Search results for "Deme"
showing 10 items of 883 documents
Synthesis of pillar[7]arene
2012
Abstract The first synthesis of pillar[7]arene is reported with two methods. Method A: the FeCl 3 -catalyzed condensation reaction of 1,4-dimethoxybenzene ( 1 ) with paraformaldehyde in CHCl 3 gave dimethoxypillar[7]arene ( 3 ). Method B: the p -toluenesulfonic acid catalyzed condensation reaction of 2,5-bis(benzyloxymethyl)-1,4-dimethoxybenzene ( 2 ) in CH 2 Cl 2 gave compound 3 . Demethylation of 3 with BBr 3 gave pillar[7]arene ( 4 ). The pillar[7]arene might be a perspective macrocyclic host in host–guest chemistry.
Voluntary Imitation in Alzheimer’s Disease Patients
2016
International audience; Although Alzheimer's disease (AD) primarily manifests as cognitive deficits, the implicit sensorimotor processes that underlie social interactions, such as automatic imitation, seem to be preserved in mild and moderate stages of the disease, as is the ability to communicate with other persons. Nevertheless, when AD patients face more challenging tasks, which do not rely on automatic processes but on explicit voluntary mechanisms and require the patient to pay attention to external events, the cognitive deficits resulting from the disease might negatively affect patients' behavior. The aim of the present study was to investigate whether voluntary motor imitation, i.e.…
Twin studies on the association of physical activity with cognitive and cerebral outcomes
2020
Regular physical activity (PA) offers positive effects on the human body. However, the effects of PA on cognition and in the brain are less clear. In this paper, we narratively review the relationship of PA with cognition and dementia, first from general perspective and then through genetically informed studies on the topic. Then we move on to imaging studies on exercise and brain anatomy first by presenting an overall picture of the topic and then discussing brain imaging studies addressing PA and brain structure in twins in more detailed way. Regarding PA and cognition or dementia, genetically informed studies are uncommon, even though the relationship between PA and cognitive ageing has …
Physical activity and exercise in mild cognitive impairment and dementia::an umbrella review of intervention and observational studies
2020
Objectives:\ud \ud The aim of this umbrella review was to determine the effect of physical activity/exercise on improving cognitive and noncognitive outcomes in people with MCI (mild cognitive impairment) and dementia.\ud \ud Design:\ud \ud Umbrella review of systematic reviews (SR), with or without meta-analyses (MAs), of randomized controlled trials (RCTs) and observational studies.\ud \ud Settings and Participants:\ud \ud People with MCI or dementia, confirmed through validated assessment measures. Any form of physical activity/exercise was included. As controls, we included participants not following any prespecified physical activity/exercise intervention or following the same standard…
Characteristics of Bipolar Patients with Cognitive Impairment of Suspected Neurodegenerative Origin: A Multicenter Cohort
2021
Bipolar disorder is associated with an increased risk of dementia with aging. Little is known regarding this association, limiting appropriate diagnosis and management. We aimed to describe the characteristics of bipolar patients with late cognitive impairment for whom the hypothesis of an underlying neurodegenerative disease had been raised. We performed a retrospective multicenter study, recruiting bipolar patients over 50 years old from five French tertiary memory centers who had undergone cerebrospinal fluid (CSF) biomarker assessment for Alzheimer’s disease (AD). Clinical, neuropsychological, and paraclinical characteristics were analyzed and 78 patients were included. The mean age at …
Clubs de convergence et effets de débordements géographiques : une analyse spatiale sur données régionales européennes, 1980-1995
2007
Our article offers an econometric model of spatial interactions for the empirical analysis of growth in European regions over the period 1980-1995. The model detects spatial spillover effects and makes it possible to take account of the European economy’s strong polarization. More specifically, by factoring in both spatial autocorrelation and spatial heterogeneity, we characterize the economic polarization pattern in European regions, identify convergence clubs, and model them as spatial regimes. We estimate a two-regime model with spatially autocorrelated errors and show that the convergence process differs between the two regimes. We find a strongly significant spatial spillover effect : …
Estimation des effets de proximité dans le processus de convergence régionale : une approche par l'économétrie spatiale sur 92 régions européennes (1…
2002
L'objectif de cet article est d'examiner les conséquences de la dépendance spatiale sur la croissance régionale et le processus de convergence. Sur un échantillon de 92 régions européennes sur la période 1980-1995, nous montrons que le modèle de b-convergence absolue doit être re-spécifié en raison de la présence d'auto-corrélation spatiale. Les méthodes de l'économétrie spatiale nous orientent vers une spécification avec erreurs spatialement auto-corrélées qui nous permet de mettre en évidence un effet de débordement géographique. Nous montrons ainsi que le taux de croissance d'une région est influencé positivement par les taux de croissance des régions contiguës.
Dioniso a Capodarso ? Ricostruzione di una statua fittile di divinità seduta in trono
2013
The analysis and reinterpretation of three coroplastic fragments found in the 1960s at the Capodarso site (in the province of Enna) allow us to attribute them to a single artefact and, in particular, to a life-size statue seated on a throne, probably a cult statue.
Lien entre démarrage de la saison des pluies et rendements agricoles observés/simulés du mil sur le site AMMA-CATCH.
2011
International audience
Kognitīvo funkciju izpēte pacientiem pēc 60 gadu vecuma ģimenes ārsta praksē
2021
Ievads. Kognitīvie traucējumi var būtiski ietekmēt indivīda darba spējas, sociālo aktivitāti un samazināt dzīves kvalitāti. Darba autore vēlas pievērst cilvēku uzmanību viegliem kognitīviem traucējumiem, jo tie var būt pirmsdemences stāvoklis. Mērķis. Agrīni atklāt iespējamus kognitīvos traucējumus pacientiem pēc 60 gadu vecuma. Materiāli un metodes. Prospektīva tipa pētījums, kas norisinājās ģimenes ārsta praksē (AS “VCA” poliklīnikā “Jugla”). Pētījumā tika iekļauti pacienti vecumā virs 60 gadiem, kuriem iepriekš nebija diagnosticēti kognitīvie traucējumi. Katrs pētījuma dalībnieks aizpildīja protokolu, kas sastāvēja no divām daļām. Pirmā daļa bija anketa, savukārt otrā – MoCA tests. Pētīj…