Search results for "Clos"
showing 10 items of 1439 documents
A combined single range and single image device for low-cost measurement of building facade features
2008
The dimensions of building facades and window apertures are usually determined by making direct measurements using tapes and plummets. This approach, however, has a number of drawbacks including the physical risk to which the persons making the measurements are exposed. This paper proposes an indirect approach based on close range photogrammetry that is inexpensive, simple, fast and safe, and which does not require specialist staff or direct ground control measurements. The method is based on taking a picture using a digital camera and measuring the distance to the object using a handheld laser distance meter. Both items of equipment are mounted on a specially designed support that allows t…
Helical Shift Mechanics of Rubber V-Belt Variators
2011
A very common configuration of V-belt variators for motorcycles considers the correction of the belt tensioning depending on the resistant torque by means of suitable helical-shaped tracks allowing the driven half-pulleys to close/open. The theoretical model for belt-pulley coupling is rather complex for this configuration, where one half-pulley may run in advance and the other one behind with respect to the belt, and requires the repeated numerical solution of a strongly nonlinear differential system by a sort of shooting technique, until all the operating conditions are fulfilled (angular contact extent, torque, and axial force). After solving the full equations, the present study develop…
Integrated stratigraphy of the Oxfordian global stratotype section and point (GSSP) candidate in the Subalpine Basin (SE France).
2014
44 pages; International audience; An integrated biostratigraphic approach, based on ammonites, calcareous nannofossils, dinoflagellates, combined with sedimentology, carbon-isotope and physical stratigraphy, is proposed for the Subalpine Basin (Thuoux and Saint-Pierre d'Argençon sections). Within the expanded marl deposits of the Terres Noires Fm., the Callovian-Oxfordian boundary is particularly well defined by ammonite taxa from different families (i.e. Cardioceratidae, Oppeliidae, Aspidoceratidae and Perisphinctidae), calcareous nannoplankton (first occurrence of large-sized Stephanolithion bigotii) and dinoflagellate cysts (first occurrence of Wanaea fimbriata). This precise biostratigr…
Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mous…
2013
The t(8;21) chromosomal translocation activates aberrant expression of the AML1-ETO (AE) fusion protein and is commonly associated with core binding factor acute myeloid leukaemia (CBF AML). Combining a conditional mouse model that closely resembles the slow evolution and the mosaic AE expression pattern of human t(8;21) CBF AML with global transcriptome sequencing, we find that disease progression was characterized by two principal pathogenic mechanisms. Initially, AE expression modified the lineage potential of haematopoietic stem cells (HSCs), resulting in the selective expansion of the myeloid compartment at the expense of normal erythro- and lymphopoiesis. This lineage skewing was foll…
Exploring twitter for csr disclosure: influence of ceo and firm characteristics in latin american companies
2018
Social networks, which are characterised by accessibility and interactivity, offer great potential for dialogue between companies and stakeholders, for example as platforms for publishing information on aspects of corporate social responsibility (CSR). In this paper, we use a synthetic index to analyse levels of CSR disclosure via Twitter, and identify explanatory variables of this disclosure by studying the demographic characteristics of the Chief Executive Officer (CEO) and of the company. This synthetic index was based on data for 93 companies located in the four countries of the Pacific Alliance (Chile, Colombia, Mexico, and Peru), using categories based on the 2016 Global Reporting Ini…
A stereoselective synthesis of (+)-malyngolide via a ring-closing olefin metathesis
2000
Abstract A very short and stereoselective synthesis of the non-natural enantiomer of malyngolide from l -erythrulose is described. Key features of the synthesis are the Felkin–Anh diastereoselective allylation of a polyoxygenated ketone and the allylation/metathesis/allylic oxidation protocol recently described by our group.
Synthetic Approaches to Anti-Inflammatory Macrolactones of the Oxacyclododecindione Type
2015
Various synthetic approaches to the oxacyclododecindione-type macrolactones, known for their potent anti-inflammatory activity, are presented. These include an attempted carbonylative ring closure, a hydroacylation route, and an approach by ring-closing metathesis and double bond isomerization, as well as a strategy including ring-closing metathesis/unsaturation. The last route allowed the preparation of a bioactive analogue of the recently described 14-deoxyoxacyclododecindione.
Properties and interactions – melting point of tribromobenzene isomers
2021
The melting points of tribromobenzene isomers are correlated with the number, nature and distribution of intermolecular interactions in their structures.
Closed-loop recycling. A case study of films for greenhouses
2010
Abstract The degradation undergone by plastic films used for greenhouse coverage is the main cause of the worsening of the processability, of the mechanical properties and of the durability of secondary materials obtained by their recycling. This means that this secondary material cannot be processed to produce films for the same applications (closed-loop recycling). In this work different strategies are proposed to improve the processability, some mechanical properties and the resistance to photo-oxidation of these secondary materials. In particular, homopolymer blends or multilayer films where the secondary material is used in combination with virgin polymer give the best results.
0152 : Effects of connexin 43 inhibition on mitochondrial function in cardiac skinned fibers and isolated mitochondria
2015
Connexin 43 (Cx43) is a main component of intercellular gap junction channels in cardiomyocytes. The presence of Cx43 in heart mitochondria has been also reported, where it may participate in energy metabolism and protection against ischemia. Given the key role for mitochondria in pathogenesis of heart diseases, we examined how mitochondrial function could be altered in case of Cx43 pharmacological inhibition by carbenoxolone (CBX). Oxygen consumption rates under various substrate conditions were determined either in ventricles from pig hearts using saponin-permeabilized fibers, or in isolated mitochondria from rat hearts. Measurements of mitochondrial membrane potential (ΔΨ) and reactive o…