Search results for "Engineering sciences"
showing 10 items of 2347 documents
Functional characterization of two human olfactory receptors expressed in the baculovirus Sf9 insect cell system
2005
Olfactory receptors (ORs) are the largest member of the G-protein-coupled receptors which mediate early olfactory perception in discriminating among thousands of odorant molecules. Assigning odorous ligands to ORs is a prerequisite to gaining an understanding of the mechanisms of odorant recognition. The functional expression of ORs represents a critical step in addressing this issue. Due to limitations in heterologous expression, very few mammal ORs have been characterized, and so far only one is from human origin. Consequently, OR function still remains poorly understood, especially in humans, whose genome encodes a restricted chemosensory repertoire compared with most mammal species. In …
Improving extracellular vesicles visualization: From static to motion
2020
AbstractIn the last decade, extracellular vesicles (EVs) have become a hot topic. The findings on EVs content and effects have made them a major field of interest in cancer research. EVs, are able to be internalized through integrins expressed in parental cells, in a tissue specific manner, as a key step of cancer progression and pre-metastatic niche formation. However, this specificity might lead to new opportunities in cancer treatment by using EVs as devices for drug delivery. For future applications of EVs in cancer, improved protocols and methods for EVs isolation and visualization are required. Our group has put efforts on developing a protocol able to track the EVs for in vivo intern…
Energetic macroscopic representation and inversion based control of fuel cell in a series hybrid race vehicle system
2020
This paper studies the replacement of engine and generator as range extender in a hybrid racing car with a fuel cell system. A model of the original system of the car using range extender consisting of an internal combustion engine and electric generator has been developed respecting the action-reaction principle used by energetic macroscopic representation (EMR) and its inversion based control (IBC) to organise its subsystems interconnection according to the physical causality. Results from drive tests of the real car on racing circuit are used to validate the model. The objective of this paper is to study the parameterisation and the integration of fuel cell stack components based on this…
Smart Grid Security: A new Approach to Detect Intruders in a Smart Grid Neighborhood Area Network
2016
International audience; In this paper, we propose an efficient and lightweight attack detection mechanism for a smart grid Neighborhood Area Network (NAN) that combine between distributed and centralized intrusion detection. A NAN includes the customers' appliances, smart meters and collectors. The smart meters measure the power consumption of each appliance and the collectors aggregate the measures and forward them to the control center for analysis. Intrusion Detection System (IDS) agents, proposed in our framework, run in a distributed fashion at smart meters level and in a centralized fashion at collector and control center nodes. A combination between a rule-based detection and a learn…
A Trusted Hybrid Learning Approach to Secure Edge Computing
2021
Securing edge computing has drawn much attention due to the vital role of edge computing in Fifth Generation (5G) wireless networks. Artificial Intelligence (AI) has been adopted to protect networks against attackers targeting the connected edge devices or the wireless channel. However, the proposed detection mechanisms could generate a high false detection rate, especially against unknown attacks defined as zero-day threats. Thereby, we propose and conceive a new hybrid learning security framework that combines the expertise of security experts and the strength of machine learning to protect the edge computing network from known and unknown attacks, while minimizing the false detection rat…
Characterization of micromixing in a Continuous Oscillatory Baffled Reactor
2018
International audience; Micromixing is the limiting step in the progress of fast reactions and fast crystallization processes. Micromixing performance of a Nitech© glass COBR has been characterized using the competing parallel iodide-iodate test reactions. Macromixing length was also qualitatively determined by visualization of a tracer. The results show that an increase in the amplitude to baffle space ratio and a decrease of oscillation frequency improves mixing performance.
Radiation effects on optical frequency domain reflectometry fiber-based sensor
2015
International audience; We investigate the radiation effects on germanosilicate optical fiber acting as the sensing element of optical frequency domain reflectometry devices. Thanks to a new setup permitting to control temperature during irradiation, we evaluate the changes induced by 10 keV x rays on their Rayleigh response up to 1 MGy in a temperature range from −40°C up to 75°C. Irradiation at fixed temperature points out that its measure is reliable during both irradiation and the recovery process. Mixed temperature and radiation measurements show that changing irradiation temperature leads to an error in distributed measurements that depends on the calibration procedure. These results …
Heavy-Ion Radiation Impact on a 4Mb FRAM under Different Test Conditions
2015
The impact of heavy-ions on commercial Ferroelectric Memories (FRAMs) is analyzed. The influence of different test modes (static and dynamic) on this memory is investigated. Static test results show that the memory is prone to temporary effects occurring in the peripheral circuitry. Dynamic tests results show a high sensitivity of this memory to heavy-ions.
Bio materials with reclaimed asphalt: from lab mixes properties to non-damaged full scale monitoring and mechanical simulation
2019
Three innovative environmentally friendly pavement materials, designed with 50% of Reclaimed Asphalt and three different biomaterials (2 bio-additivated bitumens and 1 bio-binder), were produced in an industrial plant. These mixes were tested in lab and also at full scale using an Accelerated Pavement Test facility. The asphalt mix viscoelastic properties were measured in lab and their intrinsic viscoelastic response were simulated. These rheological models are used to simulate the pavement mechanical response using both elastic and viscoelastic multilayer codes. Hence, full scale measurement performed during the full scale test at an early stage (without damages) can be compared with these…
An experimental and kinetic modeling study on the oxidation of 1,3-dioxolane
2021
International audience; The modern catalytic or enzymatic advances allow the production of novel biofuel. Among them, 1,3dioxolane can be produced from formaldehyde and ethylene glycol, both can be obtained from biomass. In this study, the oxidation of 1,3-dioxolane is studied at stoichiometric conditions. The ignition delay times of 1,3-dioxolane/O 2 /inert mixtures were measured in a shock tube and in a rapid compression machine at pressures of 20 to 40 bar and temperatures ranging from 630 to 1300 K. The pressure profiles recorded in the rapid compression machine show a first stage of ignition enlightening the influence of the low temperature chemistry of combustion. Furthermore, mole fr…