Search results for "Exit"

Electroencephalography as a Non-Invasive Biomarker of Alzheimer’s Disease: A Forgotten Candidate to Substitute CSF Molecules?

2021

Biomarkers for disease diagnosis and prognosis are crucial in clinical practice. They should be objective and quantifiable and respond to specific therapeutic interventions. Optimal biomarkers should reflect the underlying process (pathological or not), be reproducible, widely available, and allow measurements repeatedly over time. Ideally, biomarkers should also be non-invasive and cost-effective. This review aims to focus on the usefulness and limitations of electroencephalography (EEG) in the search for Alzheimer’s disease (AD) biomarkers. The main aim of this article is to review the evolution of the most used biomarkers in AD and the need for new peripheral and, ideally, non-invasive b…

Very narrow quantum OBDDs and width hierarchies for classical OBDDs

2014

In the paper we investigate a model for computing of Boolean functions - Ordered Binary Decision Diagrams (OBDDs), which is a restricted version of Branching Programs. We present several results on the comparative complexity for several variants of OBDD models. - We present some results on the comparative complexity of classical and quantum OBDDs. We consider a partial function depending on a parameter k such that for any k > 0 this function is computed by an exact quantum OBDD of width 2, but any classical OBDD (deterministic or stable bounded-error probabilistic) needs width 2 k+1. - We consider quantum and classical nondeterminism. We show that quantum nondeterminism can be more efficien…

Wiener-Granger Causality in Network Physiology with Applications to Cardiovascular Control and Neuroscience

2016

Since the operative definition given by C. W. J. Granger of an idea expressed by N. Wiener, the Wiener–Granger causality (WGC) has been one of the most relevant concepts exploited by modern time series analysis. Indeed, in networks formed by multiple components, working according to the notion of segregation and interacting with each other according to the principle of integration, inferring causality has opened a window on the effective connectivity of the network and has linked experimental evidences to functions and mechanisms. This tutorial reviews predictability improvement, information-based and frequency domain methods for inferring WGC among physiological processes from multivariate…

Semantic Complexity in Natural Language

2015

This chapter presents the technical framework that the authors used to define fragments of natural languages and formulate questions as to their semantic complexity. It examines the study of the classical syllogistic and its extensions. It analyzes the semantic complexity of various salient fragments of English. It highlights that the language of argument, featuring transitive verbs, is in an objective sense inferentially no more complex than the language of classical syllogisms exemplified by argument, indeed, the analogous extension featuring ditransitive verbs involves only a modest increase in complexity. On the other hand, the language of argument, which adds relative clauses to the cl…

Software Complexity and Organization of Firms’ Offshoring Activities

2017

How does software complexity shape software providers’ offshoring tasks, and how do such firms organize their offshoring activity? These questions are important, since the global software development market is growing rapidly, offering new opportunities for software managers and entrepreneurs to distribute their activities geographically. Based on a multi-site case study of 12 software firms, we study connections between software complexity and the offshoring strategies selected. Our findings suggest that software firms select a variety of organizational structures for their offshoring activity, and that the selection is shaped by the complexity of the software in question. peerReviewed

New Metropolitan Perspectives Transition with Resilience for Evolutionary Development

2023

This open access book conveys attention to the theme of transition towards resilience and sustainability and its evolutionary perspective that emphasizes the complexity and uncertainty that governments and society are called to address in response to the ongoing challenges. "New Metropolitan Perspective Post COVID Dynamics: Green and Digital Transition, between Metropolitan and Return to Villages’ Perspectives”, 25–27 May 2022, Reggio Calabria, Italy. The papers included in the book are grouped around the following main topics: the envisaged transition towards resilience and sustainability; the relevance of the planning dimension for defining sustainable development pathways and managing co…

Water distribution network robust design based on energy surplus index maximization

2015

The aim of this paper is to show that energy surplus indices, such as resilience index, besides providing a very good indirect measure of water distribution network reliability to be adopted during the design phase, represent also a valuable and effective indicator of the robustness of the network in alternative network scenarios, and can thus be profitably used in condition of future demands uncertainty. The methodology adopted consisted of (I) multi-objective design optimization performed in order to minimize construction costs while maximizing the resilience index; (II) retrospective performance assessment of the alternative solutions of the Pareto front obtained, under demand conditions…

Cracking the Code : The Impact of Orthographic Transparency and Morphological-Syllabic Complexity on Reading and Developmental Dyslexia

2019

An evolutionary Haar-Rado type theorem

2021

AbstractIn this paper, we study variational solutions to parabolic equations of the type $$\partial _t u - \mathrm {div}_x (D_\xi f(Du)) + D_ug(x,u) = 0$$ ∂ t u - div x ( D ξ f ( D u ) ) + D u g ( x , u ) = 0 , where u attains time-independent boundary values $$u_0$$ u 0 on the parabolic boundary and f, g fulfill convexity assumptions. We establish a Haar-Rado type theorem: If the boundary values $$u_0$$ u 0 admit a modulus of continuity $$\omega $$ ω and the estimate $$|u(x,t)-u_0(\gamma )| \le \omega (|x-\gamma |)$$ | u ( x , t ) - u 0 ( γ ) | ≤ ω ( | x - γ | ) holds, then u admits the same modulus of continuity in the spatial variable.

Introduction to the Symposium on Exploring the Complexities of Performance Management

2017

ABSTRACTThe editors of this symposium hope that this collection of articles can help advance the public administration literature stream across the multiple organizational and cultural settings in which these performance management studies were conducted. However, this symposium also focused on articles that can help advance the practice of performance management, where specific recommendations are needed to help public officials collect, analyze, and use meaningful outcome measures specifically for the benefits for making better management and policy decisions.