Search results for "Effects"
showing 10 items of 2634 documents
Non-alcoholic fatty pancreas disease pathogenesis: a role for developmental programming and altered circadian rhythms.
2013
Objectives Emerging evidence suggests that maternal obesity (MO) predisposes offspring to obesity and the recently described non-alcoholic fatty pancreas disease (NAFPD) but involved mechanisms remain unclear. Using a pathophysiologically relevant murine model, we here investigated a role for the biological clock - molecular core circadian genes (CCG) in the generation of NAFPD. Design Female C57BL6 mice were fed an obesogenic diet (OD) or standard chow (SC) for 6 weeks, prior to pregnancy and throughout gestation and lactation: resulting offspring were subsequently weaned onto either OD (Ob_Ob and Con_Ob) or standard chow (Ob_Con and Con_Con) for 6 months. Biochemical, pro-inflammatory and…
Conformational mobility of thianthrene-5-oxide.
2005
[reaction: see text] Data on the apparent dipole moment of thianthrene-5-oxide (1) and (1)H NMR spectra in different solvents support the conformational mobility of 1, which flaps between two limit boat conformations with the sulfinyl group in pseudoequatorial and pseudoaxial positions, respectively. The conformational equilibrium of 1 occurs too fast for the (1)H NMR (500 MHz) time-scale even at -130 degrees C, and the equilibrium constant has not been determined. The apparent dipole moments of 1 in n-hexane and 1,4-dioxane and the (1)H NMR spectra of 1 and the model compounds cis- and trans-thianthrene-5,10-dioxides (2) and thianthrene (5) in different solvents and at various temperatures…
Constraints on Cosmic Strings Using Data from the Third Advanced LIGO–Virgo Observing Run
2021
We search for gravitational-wave signals produced by cosmic strings in the Advanced LIGO and Virgo full O3 data set. Search results are presented for gravitational waves produced by cosmic string loop features such as cusps, kinks and, for the first time, kink-kink collisions.cA template-based search for short-duration transient signals does not yield a detection. We also use the stochastic gravitational-wave background energy density upper limits derived from the O3 data to constrain the cosmic string tension, $G\mu$, as a function of the number of kinks, or the number of cusps, for two cosmic string loop distribution models.cAdditionally, we develop and test a third model which interpolat…
Non-equilibrium dynamics of a scalar field with quantum backreaction
2021
We study the dynamical evolution of coupled one- and two-point functions of a scalar field in the 2PI framework at the Hartree approximation, including backreaction from out-of-equilibrium modes. We renormalize the 2PI equations of motion in an on-shell scheme in terms of physical parameters. We present the Hartree-resummed renormalized effective potential at finite temperature and critically discuss the role of the effective potential in a non-equilibrium system. We follow the decay and thermalization of a scalar field from an initial cold state with all energy stored in the potential, into a fully thermalized system with a finite temperature. We identify the non-perturbative processes of …
Planck-scale effects on WIMP dark matter
2014
There exists a widely known conjecture that gravitational effects violate global symmetries. We study the effect of global-symmetry violating higher-dimension operators induced by Planck-scale physics on the properties of WIMP dark matter. Using an effective description, we show that the lifetime of the WIMP dark matter candidate can satisfy cosmological bounds under reasonable assumptions regarding the strength of the dimension-five operators. On the other hand, the indirect WIMP dark matter detection signal is significantly enhanced due to new decay channels.
Assessing Master Students' Competencies Using Rubrics: Lessons Learned from Future Secondary Education Teachers
2020
The aim of this paper is to provide insights into the appropriateness of teaching-learning and evaluation processes using rubrics, for student self-assessments. We studied students enrolled on the Master&rsquo
Business Ethics as a Sustainability Challenge: Higher Education Implications
2018
Recent financial scandals worldwide have intensified concern for business (and especially accounting) ethics. Hence, under an overall economic and social sustainability approach, it is crucial to improve the effectiveness of business ethics and corporate social responsibility (CSR) education, in terms of its impact on business students&rsquo
Universities' Reporting on SDGs: Using THE Impact Rankings to Model and Measure Their Contribution to Sustainability
2021
Higher education institutions (HEIs) have voiced growing concerns about sustainability issues since Agenda 2030 was approved, but this is not enough for societal stakeholders seeking and delivering innovation and excellence. The 17 Sustainable Development Goals (SDGs) were adopted by all UN Member States in 2015 as a universal call to action, and pose a challenge for HEIs as for the efforts made to fulfill them and knowing how to assess their performance. However, the metric management system implemented by HEIs quickly led to rankings emerging, which compare HEIs to metrics not related to the sustainability dimensions of the 17 SDGs. The main aim of the paper is to assess the level of repo…
The Future We Want: a Learning Experience to Promote SDGs in Higher Education from the United Nations and University of Valencia
2021
This article shares the strategy for mainstreaming the Sustainable Development Goals (SDGs) at the University of Valencia (UV), which, although limited in its scale, may compel other Higher Education Institutions to think in technological and social progress aligned with the 2030 Agenda. It explicates a process driven by the UV, on the occasion of the 75th anniversary of the United Nations (UN), and in collaboration with the Service for Geospatial, Information, and Telecommunications Technologies from the UN Support Base in Valencia (Spain) to prepare the online event: “The United Nations We Want”. It was the culmination of a collaborative project between students and faculties from differe…
Linked(In)g sport management education with the sport industry: A preliminary study
2021
Social media are one of the most valuable management tools used by sport managers in the fulfilment of their daily tasks. However, the studies that share and analyse the impact of educational experiences that incorporate social media into sport management education for professional purposes are scarce to date. Thus, this study presents an educational innovation piloted in a sport management course where LinkedIn—the social media most associated with the professional sphere—is introduced through an experiential learning methodology, as a driver of students’ career development and as a tool to keep up to date and interact with the sport industry. To assess the learning outcomes, a new scale w…