCIATIONschizophreniaPsychiatry and Mental healthPsychotic DisordersIQADVERSITIESCase-Control StudiesONSETRELIABILITYPHYSICAL ABUSEHumanschildhood neglectpsychosisChild AbuseVALIDITYChildRegular ArticlesTRAUMA
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Pro-inflammatory status is not a limit for longevity: case report of a Sicilian centenarian

2020

Most studies on centenarians represent them as the best model of ageing. They are defined “delayers”, if they exhibit age-related diseases between 80 and 99 years, “survivors” if they show clinically demonstrable diseases before the age of 80 years, and “escapers” when they attain their 100th year of life without any common age-associated pathologies.

Aged 80 and overGerontologySettore MED/04 - Patologia GeneraleAgingGeriatrics gerontologymedia_common.quotation_subjectLongevityLongevityBiologylanguage.human_languageCase-Control StudieslanguageHumansLimit (mathematics)Geriatrics and GerontologyCentenarianSicilianCentenarian inflammation miRNAmedia_common
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Chronic renal failure: a neglected comorbidity of COPD

2009

BACKGROUND: To the best of our knowledge, the association between COPD and chronic renal failure (CRF) has never been assessed. Lean mass is frequently reduced in COPD, and the glomerular filtration rate (GFR) might be depressed in spite of normal serum creatinine (concealed CRF). We investigated the prevalence and correlates of both concealed and overt CRF in elderly patients with COPD. METHODS: We evaluated 356 consecutive elderly outpatients with COPD enrolled in the Extrapulmonary Consequences of COPD in the Elderly Study and 290 age-matched outpatients free from COPD. The GFR was estimated using the Modification of Diet in Renal Disease Study Group equation. Patients were categorized a…

Aged 80 and overMaleComorbidityMiddle AgedSettore MED/10 - Malattie Dell'Apparato RespiratorioPulmonary Disease Chronic ObstructiveCOPD ElderlyCase-Control StudiesCreatininePrevalenceHumansKidney Failure ChronicRegression AnalysisFemaleAgedGlomerular Filtration Rate
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Compensatory strategies in processing facial emotions: evidence from prosopagnosia.

2006

We report data on the processing of facial emotion in a prosopagnosic patient (H.J.A.). H.J.A. was relatively accurate at discriminating happy from angry upright faces, but he performed at chance when the faces were inverted. Furthermore, with upright faces there was no configural interference effect on emotion judgements, when face parts expressing different emotions were aligned to express a new emergent emotion. We propose that H.J.A.'s emotion judgements relied on local rather than on configural information, and this local information was disrupted by inversion. A compensatory strategy, based on processing local face parts, can be sufficient to process at least some facial emotions.

Aged 80 and overMaleFacial expressionChi-Square DistributionCognitive NeuroscienceEmotionsInformation processingExperimental and Cognitive PsychologyRecognition PsychologyFacial recognition systemFacial ExpressionBehavioral NeuroscienceProsopagnosiaExpression (architecture)Pattern Recognition VisualFace (geometry)Case-Control StudiesReaction TimeHumansPsychologyComprehensionPhotic StimulationCognitive psychologyVisual agnosiaAgedNeuropsychologia
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