Search results for "Concentration."

showing 10 items of 1849 documents

Mild dehydration: a risk factor of urinary tract infection?

2003

Bacterial growth in the urinary tract is usually prevented by host factors including bacterial eradication by urinary and mucus flow, urothelial bactericidal activity, urinary secretory IgA, and blood group antigens in secretions which interfere with bacterial adherence. Bacterial eradication from the urinary tract is partially dependent on urine flow and voiding frequency. Therefore, it seems logical to postulate a connection between fluid intake and the risk of urinary tract infections (UTIs). However, experimental and clinical data on this subject are conflicting. Experimental studies concerning the effect of water intake on susceptibility and course of UTIs were predominantly performed …

Nutrition and DieteticsDehydrationUrinary systemDrinkingMedicine (miscellaneous)PhysiologyHost defenceHydrogen-Ion ConcentrationUrineBiologyurologic and male genital diseasesAntimicrobialMucusfemale genital diseases and pregnancy complicationsAnti-Bacterial AgentsBlood group antigensFluid intakeRisk FactorsMild dehydrationUrinary Tract InfectionsImmunologyHumansSecretory IgAEuropean Journal of Clinical Nutrition
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Saponins from the Roots of Nylandtia spinosa

2007

From the roots of Nylandtia spinosa, four new triterpene saponins, 3- O-beta- d-glucopyranosylpresenegenin 28- O-beta- d-galactopyranosyl-(1-->4)-[alpha- l-arabinopyranosyl-(1-->3)]-beta- d-xylopyranosyl-(1-->4)-[beta- d-apiofuranosyl-(1-->3)]-alpha- l-rhamnopyranosyl-(1-->2)-beta- d-fucopyranosyl ester ( 1), 3- O-beta- d-glucopyranosylpresenegenin 28- O-beta- d-galactopyranosyl-(1-->4)-[alpha- l-arabinopyranosyl-(1-->3)]-beta- d-xylopyranosyl-(1-->4)-alpha- l-rhamnopyranosyl-(1-->2)-beta- d-fucopyranosyl ester ( 2), 3- O-beta- d-glucopyranosylpresenegenin 28- O-beta- d-apiofuranosyl-(1-->4)-[beta- d-galactopyranosyl-(1-->2)]-beta- d-xylopyranosyl-(1-->4)-alpha- l-rhamnopyranosyl-(1-->2)-be…

Nylandtia spinosaCoumaric AcidsSpermidineStereochemistrySaponinPharmaceutical SciencePharmacognosyPlant RootsAnalytical ChemistryInhibitory Concentration 50TriterpeneDrug DiscoveryHumansNuclear Magnetic Resonance BiomolecularPharmacologychemistry.chemical_classificationPlants MedicinalMolecular StructureChemistryOrganic ChemistryGlycosideTenuifolinSaponinsTriterpenesTerpenoidPolygalaceaeHuman colon cancerComplementary and alternative medicineMolecular MedicineDrug Screening Assays AntitumorJournal of Natural Products
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About entangled networks of worm-like micelles: a rejected hypothesis

1996

We report new results from small-angle neutron scattering on d(1 2)-cyclohexane/lecithin/water micellar solutions performed as a function of the water content (w(o)), temperature (T) and dispersed phase volume fraction (phi). The data from dilute samples are interpretable in terms of the existence of giant cylindrical reverse micelles and are well fit with a core-shell model (that provides the micelle structure and dimensions) with values of 28 and 45 Angstrom for the inner core and the outer shell radii, almost independent on temperature and concentration. Such a result could appear consistent with the current idea that worm-like micelles are living polymers. On the contrary, the appearanc…

ORGANOGELSPolymers and PlasticsSANSChemistryInner coreForm factor (quantum field theory)Concentration effectThermodynamicsMineralogyliving polymersNeutron scatteringgelsSmall-angle neutron scatteringMicelleLIGHT-SCATTERINGCondensed Matter::Soft Condensed MatterColloid and Surface ChemistryMICROEMULSIONSMicellar solutionsMaterials Chemistryreverse micellesPhysical and Theoretical ChemistryStructure factorLECITHIN REVERSE MICELLESColloid and Polymer Science
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Antifungal Activity of Biocontrol Agents In Vitro and Potential Application to Reduce Mycotoxins (Aflatoxin B1 and Ochratoxin A)

2021

Food bio-preservatives are requested as substituents of chemical pesticides in food. The aim of this study was to carry out a screening of twenty biocontrol agents (BCAs) for their potential fungicidal activity in vitro. Twenty BCAs were tested against ten pathogenic fungi. Some of the cell-free supernatants (CFS) tested showed in vitro antifungal activity versus pathogenic fungi. The highest fungicidal activity was observed in the fermented CFS of Paenibacillus chibensis CECT 375, Bacillus amyloliquefaciens CECT 493, and Pantoea agglomerans CECT 850, which showed a minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) values of 125 and 250 g/L, respectively. The…

Ochratoxin AAflatoxinAflatoxin B1Antifungal AgentsBacillus amyloliquefaciensPaenibacillus alveiHealth Toxicology and Mutagenesisved/biology.organism_classification_rank.speciesreductionIn Vitro TechniquesToxicologyArticlePoisonsbiocontrol agentschemistry.chemical_compoundMinimum inhibitory concentrationBacillus amyloliquefaciensmycotoxinsFood sciencePest Control BiologicalMycotoxinbio-preservationCell-Free SystembiologyPantoeaved/biologyRfood and beveragesin vitrobiology.organism_classificationOchratoxinsPantoea agglomeransFungicides IndustrialchemistryMedicinePaenibacillus polymyxaPaenibacillusantifungalToxins
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Natural co-occurrence of ochratoxin A, ochratoxin B and aflatoxins in Sicilian red wines

2015

The natural occurrence of ochratoxin A, ochratoxin B, aflatoxin B1, aflatoxin B2, aflatoxin G1 and aflatoxin G2 (OTA, OTB, AFB1, AFB2, AFG1, AFG2) in red wines was investigated by HPLC/FLD after immunoaffinity column clean-up in 57 market samples produced in Sicily (Italy). The results showed a very low incidence of these mycotoxins in analysed samples, confirming the high degree of quality and safety of Sicilian red wines. The results indicated 71.9% and 64.9% positive samples for OTA and OTB respectively, with an average level of 0.13 μg l(-1), well below the European maximum permitted levels (MLs). The aflatoxin most frequently detected in the samples was AFG1, present in 57.9% of sample…

Ochratoxin AAflatoxinAflatoxin B1Health Toxicology and MutagenesisOchratoxin BFood ContaminationWineAverage levelaflatoxin G2Toxicologyaflatoxin G1Sensitivity and SpecificityFluorescencechemistry.chemical_compoundAflatoxinsimmunoaffinity columnFood scienceHPLC/FLD analysiMycotoxinSicilyChromatography High Pressure LiquidWineChromatographyPublic Health Environmental and Occupational HealthGeneral ChemistryGeneral MedicineOchratoxinsimmunoaffinity column wine aflatoxin B-2 aflatoxin G(1) ochratoxin B ochratoxin A aflatoxin B-1 aflatoxin G(2) HPLC/FLD analysischemistryaflatoxin B2Maximum Allowable Concentrationochratoxin Aochratoxin BFood Science
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An overview of ochratoxin A in beer and wine.

2007

Ochratoxin A (OTA) is a mycotoxin produced mainly by several fungal species of the genera Aspergillus and Penicillium. This mycotoxin has been shown to be nephrotoxic, hepatotoxic, teratogenic and carcinogenic to animals and has been classified as a possible carcinogen to humans. OTA occurs in a variety of foods, including beer and wine. Reports on OTA occurrence in beer indicate that this is a worldwide problem due to the widespread consumption of this beverage. At present, the European Union (EU) has not set a maximum allowable limit (MAL) for this mycotoxin in beer, although there is a limit in barley and malt. Studies carried out in different countries agree in the high proportion of sa…

Ochratoxin AFood ContaminationWineBiologyMicrobiologychemistry.chemical_compoundPenicillium verrucosumPrevalencemedia_common.cataloged_instanceFood scienceEuropean unionMycotoxinOchratoxinmedia_commonWinePenicilliumfood and beveragesBeerGeneral Medicinebiology.organism_classificationOchratoxinsAspergilluschemistryWhite WineConsumer Product SafetyPenicilliumMaximum Allowable ConcentrationFood ScienceInternational journal of food microbiology
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Direct Analysis of Psilocin and Muscimol in Urine Samples Using Single Drop Microextraction Technique In-Line with Capillary Electrophoresis

2020

The fully automated system of single drop microextraction coupled with capillary electrophoresis (SDME-CE) was developed for in-line preconcentration and determination of muscimol (MUS) and psilocin (PSC) from urine samples. Those two analytes are characteristic active metabolites of Amanita and Psilocybe mushrooms, evoking visual and auditory hallucinations. Study analytes were selectively extracted from the donor phase (urine samples, pH 4) into the organic phase (a drop of octanol layer), and re-extracted to the acidic acceptor (background electrolyte, BGE), consisting of 25 mM phosphate buffer (pH 3). The optimized conditions for the extraction procedure of a 200 &micro

OctanolAnalyteLiquid Phase MicroextractionCalibration curveAmanitacapillary electrophoresisPharmaceutical ScienceElectrolyteUrinesingle drop microextraction01 natural sciencesArticleAnalytical Chemistrylcsh:QD241-44103 medical and health scienceschemistry.chemical_compound0302 clinical medicineCapillary electrophoresislcsh:Organic chemistryLimit of DetectionDrug DiscoverymedicineHumans030216 legal & forensic medicinePhysical and Theoretical ChemistrypsilocinChromatographyChemistrygreen chemistry010401 analytical chemistryOrganic ChemistryElectrophoresis CapillaryHydrogen-Ion ConcentrationmuscimolurinePsilocybin0104 chemical sciencesDilutionChemistry (miscellaneous)PsilocinCalibrationHallucinogensSolventsMolecular MedicinePsilocybemedicine.drugMolecules
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Concentration Dynamics in the Market for Audit of Public Interest Entities in Latvia

2020

This paper studies the dynamics of concentration levels in the market for audit of public interest entities (further PIEs) in Latvia from 2016 to 2018. This is important to identify initial effects on concentration and the likely consequences of the new EU statutory audit legislation (i.e. Directive 2014/56/EU and Regulation 537/2014) entered into force in June 2016. This paper relies primarily on the analysis of the annual reports of Latvian PIE audit firms and their associates and computes some key measures describing concentration – the Herfindahl-Hirschman index and concentration ratios CR1 or CR4. It also analyses market concentration in different categories of PIEs, notably banks. The…

OligopolyIndex (economics)business.industryBig FourLegislationAccountingAuditMarket concentrationbusinessDirectivePublic interest
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Polymeric Selectin Ligands Mimicking Complex Carbohydrates: From Selectin Binders to Modifiers of Macrophage Migration

2016

Novel polymeric cell adhesion inhibitors were developed in which the selectin tetrasaccharide sialyl-LewisX (SLeX ) is multivalently presented on a biocompatible poly(2-hydroxypropyl)methacrylamide (PHPMA) backbone either alone (P1) or in combination with O-sulfated tyramine side chains (P2). For comparison, corresponding polymeric glycomimetics were prepared in which the crucial "single carbohydrate" substructures fucose, galactose, and sialic acid side chains were randomly linked to the PHPMA backbone (P3 or P4 (O-sulfated tyramine)). All polymers have an identical degree of polymerization, as they are derived from the same precursor polymer. Binding assays to selectins, to activated endo…

OligosaccharidesTyramine02 engineering and technologyLigands010402 general chemistry01 natural sciencesCatalysisFucoseInhibitory Concentration 50chemistry.chemical_compoundPolymethacrylic AcidsCell MovementHuman Umbilical Vein Endothelial CellsSide chainHumansTetrasaccharideMethacrylamideSialyl Lewis X AntigenCell adhesionCells CulturedMacrophagesGeneral ChemistrySurface Plasmon ResonanceFlow Cytometry021001 nanoscience & nanotechnologyIn vitro0104 chemical sciencesSialic acidMicroscopy Fluorescence MultiphotonNanomedicinechemistryBiochemistrySelectins0210 nano-technologySelectinAngewandte Chemie International Edition
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Clinical correlates of change in inflammatory biomarkers: The Framingham Heart Study

2013

Objectives: Traditional clinical risk factors are associated with inflammation cross-sectionally, but associations of longitudinal variation in inflammatory biomarkers with corresponding changes in clinical risk factors are incompletely described. We sought to analyze clinical factors associated with change in inflammation in the community.Methods: We studied 3013 Framingham Offspring (n = 2735) and Omni Cohort (n = 278) participants (mean age 59 years, 55% women, 9% ethnic/racial minority) who attended two consecutive examination cycles (mean 6.7 years apart). We selected ten inflammatory biomarkers representing distinctive biological functions: C-reactive protein (CRP), intercellular adhe…

OncologyMaleBLOOD-PRESSUREIsoprostanesFramingham Heart StudyRisk FactorsMyocardial infarctionOXIDATIVE STRESSskin and connective tissue diseasesChemokine CCL2Biological markersbiologyLongitudinal studiesMiddle AgedIntercellular Adhesion Molecule-1Inflammatory biomarkersC-REACTIVE PROTEINP-SelectinADIPOSE-TISSUEMassachusettsCardiovascular DiseasesCARDIOVASCULAR-DISEASEFemalemedicine.symptomCardiology and Cardiovascular MedicineVasculitisVasculitismedicine.medical_specialtyInflammationArticleInternal medicinemedicineHumansReceptors Tumor Necrosis Factor Type IIInterleukin 6AgedInflammationbusiness.industryInterleukin-6PERIPHERAL ARTERIAL-DISEASEC-reactive proteinOsteoprotegerinADHESION MOLECULE-1medicine.diseasePHOSPHOLIPASE A(2)Blood pressurePLASMA-CONCENTRATIONMYOCARDIAL-INFARCTIONImmunology1-Alkyl-2-acetylglycerophosphocholine Esterasebiology.proteinsense organsbusinessBiomarkers
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