Search results for "Critical"
showing 10 items of 3024 documents
Comparative Analysis of Mega Road Construction Projects in Term of Innovation
2020
Purpose This paper examines, using critical realism, the causes and mechanisms of innovation in three civil road construction projects. Its focus is to examine how value can be created within the design process through innovation. Emphasis is placed on Best Value Procurement (BVP) as a procurement strategy where the preferred contractor is considered the expert, as it is the first case of its use in Norwegian road construction projects. Data was collected through surveys and interviews. Findings indicate that procurement using early involvement is innovative in the design process yet must be adapted, to allow for early planning of innovative ideas that help, to foster innovative solutions. …
El reto de la internacionalización para las Pequeñas y Medianas Empresas españolas
2017
While many studies have widely worked out on finding out the different relationships underlying the birth and prompt development of Small and Medium Enterprises (SMEs), we argue that getting an in depth approach to the problematic scene that takes place once they are keen on having a successful internationalization plan may have been understudied. Therefore, the aim of this research is that of identifying critical challenges faced by Spanish SMEs during an internationalization process. We do so by taking a qualitative approach. The current research contributes to the literature by adding new and renewed perspectives to the field, thanks to the qualitative analysis carried out through four i…
Parents' experiences of neonatal transfer. A meta-study of qualitative research 2000-2017.
2018
Transfers of critically ill neonates are frequent phenomena. Even though parents’ participation is regarded as crucial in neonatal care, a transfer often means that parents and neonates are separated. A systematic review of the parents’ experiences of neonatal transfer is lacking. This paper describes a meta-study addressing qualitative research about parents’ experiences of neonatal transfer. Through deconstruction and reflections of theories, methods and empirical data, the aim was to achieve a deeper understanding of theoretical, empirical, contextual, historical and methodological issues of qualitative studies concerning parents’ experiences of neonatal transfer over the course of this …
Introduction and Empirical Framework
2021
Part III describes the methodology used to converge the micro and macro approach. The methodology chosen has been the case study. The first part of this chapter justifies the election of the methodology. The second part is the explanation of the case study. Through diverse sources of archival data as well as scientific papers and an interview with her founder (Dr. Mateo), the chapter addresses the issue of social entrepreneurship’s role as a problem solver showing the case of a social entrepreneur and the technology developed to change the context. The methodology is presented as a time series that the entrepreneur follows until she finds a way to add value to society. The critical moment a…
Life Experience, Values and Education
2016
The paper deals with the contemporary problems of education – its functions, mission, humanistic essence and need for the understanding of value. Education is not only school training or getting competences at the highest educational institutions. It is understood as a life experience, where cognition, judgement and practical activity come together in one complex. Nowadays the most popular systems of education are structured on the model based mainly on pragmatism, professionalism, information, technology, to which philosophers are trying to attach moral and cultural dimensions, but their views do not carry much weight. The author agrees with R. Dahrendorf that we need empathetic education …
Nonlinear elliptic equations with asymmetric asymptotic behavior at $pminfty$
2016
We consider a nonlinear, nonhomogeneous Dirichlet problem with reaction which is asymptotically superlinear at $+infty$ and sublinear at $-infty$. Using minimax methods together with suitable truncation techniques and Morse theory, we show that the problem has at least three nontrivial solutions one of which is negative.
Staphylococcus aureus alpha toxin mediates polymorphonuclear leukocyte-induced vasocontraction and endothelial dysfunction.
2002
The effect of Staphylococcus aureus alpha toxin (alpha-toxin) on selectin-mediated neutrophil adhesion was investigated in polymorphonuclear leukocyte- (PMN) induced vasocontraction and endothelial dysfunction. Adherence of human PMNs to rat aortic endothelium increased significantly following stimulation of the endothelium with alpha-toxin (0.1, 0.5, and 1 microg/mL). This effect could be significantly attenuated by monoclonal antibodies directed against P-selectin or fucoidin, a carbohydrate known to block selectins. Unstimulated human PMNs (10(6)cells/mL) were added to organ chambers containing rat aortic rings stimulated with alpha-toxin (0.5 microg/mL). PMNs elicited a significant vaso…
Vasopressor-Sparing Strategies in Patients with Shock: A Scoping-Review and an Evidence-Based Strategy Proposition
2021
Despite the abundant literature on vasopressor therapy, few studies have focused on vasopressor-sparing strategies in patients with shock. We performed a scoping-review of the published studies evaluating vasopressor-sparing strategies by analyzing the results from randomized controlled trials conducted in patients with shock, with a focus on vasopressor doses and/or duration reduction. We analyzed 143 studies, mainly performed in septic shock. Our analysis demonstrated that several pharmacological and non-pharmacological strategies are associated with a decrease in the duration of vasopressor therapy. These strategies are as follows: implementing a weaning strategy, vasopressin use, system…
Mechanical ventilation in patients with cardiogenic pulmonary edema: a sub-analysis of the LUNG SAFE study
2022
Supported by Centro de Investigación Biomédica en Red (CIBER)‑Enfermedades respiratorias, Madrid, Spain (CB17/06/00021) and Fundación para el Fomento en Asturias de la Investigación Científica aplicada y la tecnología (FICYT, AYUD2021/52014). RRG is the recipient of a grant from Instituto de Salud Carlos III, Madrid, Spain (CM20/00083).
The discursive legitimation strategies of a nascent market
2017
Since the introduction of Gold&Green Foods Ltd’s Pulled Oats (Nyhtökaura) to the Finnish market in the spring 2016, the Finnish media has been increasingly reviewing different plant-based protein products. Gold&Green Ltd’s Pulled Oats has experienced extensive media coverage amongst other Finnish plant-based protein products which have been launched during 2016 such as VersoFood Ltd’s Härkis, Viipurilainen Kotileipomo’s Puhtikaura etc. It has yet to be seen whether the sudden inception of several plant-based protein product innovations will be defined as a pivotal era in the Finnish food industry or just a passing trend. Finnish media has aldo categorized MiFu as one of the up and coming fo…