Search results for "Centro"
showing 10 items of 643 documents
The reason for a project that was never performed: Alvar Aalto and the residential complex in Pavia (1966-68)
2015
This paper aims to analyze the characteristics of the project for the residential complex "Patrizia" in Pavia by Alvar Aalto (1966-1968). Although not realized, for political and economic reasons, the project offers an interesting example of urban planning in an “organic key”. In particular, this paper aims to contextualize the project of Aalto in the broader context of the residential building in Italy after World War II, when the problems of reconstruction and "home" are the heart of the debate on architecture. The project, in fact, takes place in the years immediately following the experiments of the social housing plan INA CASA (1949-63), which - with differences in design and architect…
Evidence for a novel cytoplasmic processing event in ribosome maturation in the sea urchin Paracentrotus lividus
2010
In this work, we demonstrate the existence of a cytoplasmic processing step, never before described, involving both the pre-ribosomal subunits in the sea urchin Paracentrotus lividus. Northern-blot hybridization, primer extension, S1 mapping experiments and in situ hybridizations allowed us to demonstrate that cytoplasmic processed particles are successively re-imported into the nucleus, where maturation of their RNAs is completed prior to being exported to the cytoplasm. Our findings lead to the proposal of a new model of ribosome maturation and shuttling. Moreover, preliminary data from our laboratory suggest that the maturation pathway we propose in P. lividus may not be unique to the se…
Determination ofHER2amplification in primary breast cancer using dual-colour chromogenicin situhybridization is comparable to fluorescencein situhybr…
2010
García-Caballero T, Grabau D, Green A R, Gregory J, Schad A, Kohlwes E, Ellis I O, Watts S & Mollerup J (2010) Histopathology56, 472–480 Determination of HER2 amplification in primary breast cancer using dual-colour chromogenic in situ hybridization is comparable to fluorescence in situ hybridization: a European multicentre study involving 168 specimens Aims: Fluorescence in situ hybridization (FISH) can be used to reveal several genomic imbalances relevant to proper cancer diagnosis and to the correct treatment regime. However, FISH requires expensive and advanced fluorescence microscopes in addition to expertise in fluorescence microscopy. To determine whether a newly developed dual-colou…
Antimicrobial peptides from echinoderms as antibiofilm agents: a natural strategy to combat bacterial infections
2014
AbstractIncreased attention has been focused on marine invertebrates as a source of bioactive molecules for biomedical applications. Many bioactive molecules are part of the innate immune system. Some more recently isolated compounds, mainly from the sea urchin and the sea cucumber, are antimicrobial peptides (AMPs) active against Gram-positive and Gram-negative bacteria, and fungi. In this review we described the most recent studies on AMPs isolated from echinoderms. AMPs are small peptides (< 10 kDa) with cationic charge and amphipathic structure. Recently, it was demonstrated that in the coelomocyte lysates of Paracentrotus lividus and Holothuria tubulosa, AMPs possess activity against s…
Profesorado : revista de curriculum y formación del profesorado
2008
El artículo constituye una reflexión sobre el contexto de desmovilización actual en el que los profesionales de la educación admiten un grado de participación muy bajo en las decisiones educativas. Se plantea la investigación sobre la práctica, la investigación-acción participante como el camino para construir conocimiento crítico sobre la escuela y por lo tanto como forma y fondo del asesoramiento, la formación y el apoyo al profesorado. El artículo parte del análisis de las condiciones epistemológicas y académicas que impiden un mayor desarrollo de la investigación-acción, defendiendo que el conocimiento ha de constituir para el sujeto una herramienta de emancipación y no de sometimiento.…
[Be(ND 3 ) 4 ]Cl 2 : Synthesis, Characterisation and Space‐Group Determination Guided by Solid‐State Quantum Chemical Calculations
2013
Treatment of BeCl2 with dry liquid ND3 and subsequent removal of the solvent leads to the colourless microcrystalline powder of [Be(ND3)4]Cl2. It crystallises in the orthorhombic space group Pna21 with a = 9.395(4), b = 11.901(6), c = 6.761(3) A, V = 755.9(6) and Z = 4 at 27 °C, and a = 9.3736(8), b = 11.8162(12), c = 6.6596(6) A, V = 737.62(12) and Z = 4 at –269.6 °C. The structure contains the tetrahedral tetraammineberyllium(II) cation which follows the octet rule. It was shown to be stable under ambient conditions and temperatures up to approximately 175 °C. We additionally discuss the aid of solid-state quantum chemical calculations for the assignment of proper crystallographic space g…
Integrismo político en EEUU / 6. La versión española
2004
Crianças de dois anos de idade como coconstrutoras de cultura
2009
Comment la culture se co-construit-elle au micro-niveau des interactions quotidiennes dans un service d’accueil de la petite enfance? Quelle est cette ‘culture’ construite, qui sont les constructeurs et comment procedent-ils? L’article s’appuie sur une etude de cas portant sur les interactions entre enfants de deux ans. Pour cette etude, des enregistrements-videos ont ete effectues deux fois par mois pendant sept mois dans un service d’accueil, en Finlande. Lors de ces enregistrements, les enfants avaient des objets avec lesquels jouer. Quatre seances ont ete choisies pour l’analyse qualitative. Au cours de la premiere seance, les enfants ont produit une contre-culture aux tentatives de l’e…