Search results for "Diss"

showing 10 items of 2500 documents

Biases in study design, implementation, and data analysis that distort the appraisal of clinical benefit and ESMO-Magnitude of Clinical Benefit Scale…

2021

BACKGROUND: The European Society for Medical Oncology-Magnitude of Clinical Benefit Scale (ESMO-MCBS) is a validated, widely used tool developed to score the clinical benefit from cancer medicines reported in clinical trials. ESMO-MCBS scores assume valid research methodologies and quality trial implementation. Studies incorporating flawed design, implementation, or data analysis may generate outcomes that exaggerate true benefit and are not generalisable. Failure to either indicate or penalise studies with bias undermines the intention and diminishes the integrity of ESMO-MCBS scores. This review aimed to evaluate the adequacy of the ESMO-MCBS to address bias generated by flawed design, im…

Data Analysis:técnicas de investigación::métodos::diseño de la investigación [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS]Cancer Researchbiasmedia_common.quotation_subjectclinical trial reportingESMO-MCBS:Otros calificadores::Otros calificadores::/farmacoterapia [Otros calificadores]ReviewMedical Oncologyclinical trial implementation:Other subheadings::Other subheadings::/drug therapy [Other subheadings]:neoplasias [ENFERMEDADES]:profesiones sanitarias::medicina::medicina interna::oncología médica [DISCIPLINAS Y OCUPACIONES]Neoplasmsclinical trial analysis:Investigative Techniques::Methods::Research Design [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT]Agency (sociology)HumansQuality (business):Health Occupations::Medicine::Internal Medicine::Medical Oncology [DISCIPLINES AND OCCUPATIONS]health care economics and organizationsmedia_commonActuarial scienceManchester Cancer Research CentreCàncer - TractamentResearchInstitutes_Networks_Beacons/mcrcClinical study designHealth technologyGénéralitésPublication biasclinical trial designAssaigs clínics - Disseny:Neoplasms [DISEASES]Clinical trialCritical appraisalOncologyResearch DesignScale (social sciences)PsychologyESMO Open
researchProduct

Ac field dependence of the susceptibility of Bi2Sr2CaCu2O8 thin films at low dc fields

1996

We have measured the ac field dependence of the ac susceptibility of 400 nm thick Bi2212 thin films at low dc fields 0 ≤μ0Ha ≤ 1 mT in transverse geometry. We show that at reduced temperaturest≤0.85 the ac field dependence can be described by the non-linear Bean model after Brandt as in Y123 thin films. Att>0.85, however, we observe a decrease of the energy dissipation and shielding capability. The critical current density at zero dc field is given byjc−4×1010(1−(T/Tc))2.8±0.1 A/m2.

Dc fieldPhysicsTransverse planeNuclear magnetic resonanceCondensed matter physicsAc fieldElectromagnetic shieldingGeneral Physics and AstronomyCritical currentDissipationThin filmCzechoslovak Journal of Physics
researchProduct

Subsurface nitrate reduction under wetlands takes place in narrow superficial zones

2017

This study aims to investigate the depth distribution of the Nitrate Reduction Potential (NRP) on a natural and a re-established wetland. The obtained NRP provides a valuable data of the driving factors affecting denitrification, the Dissimilatory Nitrate Reduction to Ammonium (DNRA) process and the performance of a re-established wetland. Intact soil cores were collected and divided in slices for the determination of Organic Matter (OM) through Loss of Ignition (LOI) as well as Dissolved Organic Carbon (DOC) and NRP spiking nitrate in batch tests. The Nitrate Reduction (NR) was fitted as a pseudo-first order rate constant (k) from where NRPs were obtained. NR took place in a narrow superfi…

Denitrification010504 meteorology & atmospheric sciencesWetland010501 environmental sciences01 natural sciencesSoilchemistry.chemical_compound:Enginyeria química [Àrees temàtiques de la UPC]NitrateDissolved organic carbonEnvironmental ChemistryOrganic matterWaste Management and Disposal0105 earth and related environmental sciencesWater Science and Technologyorganic matterchemistry.chemical_classificationgeographyNitratesgeography.geographical_feature_categoryDissimilatory nitrate reduction to ammoniumEnvironmental engineeringvertical distributionGeneral Medicinenitrate reductionAiguamollsSoil corechemistryEnvironmental chemistryWetlandsDenitrificationNitrogen Oxides
researchProduct

Dissipation of vibronic energy in a dimer

1992

Abstract The density matrix theory is used for the study of the dissipative quantum dynamics of electron transfer in a dimer. The vibrational modes of the dimer are divided into a single interaction coordinate coupling to the transfered electron and the remaining modes which form a dissipative environment. To correlate the dissipative dynamics with the exact eigenlevels computed for the model system without dissipative environment we analyse the time dependence of the expectation value of the number of vibrational quanta. We analyse the renormalisation of the eigenvalues due to the damping and the relaxation of an excitation into these states.

Density matrixChemistryQuantum dynamicsBiophysicsGeneral ChemistryElectronExpectation valueDissipationCondensed Matter PhysicsBiochemistryAtomic and Molecular Physics and OpticsElectron transferQuantum mechanicsDissipative systemRelaxation (physics)Journal of Luminescence
researchProduct

Electron-transfer dynamics in a donor—acceptor complex

1991

Abstract Density matrix theory is used for the study of the dissipative quantum dynamics of electron transfer in a donor—acceptor complex. The vibrational modes of the complex are divided into a single interaction coordinate coupling to the transferred electron and the remaining modes which form a dissipative environment. With increase of the coupling of the interaction coordinate to the environment and, thus, of the corresponding damping rate of the vibrational quanta, the results of the numerical calculations display a change from the coherent to the incoherent transfer regime. In contrast to the case of small values of the damping, the transfer dynamics become independent of the number o…

Density matrixCouplingElectron transferComputational chemistryPhononChemistryExcited stateQuantum dynamicsDissipative systemGeneral Physics and AstronomyElectronPhysical and Theoretical ChemistryMolecular physicsChemical Physics Letters
researchProduct

Witnessing non-Markovian effects of quantum processes through Hilbert-Schmidt speed

2020

Non-Markovian effects can speed up the dynamics of quantum systems while the limits of the evolution time can be derived by quantifiers of quantum statistical speed. We introduce a witness for characterizing the non-Markovianity of quantum evolutions through the Hilbert-Schmidt speed (HSS), which is a special type of quantum statistical speed. This witness has the advantage of not requiring diagonalization of evolved density matrix. Its sensitivity is investigated by considering several paradigmatic instances of open quantum systems, such as one qubit subject to phase-covariant noise and Pauli channel, two independent qubits locally interacting with leaky cavities, V-type and $\Lambda $-typ…

Density matrixPhysicsQuantum PhysicsHIlbert-Schmidt speedFOS: Physical sciencesType (model theory)non-Markovianity01 natural sciencesNoise (electronics)Settore FIS/03 - Fisica Della Materia010305 fluids & plasmassymbols.namesakePauli exclusion principleOpen quantum systemQubitQuantum mechanics0103 physical sciencessymbolsDissipative systemQuditQubitSensitivity (control systems)Quantum Physics (quant-ph)010306 general physicsQuantumPhysical Review A
researchProduct

Ligand dynamics of tert-butyl isocyanide oxido complexes of molybdenum(IV).

2014

The six-coordinate molybdenum(IV) oxido isocyanide complex 1 [Δ,Λ-OC-6-2-3-[MoO(N(p)∩N(i))2(CN(t)Bu)]; N(p)∩N(i) = 4-tert-butylphenyl(pyrrolato-2-ylmethylene)amine] is obtained in diastereomerically pure form in the solid state, as revealed by single-crystal X-ray diffraction. In solution, this stereoisomer equilibrates with the Δ,Λ-OC-6-2-4 diastereomer 2 at ambient temperature. The stereochemistry of both isomers has been elucidated by NMR, IR, and UV/vis spectroscopy in combination with density functional theory (DFT)/polarizable continuum model and time-dependent DFT calculations. The isomerization 1 → 2 is suggested to proceed via a dissociative trigonal twist with dissociation of the …

DenticityChemistryIsocyanideImineDiastereomerPhotochemistryMedicinal chemistryPolarizable continuum modelDissociation (chemistry)Inorganic Chemistrychemistry.chemical_compoundPhysical and Theoretical ChemistryIsomerizationtert-Butyl isocyanideInorganic chemistry
researchProduct

Solution and solid state studies with the bis-oxalato building block [Cr(pyim)(C2O4)2]− [pyim = 2-(2′-pyridyl)imidazole]

2013

The preparation, X-ray structure, and variable temperature magnetic study of the new compound {Ba(H2O)3/2[Cr(pyim)(C2O4)2]2}n·9/2nH2O (1) [pyim = 2-(2′-pyridyl)imidazole and C2O42− = dianion of oxalic acid], together with the potentiometric and spectrophotometric studies of the protonation/deprotonation equilibria of the pyim ligand and the ternary complex [Cr(pyim)(C2O4)2]−, are reported herein. The crystal structure of 1 consists of neutral chains, with diamond-shaped units sharing barium(II), with the two other corners occupied by chromium(III). The two metal centers are connected through bis(bidentate) oxalate. Very weak antiferromagnetic interactions between the chromium(III) ions occu…

DenticityInorganic chemistrychemistry.chemical_elementProtonationCrystal structureOxalateAcid dissociation constantchemistry.chemical_compoundChromiumCrystallographyDeprotonationchemistryMaterials ChemistryImidazolePhysical and Theoretical ChemistryJournal of Coordination Chemistry
researchProduct

Change of arsenite adsorption mechanism during aging of 2-line ferrihydrite in the absence of oxygen

2018

Abstract Arsenite was effectively immobilized by 2-line ferrihydrite at different pH values (4.0, 5.5 and 7.4) and adsorbent dosages (0.4, 1, and 2 g/L) in the absence of oxygen, showing an initial surface diffusion-controlled period (Stage I, 2 h). Dissolved δ 56 Fe increased during Stage I and decreased during Stage II, resulting from aging of ferrihydrite and equilibrium isotopic exchange, respectively. The ferrihydrite aging was hampered by both high As concentrations and high pH values close to the pH zpc , due to inhibition of mineral dissolution as a prerequisite for mineral transformation. During Stage I, As was adsorbed by both bidentate binuclear corner-sharing ( 2 C ) and monoden…

DenticityMineral010504 meteorology & atmospheric sciencesEnvironmental remediationChemistryInorganic chemistrychemistry.chemical_element010501 environmental sciences01 natural sciencesPollutionOxygenFerrihydritechemistry.chemical_compoundAdsorptionGeochemistry and PetrologyEnvironmental ChemistryDissolution0105 earth and related environmental sciencesArseniteApplied Geochemistry
researchProduct

General route to dissymmetric heteroannular-functionalized ferrocenyl 1,2-diphosphines: selective synthesis and characterization of a new class of tr…

2006

Several monosubstituted-cyclopentadienyl anions (A-Li) and [1,2-bis(diphenylphosphino)-4-tert-butylcyclopentadienyl]lithium (B-Li) react with FeCl2 to afford a novel class of multidentate ferroceny...

Denticitysynthesis010405 organic chemistryChemistryOrganic Chemistry[ CHIM.COOR ] Chemical Sciences/Coordination chemistrychemistry.chemical_elementCharacterization (mathematics)010402 general chemistryligand01 natural sciencesCombinatorial chemistry3. Good health0104 chemical sciencesInorganic Chemistryferrocenylphosphinedissymetrically functionalized ferroceneDiphosphinesmultidentarityOrganic chemistryLithium[CHIM.COOR]Chemical Sciences/Coordination chemistryPhysical and Theoretical ChemistrydiphosphineComputingMilieux_MISCELLANEOUS
researchProduct