Search results for "Diffusion"

Widespread white matter microstructural abnormalities in bipolar disorder: evidence from mega- and meta-analyses across 3033 individuals

2019

Fronto-limbic white matter (WM) abnormalities are assumed to lie at the heart of the pathophysiology of bipolar disorder (BD);\ud however, diffusion tensor imaging (DTI) studies have reported heterogeneous results and it is not clear how the clinical\ud heterogeneity is related to the observed differences. This study aimed to identify WM abnormalities that differentiate patients with\ud BD from healthy controls (HC) in the largest DTI dataset of patients with BD to date, collected via the ENIGMA network. We gathered\ud individual tensor-derived regional metrics from 26 cohorts leading to a sample size of N = 3033 (1482 BD and 1551 HC). Mean\ud fractional anisotropy (FA) from 43 regions of i…

In vitro susceptibility of e.faecalis and c.albicans isolates from apical periodontitis to common antimicrobial agents, antibiotics and antifungal me…

2012

The aim of this study was to evaluate in vitro antimicrobial activity of 4 antibiotic agents (for E.faecalis) and 4 antifungal agents (for C.albicans) by agar dilution method. Additionally, modified strip diffusion method was used for detection of in vitro antimicrobial activities of 5% NaOCl, 2.5% NaOCl, 17% EDTA and 2% CHX and agar diffusion method for detection of in vitro susceptibilities of three intracanal medicaments for 18 E.faecalis and 18 C.albicans isolates from primary and secondary root canal infection. Isolates were recovered from 231 endodontic samples of patients, with the need of root canal treatment and retreatment. All tested E.faecalis isolates showed resistance to antib…

Evaluation of Galantamine transbuccal absorption by reconstituted human oral epithelium and porcine tissue as buccal mucosa models: Part I

2008

Over the last decade, interest in delivering drugs through buccal mucosa has increased. As a major limitation in buccal drug delivery could be the low permeability of the epithelium, the aim of this study was to evaluate the aptitude of galantamine, useful in Alzheimer's disease, to penetrate the buccal mucosa. The evaluation of the ability of galantamine to permeate through the buccal epithelium was investigated using two permeation models. Firstly, in vitro permeation experiments were carried out using reconstituted human oral non-keratinised epithelium and Transwell diffusion cells system. Results were validated by ex vivo experiments using porcine buccal mucosa as membrane and Franz typ…

2019

Objective: Severe malnutrition in patients with anorexia nervosa (AN) as well as possible trait-related aberrations lead to pronounced structural brain changes whose reversibility after recovery is currently unclear. Previous diffusion tensor imaging (DTI) studies investigating white matter (WM) microstructure alterations in AN are inconsistent. Methods: In this so far largest DTI study in adults, we investigated 33 AN patients, 20 recovered (REC), and 33 healthy women. DTI data were processed using the "DTI and Fiber tools," and the Computational Anatomy Toolbox. WM integrity, both in terms of fractional anisotropy (FA) and mean diffusivity (MD), was assessed. Results: We found a significa…

Stationary, Oscillatory, Spatio-Temporal Patterns and Existence of Global Solutions in Reaction-Diffusion Models of Three Species

2023

The goal of my Ph.D. research is to analyze three species models in order to describe the behavior of an ecological community. In particular, two reaction-diffusion systems describing different local interactions between three species have been considered to obtain species coexistence, diversity, and distribution patterns. The first analyzed model describes intraguild predation: there are an IG-predator species, an IG-prey species, and a common resource species, which is shared by both of them. The IGP interaction is of Lotka-Volterra type, coupled with nonlinear diffusion, since we assume that the IG-prey moves towards lower density areas of the IG-predator. In this model, the extinction o…

Pattern formation and bifurcation analysis for some chemotaxis-reaction-diffusion systems

Pattern formation driven by cross–diffusion in a 2D domain

2012

Abstract In this work we investigate the process of pattern formation in a two dimensional domain for a reaction–diffusion system with nonlinear diffusion terms and the competitive Lotka–Volterra kinetics. The linear stability analysis shows that cross-diffusion, through Turing bifurcation, is the key mechanism for the formation of spatial patterns. We show that the bifurcation can be regular, degenerate non-resonant and resonant. We use multiple scales expansions to derive the amplitude equations appropriate for each case and show that the system supports patterns like rolls, squares, mixed-mode patterns, supersquares, and hexagonal patterns.

Water-Dependent Blending of Pectin Films: The Mechanics of Conjoined Biopolymers

2020

Biodegradable pectin polymers have been recommended for a variety of biomedical applications, ranging from the delivery of oral drugs to the repair of injured visceral organs. A promising approach to regulate pectin biostability is the blending of pectin films. To investigate the development of conjoined films, we examined the physical properties of high-methoxyl pectin polymer-polymer (homopolymer) interactions at the adhesive interface. Pectin polymers were tested in glass phase (10&ndash

58. White matter abnormalities in attention-deficit/hyperactivity disorder: A diffusion tensor imaging study in adult patients

2009

A SUBCRITICAL BIFURCATION FOR A NONLINEAR REACTION–DIFFUSION SYSTEM

2010

In this paper the mechanism of pattern formation for a reaction-diffusion system with nonlinear diffusion terms is investigated. Through a linear stability analysis we show that the cross-diffusion term allows the pattern formation. To predict the form and the amplitude of the pattern we perform a weakly nonlinear analysis. In the supercritical case the Stuart-Landau equation is found, which rules the evolution of the amplitude of the most unstable mode. With the increasing distance from the bifurcation value of the cross-diffusion parameter, the weakly nonlinear analysis fails and a Fourier–Galerkin approach is adopted. In the subcritical case the weakly nonlinear analysis must be pushed u…