Search results for "Cyclooctadiene"

showing 9 items of 9 documents

Synthesis of a Tetraazido-Substituted 2-Tetrazene from 1,5-Cyclooctadiene and Iodine Azide

1997

In contrast to the addition of iodine azide to cyclooctene (1) or 1,3-cyclooctadiene (5), its reaction with 1,5-cyclooctadiene (12) leads mainly to the surprisingly stable tetraazido-substituted 2-tetrazene 14 The structure of this was established by 15N-NMR studies and an X-ray structural analysis. Treatment of 14 with hydrochloric acid yields the diazido-substituted 9-azabicyclo[3.3.1]nonane 20.

15-CyclooctadieneOrganic Chemistrychemistry.chemical_elementHydrochloric acidGeneral ChemistryIodineMedicinal chemistrychemistry.chemical_compoundchemistryCycloocteneTetrazeneOrganic chemistryAzidePhysical and Theoretical ChemistryNonaneLiebigs Annalen
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Selective homogeneous hydrogenation of cycloocta-1,5, and cycloocta-1,3-diene to cyclooctene in the presence of (η4-cycloocta-1,5-diene)(η6-cycloocta…

1983

Cyclooctadiene isomers (1,3- and 1,5-COD) are selectively, homogenously hydrogenated to cyclooctene (C8H14) in tetrahydrofuran (THF) solution, under mild conditions of temperature (20 °C) and hydrogen pressure (1 atm), in the presence of catalytic amounts of (cycloocta-1,5-diene)(cycloocta-1,3,5,-triene)ruthenium(0), [Ru(η4-COD)(η6-C8H10)] (1). The rate of hydrogenation is higher when 1,3-COD is the substrate. Evidence for the isomerization 1,5-COD → 1,3-COD is reported. Similar studies carried out in several alcoholic solutions, although showing a decreased selectivity in the hydrogenation, confirm the isomerization 1,5-COD → 1,3-COD, and allow a discrimination between the isomerization an…

DieneNorbornadienechemistry.chemical_elementNoyori asymmetric hydrogenationPhotochemistryMedicinal chemistryCatalysisRutheniumInorganic Chemistrychemistry.chemical_compoundchemistryCycloocteneMaterials ChemistryPhysical and Theoretical ChemistryIsomerizationCyclooctadieneInorganica Chimica Acta
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Classics Meet Classics: Theoretical and Experimental Studies of Halogen Bonding in Adducts of Platinum(II) 1,5-Cyclooctadiene Halide Complexes with D…

2021

Complexes of PtX2COD (X = Cl, Br, I; COD = 1,5-cyclooctadiene) were cocrystallized with classical halogen-bond donors (CHI3, I2, and 1,4-diiodotetrafluorobenzene (FIB)), resulting in noncovalently ...

Halogen bond010405 organic chemistry15-CyclooctadieneHalidechemistry.chemical_elementGeneral Chemistry010402 general chemistryCondensed Matter PhysicsIodoform01 natural sciences3. Good health0104 chemical sciencesAdductchemistry.chemical_compoundchemistryPolymer chemistryGeneral Materials SciencePlatinumCrystal Growth & Design
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CCDC 241029: Experimental Crystal Structure Determination

2004

Related Article: R.Nunez, O.Tutusaus, F.Teixidor, C.Vinas, R.Sillanpaa, R.Kivekas|2004|Organometallics|23|2273|doi:10.1021/om030635h

Space GroupCrystallographyCrystal System3-(eta^4^-15-Cyclooctadiene)-8-(dimethylthio)-closo-3-rhoda-12-dicarbadodecaborane(10)Crystal StructureCell ParametersExperimental 3D Coordinates
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Five-coordinate complexes of palladium(ii) and platinum(ii) with α-diimine and 1,5-cyclooctadiene ligands

2001

The five-coordinate complexes [PtMe(cod)(N–N′)]BF4 [cod = η2,η2-cyclooctadiene, N–N′ = (6-R2)C5H3N-2-CHNR1 (R1 = C6H4OMe-4, R2 = H (1), Me (2); R1 = CMe3, R2 = H (3), Me (4); R1 = (R)-bornyl, R2 = Me (5))] are readily obtained from the reaction of [PtClMe(cod)] with N–N′ in the presence of NaBF4. The preparation of [PtMe(cod)(6)]BF4 (6 = 4-MeOC6H4NCHCHNC6H4OMe-4), [PdMe(cod)(N–N′)]BF4 and [PtCl(cod)(N–N′)]BF4 (N–N′ = 2, 4) requires chloride abstraction by AgBF4 from [PtClMe(cod)], [PdClMe(cod)] and [PtCl2(cod)], respectively, followed by coordination of N–N′. The NMR spectral data suggest a trigonal-bipyramidal structure with chelating cod and N–N′ ligands, where the α-diimine and one CC bo…

StereochemistryLigandTrans effect15-Cyclooctadienechemistry.chemical_elementGeneral ChemistrySettore CHIM/08 - Chimica FarmaceuticaMedicinal chemistrychemistry.chemical_compoundchemistryMoleculeChelationPlatinumDiiminePalladiumJournal of the Chemical Society, Dalton Transactions
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Cytotoxicity and NMR Studies of Platinum Complexes with Cyclooctadiene Ligands

2014

The synthesis of a series of platinum complexes containing cyclooctadiene ligands with the general structure PtMeL(R-cod) (where L = Cl, I, nC3F7, iC3F7, nC8F17, Me, aryl, alkynyl and R = H, Me, Et, iPr, nBu, iBu, nHex, Ph) is presented. All complexes are remarkably stable and were obtained in excellent yields. Their structure in both solution and the solid state were explored by crystal structures and multinuclear (1H, 13C, 19F, 195Pt) NMR spectroscopy. Cytotoxicity experiments with selected complexes in HeLa cells revealed higher toxicity in comparison to that of cisplatin for most of the structures.

Stereochemistrychemistry.chemical_elementCrystal structure010402 general chemistry01 natural sciencesMedicinal chemistryInorganic ChemistryHeLachemistry.chemical_compoundmedicinePhysical and Theoretical ChemistryCytotoxicityta116Cisplatinbiology010405 organic chemistryArylOrganic ChemistryNuclear magnetic resonance spectroscopybiology.organism_classification3. Good health0104 chemical scienceschemistryPlatinumCyclooctadienemedicine.drugOrganometallics
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Reactions of α-diimino ligands with the chloro-bridged dimer [RhCl(COD)]2(COD=1,5-cyclooctadiene)

1988

Abstract The reactions of α-diimino ligands N - N ′ [ N - N ′= 2,2′-bipyridine (bipy), C 5 H 4 N2CHNR (R= C 6 H 4 OMe- p , PyCa), RNCHCHNR (R=C 6 H 4 - OMe- p , DAB)] with [RhCl(COD)] 2 give rise to stoichiometry, solvent, ligand, and temperature dependent equilibria. In general, the 1/1 ligand/dimer reaction yields the ionic product [Rh(COD)( N - N ′)] [RhCl 2 (COD)], at room temperature. For N - N ′=DAB, the ionic form is in equilibrium with the binuclear compound [{RhCl(COD)} (μ-DAB){RhCl(COD)}] (containing a σ σ,'- N , N ′ bridging α-diimine), which becomes the predominant species at low temperatures. In [Rh(COD)( N - N ′)] [RhCl 2 (COD)], a fast exchange of the Rh(COD) unit betwe…

chemistry.chemical_classificationAldimineReaction mechanismDenticityStereochemistryLigandDimer15-CyclooctadieneCationic polymerizationMedicinal chemistryInorganic Chemistrychemistry.chemical_compoundchemistryMaterials ChemistryPhysical and Theoretical ChemistryIsomerizationInorganica Chimica Acta
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A study on the aminomercuration-nucleophilic demercuration of --1,5-cyclooctadiene; stereoselective synthesis of 2,6-disubstituted-9-aza bicyclo[3.3.…

1992

Abstract The aminomercuration of cis - cis -1,5-Cyclooctadiene with a series of mercury(II) salts followed by nucleophilic displacement of mercury by aromatic amines, water and nitrate ion has been studied. As a result, bicyclic triamines, aminoalcohols and nitrate esters have been obtained respectively in clean processes which occur under total stereoelectronic control by involvement of a tricyclic aziridium ion to afford a single stereoisomer in each case. The influence of the counter ion and the basicity of the amine on the tandem aminomercuration-demercuration is discussed.

chemistry.chemical_classificationReaction mechanismBicyclic molecule15-CyclooctadieneOrganic ChemistryBiochemistrychemistry.chemical_compoundchemistryNucleophileDrug DiscoveryOrganic chemistryAmine gas treatingStereoselectivityCounterionAminationTetrahedron
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ChemInform Abstract: Synthesis of a Tetraazido-Substituted 2-Tetrazene from 1,5- Cyclooctadiene and Iodine Azide.

2010

In contrast to the addition of iodine azide to cyclooctene (1) or 1,3-cyclooctadiene (5), its reaction with 1,5-cyclooctadiene (12) leads mainly to the surprisingly stable tetraazido-substituted 2-tetrazene 14 The structure of this was established by 15N-NMR studies and an X-ray structural analysis. Treatment of 14 with hydrochloric acid yields the diazido-substituted 9-azabicyclo[3.3.1]nonane 20.

chemistry.chemical_compoundchemistryCycloocteneTetrazene15-Cyclooctadienechemistry.chemical_elementHydrochloric acidGeneral MedicineAzideNonaneIodineMedicinal chemistryChemInform
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