Search results for "FOOD ALLERGY"
showing 10 items of 44 documents
The future outlook on allergen immunotherapy in children: 2018 and beyond
2018
Abstract Allergen immunotherapy (AIT) is the only currently available immune-modifying and aetiological treatment for patients suffering from IgE-mediated diseases. In childhood, it represents a suitable therapeutic option to intervene during the early phases of respiratory allergic diseases such as rhino-conjunctivitis and asthma, which is when their progression may be more easily influenced. A growing body of evidence shows that oral immunotherapy represents a promising treatment option in children with persistent IgE- mediated food allergy. The efficacy of AIT is under investigation also in patients with extrinsic atopic dermatitis, currently with controversial results. Furthermore, AIT …
685 Food Allergy - Gastro-Esophageal Reflux Disease Association in Infants
2012
Background Cow’s milk allergy is considered to be the first and most common type of allergy during early infancy. Gastro-esophageal reflux disease and cow’s milk allergy are two different diseases with common clinical features. The aim of the study was to evaluate the clinical data in relation with gastroesophageal reflux and cow’s milk allergy in infants. Material and Methods The prospective study includes 36 infants aged between 2–6 months who attended at Pediatric Clinic during the year 2011 for the clinical evocative manifestations of gastroesophageal reflux. Study protocol includes: clinical criteria, familial/personal atopic features, mother diet, duration of breastfeeding, infant for…
IgG, IgA, and IgE Antibodies to Cow Milk Proteins in an Allergy Prevention Study
1991
In the last few years, several trials have been carried out to determine if certain feeding regimens in neonates prevent atopic diseases1–13. In our country, there is a continuing debate about nutritional supplementation of breast milk with hydrolysate formulas: in the first days of life should only newborns at allergy risk8,9,11,14, or should all newborns be fed only breast milk? This age is claimed to be an especially vulnerable period for a sensitization against foreign proteins because of intestinal immaturity and inexperienced gut-associated lymphoid tissue15. A prospective Danish study revealed cases of cow’s milk allergy only among those breastfed infants who had received cow’s milk …
Food Allergy Knowledge, Attitudes and Practices: A Pilot Study of the General Public and Food Handlers
2016
Objective: We have assessed the factors that might improve the free food allergen at the restaurants. In addition, we have compared food handlers knowledge with the general public knowledge about food allergens. Design: Cross-sectional, via questionnaires. Participants: A total of 182 participants (80 food handlers and 102 of general public). Main Outcome Measures: Dependent variables: Food allergy knowledge, attitudes and practices. Analysis: The analysis of variance (ANOVA) and independent t-test. Questionnaires were hand coded and data was analyzed using Statistical Package for Social Sciences (SPSS) version 19.0. Results: The survey showed that food handlers and general public had some …
Hauttestungen mit Nahrungsmittelallergenen
2008
Hauttestungen haben einen zentralen Stellenwert in der Abklarung von Sensibilisierungen bei Nahrungsmittelallergien. Insbesondere der Pricktest stellt eine Routinemethode dar. Allerdings komplizieren instabile Allergene und das Fehlen standardisierter Extrakte das diagnostische Vorgehen bei Verdacht auf eine Nahrungsmittelallergie. Deswegen ist man nach wie vor auf einen Prick-zu-Prick-Test mit nativen Lebensmitteln angewiesen. Indikationen und Kontraindikationen fur eine Hauttestung mit Nahrungsmittelallergenen unterscheiden sich nicht wesentlich von anderen Allergien. Vorsicht ist bei Zustand nach schwerer anaphylaktischer Reaktion und bei bekannter hoher allergener Potenz der Nahrungsmit…
Urticaria in children and adolescents: An updated review of the pathogenesis and management
2018
The present survey represents the latest data on diagnosis and management of childhood urticaria. It has been observed that urticaria occurs less often in children than adults, with symptoms rarely lasting for over 6 weeks. Triggers or aggravating factors can be found only in 21%-55% of cases. Finding autoantibodies in children does not impact a disease prognosis, unlike in adult patients, where the presence of autoantibodies is associated with a more prolonged run of the disease, a more severe prognosis and more intensive treatment methods. The incidence of food allergy equals to 8%-10% of cases. The incidence of Helicobacter Pylori infection in children is lower than that in adults and co…
Evaluation of IGF1 and IGFBP3 during diet therapy in patients affected by food allergy with complex nutritional risk
1996
The seric levels of IGF1 and IGFBP3 and their molar ratio, together with clinical and auxological parameters, have been evaluated in 16 patients (8 males and 8 females), of average age of 11.6±8.66 months, who were suffering from complex food allergy and were subjected to a balanced diet whill excluded the "offending" food. The results, compared "with those of a control population of same age and body surface, have showln a significative reduction of IGF1 and an increase of the molar ratio IGFBP3/IGF1. These observations suggest that, in spite of no significative variation of growth in height and weight, an exclusion diet for a food allergy can reduce the biological activity of some hormona…
Mast cells partly contribute to allergic enteritis development: Findings in two different mast cell-deficient mice
2021
Allergic enteritis (AE) is a gastrointestinal form of food allergy. The presence of mast cells and granulocytes has been detected in the inflamed tissues in AE. In this study, we aimed to elucidate the role of mast cells in AE development using two mast cell-deficient mouse strains: KIT(W-sh/W-sh) bearing the W-sash (W(sh)) inversion mutation and Cpa3Cre/+, which lack mast cells due to Cre-mediated mast cell eradication, were used in an AE experimental model. The development of clinical symptoms (e.g. drop in body temperature and weight loss) were abolished in both strains, whereas inflammatory levels of AE (e.g. villous atrophy, edema, and granulocyte accumulation) were reduced mainly in K…
Management of allergic disease in the elderly: key considerations, recommendations and emerging therapies
2015
The number of people over 65 is increasing around the world. At present, between 5 and 10% of allergic diseases affect the elderly. In particular, rhinitis is increasing worldwide; the presence of high comorbidity makes the therapy of asthma even more complicated. With reference to dermatological allergies, the dryness of the skin favors the onset of allergic contact and atopic dermatitis, while the senescence of mucous membranes and the impaired secretion of polymeric IgA could be linked to food allergy. Overcoming the problem of adverse drug reaction is limited by the diagnostic difficulty in patients taking multiple drugs. In addition, some drugs, such as β-blockers, angiotensin-converti…
Non-celiac wheat sensitivity as an allergic condition: personal experience and narrative review.
2013
Non-celiac wheat sensitivity (NCWS) is a newly described clinical entity characterized by symptoms, which can involve the gastrointestinal tract, the nervous system, the skin, and other organs. There is little data on the pathogenesis of NCWS and it is probable that different pathogenic mechanisms are involved in the different clinical manifestations of the disease. The only common denominator of NCWS "syndrome" is wheat consumption: the symptoms disappear on exclusion of wheat from the diet, and reappear on wheat consumption. The objective of this study was to review our prior data regarding NCWS and to review relevant medical literature regarding NCWS, with particular attention to the hyp…