Search results for "GDO"
showing 10 items of 382 documents
BBE31 from the Lyme disease agent Borrelia burgdorferi, known to play an important role in successful colonization of the mammalian host, shows the a…
2019
Abstract Lyme disease is a tick-borne infection caused by Borrelia burgdorferi sensu lato complex spirochetes. The spirochete is located in the gut of the tick; as the infected tick starts the blood meal, the spirochete must travel through the hemolymph to the salivary glands, where it can spread to and infect the new host organism. In this study, we determined the crystal structures of the key outer surface protein BBE31 from B. burgdorferi and its orthologous protein BSE31 (BSPA14S_RS05060 gene product) from B. spielmanii. BBE31 is known to be important for the transfer of B. burgdorferi from the gut to the hemolymph in the tick after a tick bite. While BBE31 exerts its function by intera…
Laimas slimības ierosinātāja Borrelia burgdorferi ārējās virsmas proteīna BB0663 iegūšana un struktūras analīze
2019
Darba mērķis bija iegūt Laimas slimības izraisītāja Borrelia burgdorferi (B. burgdorgeri) celma B31 ārējās virsmas proteīna BB0663 struktūru un veikt šīs struktūras analīzi, lai iegūtu plašākas zināšanas par baktērijas patoģenēzes mehānismiem. Darba rezultātā BB0663 proteīns tika uzproducēts Escherichia coli šūnās, attīrīts un kristalizēts. Ar rengenstruktūranalīzes palīdzību tika iegūti šī kristāla difrakcijas dati. Izmantojot iegūtos datus, tika noteikta BB0663 proteīna 3D struktūra. Struktūras analīze parādīja, ka B. burgdorferi BB0663 proteīns ir līdzīgs baktērijas Novosphingobium aromaticivorans (N. aromaticivorans) proteīnam, kuram ir noteikta struktūra, bet nav zināma funkcija. Pētīj…
Huvudpersonernas utveckling i tre bokserier för barn och ungdomar
2004
Nel gioco delle giurisdizioni: il Tribunale della Regia Monarchia di Sicilia nel XVII secolo
2020
Le ampie competenze in materia ecclesiastica del re di Sicilia venivano esercitate in ambito giurisdizionale attraverso il Tribunale della Regia Monarchia. I fondamenti di tali prerogative regie furono posti in discussione in modo talvolta ampiamente conflittuale dalla Santa Sede, mentre queste stesse vennero indicate dai “regalisti” come veri e propri attributi della sovranità. Nel XVII secolo, nel quale il Tribunale aveva già una struttura consolidata, gran parte della sua attività fu dedicata a controversie di non elevato rilievo, intraprese solitamente per sfuggire alla ben più rigida giurisdizione ecclesiastica, sfruttando l’ampia possibilità di avocazione. Relativamente alla città di …
La fortificación del Reino de Valencia en la década de1640 a la luz de la revolución militar
2019
This article proposes a study of the traditions in defensive architecture that concurred in the projects designed by Spanish military engineers for the fortification of the Valencian frontier in 1648 and 1649, in the context of the War of Catalonia (1640-1652). For this it is essential to follow the route of the Valencian adaptations to the military revolution in the matter of fortifications throughout the sixteenth century and compare them with those brought to Valencia in 1641 by the Marquis of Leganes and his engineers from the school of Milan.
Reproductive Biology Including Evidence for Superfetation in the European Badger Meles meles (Carnivora: Mustelidae)
2015
The reproductive biology of the European badger (Meles meles) is of wide interest because it is one of the few mammal species that show delayed implantation and one of only five which are suggested to show superfetation as a reproductive strategy. This study aimed to describe the reproductive biology of female Irish badgers with a view to increasing our understanding of the process of delayed implantation and superfetation. We carried out a detailed histological examination of the reproductive tract of 264 female badgers taken from sites across 20 of the 26 counties in the Republic of Ireland. The key results show evidence of multiple blastocysts at different stages of development present s…
Was the Christian conquest of al-Andalus irreversible?
2012
The consideration of the battle of Las Navas de Tolosa as a turning point in history must necessarily be contemplated within the larger framework of the incapacity shown by Andalusi society to oppose the conquering dynamics manifested by the Iberian feudal aristocracies and monarchies since the conquest of Toledo (1085). This is a crucial matter that cannot be seen in isolation from the wider context of the expansion of Latin Christendom. In this regard, the present article suggests a comparison between the disparate fortunes of the Iberian kingdoms and the Latin principalities in the East through the critical assessment of three factors: (i) dissemination of, and role played by the ideolog…
Historia urbana y mezzogiorno de Italia en la Edad Moderna: propuesta de un cuestionario
1998
The history of urbanization has barely been analyzed for the Mezzogiorno in Italy. This has partly been due to the persistence of stereotypes in Italian historiography, and partly due to the current definition of city functions. The article results from a meeting of specialists in Early Modern southern Italian history organized to undertake the rigorous and detailed study of the common features and the differences within the urban systems of the Mezzogiorno, in order to synthesize the specific character of urbanization in southern Italy over the long term. The author outlines the main areas under study and establishes its methodological foundations and first hypotheses.
Vivir como cristianos y pagar como moros: genealogía medieval de la servidumbre morisca en el reino de Valencia
2009
La conversión forzosa de los musulmanes del reino de Valencia, decretada en 1526, no implicó una igualación social entre cristianos «viejos» y «nuevos», ya que se mantuvo la diferencia de estatus que había existido anteriormente. El artículo examina los tres aspectos fundamentales del contenido de dicha diferencia: la intensidad de las rentas soportadas, la imposición de servicios obligatorios y las trabas a la migración interior y exterior; establece sus orígenes en las condiciones de dominación impuestas a la población infiel inmediatamente después de la conquista del siglo XIII, y traza los grandes rasgos de su evolución a lo largo de la Baja Edad Media. Se arguye que esta población estu…