Search results for "GUI"

showing 10 items of 12462 documents

Inguinal Hernia: Crossfire Between the Meshes.

2015

medicine.medical_specialtyInguinal herniabusiness.industrymedicineSurgerymedicine.diseasebusinessSurgeryAbdominal surgeryHernia : the journal of hernias and abdominal wall surgery
researchProduct

Effects of diazinon exposure on cholinesterase activity in different tissues of European eel (Anguilla anguilla).

1996

Cholinesterase (ChE) activity was measured in brain, plasma, and whole eye of Anguilla anguilla experimentally exposed to a sublethal concentration of 0.042 mg/liter (0.50 of the 96-hr LC50) of the organophosphorous pesticide diazinon. Whole eye was the tissue which revealed higher values of ChE activity (8.17 micromol/min/g) in nonexposed animals. Brain, plasma, and whole eye ChE activity of A. anguilla was inhibited at 6, 24, 48, 72, and 96 hr of diazinon exposure. Pesticide induced significant inhibitory effects on the ChE activity of this species ranging from >70% inhibition in brain tissue to >90% in plasma samples. Brain and plasma presented technical difficulties in their collection.…

medicine.medical_specialtyInsecticidesDiazinonHealth Toxicology and MutagenesisMedian lethal doseRetinaToxicologyLethal Dose 50chemistry.chemical_compoundAnguillidaeInternal medicinemedicineAnimalsCholinesterasesTissue DistributionCholinesteraseintegumentary systembiologyPlasma samplesPublic Health Environmental and Occupational HealthBrainGeneral MedicinePesticidebiology.organism_classificationAnguillaPollutionEndocrinologychemistryDiazinonToxicitybiology.proteinSpectrophotometry UltravioletCholinesterase InhibitorsOrganophosphorous pesticideEcotoxicology and environmental safety
researchProduct

In vivo inhibition of AChE activity in the European eel Anguilla anguilla exposed to technical grade fenitrothion.

1998

European eel (Anguilla anguilla) were exposed to sublethal fenitrothion concentrations in a continuous flow-through system for 4 days. Plasma acetylcholinesterase (AChE) activity was evaluated after 2, 8, 12, 24, 32, 48, 56, 72 and 96 h pesticide exposure. AChE activity in the plasma of the eel decreased as concentration of fenitrothion increased. Pesticide induced significant inhibitory effects on the AChE activity of A. anguilla ranging from 51% inhibition at sublethal concentration of 0.02 ppm to 57% inhibition at sublethal concentration of 0.04 ppm. Eel were exposed to both fenitrothion concentrations for 96 h and then allowed a period of recovery in pesticide-free water. Following 1 we…

medicine.medical_specialtyInsecticidesTime FactorsAchéImmunologyFenitrothionToxicologychemistry.chemical_compoundIn vivoInternal medicinemedicineAnimalsPharmacologychemistry.chemical_classificationDose-Response Relationship DrugFenitrothionPesticideAnguillaAcetylcholinesteraselanguage.human_languageEnzymeEndocrinologychemistryToxicitylanguageTechnical gradeAcetylcholinesteraseCholinesterase InhibitorsComparative biochemistry and physiology. Part C, Pharmacology, toxicologyendocrinology
researchProduct

Liver energy metabolism of Anguilla anguilla after exposure to fenitrothion.

1998

This paper deals with the effect of fenitrothion (0.04 mg/liter) on the energy metabolism of the European eel, Anguilla anguilla, and its recovery from intoxication. Various parameters such as glycogen, lactate, proteins, total lipids, and glucose in eel liver and blood were analyzed after 2, 8, 12, 24, 32, 48, 56, 72, and 96 h of fenitrothion exposure. Subsequently, the fish were allowed recovery periods of 8, 12, 24, 48, 72, 96, 144, and 192 h in clean water, and the same parameters were evaluated. Liver glycogen and lipid contents decreased significantly during the exposure, while blood glucose levels increased markedly. Liver and blood lactate values increased during pesticide exposure,…

medicine.medical_specialtyInsecticidesTime FactorsHealth Toxicology and MutagenesisFenitrothionchemistry.chemical_compoundAnguillidaeInternal medicinemedicineAnimalsPollutantGlycogenbiologyPublic Health Environmental and Occupational HealthLiterGeneral MedicineMetabolismFenitrothionPesticidebiology.organism_classificationAnguillaLipid MetabolismPollutionEndocrinologychemistryLiverToxicityEnergy MetabolismWater Pollutants ChemicalEcotoxicology and environmental safety
researchProduct

Italian version of qualiveen-30: Cultural adaptation of a neurogenic urinary disorder-specific instrument

2011

Purpose Qualiveen-30 is a neurological urinary disorder (UD)-specific health-related quality of life (HRQL) instrument, recommended in the European Association of Urology guideline 2008. The objective is to complete the cultural adaptation of Qualiveen-30 into Italian. Materials and Methods One hundred and twenty eight Italian-speaking spinal cord injury (SCI) patients completed Qualiveen-30 and the SF-12 physical and mental component (PC and MC) at enrolment and 4 weeks later. At follow-up, patients also made global ratings of change (GRC) in urinary HRQL (GRC). Results Qualiveen-30 proved reliable (intraclass correlation coefficients of four domains: 0.77–0.90). Correlations with SF-12 an…

medicine.medical_specialtyIntraclass correlationbusiness.industryUrologyUrinary systemGuidelineMulticenter studyQuality of lifePredictive value of testsPhysical therapyMedicineNeurology (clinical)Young adultObserver variationbusinessNeurourology and Urodynamics
researchProduct

Current Status of Epibulbar Anti-glaucoma Drainage Devices in Glaucoma Surgery

2012

SUMMARY Background: The term “glaucoma” covers a hetero geneous group of progressive optic neuropathies that are accompanied by characteristic visual-field defects. Primary open-angle glaucoma, the most common type, progresses insidiously and causes blindness if untreated. All current forms of treatment aim at lowering the intraocular pressure (IOP) in patients whose IOP is elevated. The implantation of anti-glaucoma drainage systems is one of the available options for surgical treatment. Methods: This review is based on pertinent literature retrieved by a selective search, including glaucoma treatment guidelines from Germany and abroad. Results: A paradigm shift is currently underway regar…

medicine.medical_specialtyIntraocular pressuregenetic structuresmedicine.medical_treatmentGlaucomaTrabeculectomyReview ArticlePostoperative ComplicationsGermanyOphthalmologymedicineGlaucoma surgeryHumansTrabeculectomyIn patientDrainageGlaucoma Drainage ImplantsIntraocular PressureRandomized Controlled Trials as Topicbusiness.industryGold standardGeneral Medicinemedicine.diseaseeye diseasesSurgeryPractice Guidelines as Topicsense organsComplicationbusinessGlaucoma Open-AngleFollow-Up StudiesDeutsches Ärzteblatt international
researchProduct

The effect of tacrine on acetylcholine overflow in the heart

1990

Tacrine, 10(-6) M, enhanced the acetylcholine (ACh) overflow evoked in perfused chicken hearts by field stimulation (5 Hz, 1 min) from 183 to 346 pmol g-1 min-1. Increase to the same level were observed after pretreatment with diisopropylfluorophosphate (DFP) as well as after DFP plus 10(-6) M tacrine. Tacrine, 10(-5) M, caused further enhancement with or without DFP up to 851 pmol g-1 min-1. It was concluded that 10(-6) M tacrine enhanced the ACh overflow by choline esterase inhibition, whereas 10(-5) M tacrine caused, in addition, an increase of neuronal ACh release.

medicine.medical_specialtyIsoflurophateGuinea PigsIn Vitro Techniqueschemistry.chemical_compoundIleumInternal medicinemedicineAnimalsCholineAcetylcholine metabolismCholinesterasePharmacologybiologyChemistryMyocardiumHeartAcetylcholineElectric StimulationEndocrinologyMechanism of actionEnzyme inhibitorTacrineTacrinebiology.proteinField stimulationmedicine.symptomChickensAcetylcholinemedicine.drugEuropean Journal of Pharmacology
researchProduct

Sinusoidal endothelial liver cells in vitro release endothelin — Augmentation by transforming growth factorβ and Kupffer cell-conditioned media

1991

Endothelin is the most potent vasoconstrictor peptide known today. Using a radioimmunoassay for endothelin, we measured immunoreactive endothelin in culture media of guinea pig sinusoidal endothelial liver cells and human umbilical vein endothelial cells. A time-dependent release of immunoreactive endothelin by confluent sinusoidal endothelial liver cells in culture was found. Sinusoidal endothelial liver cells produced similar amounts of immunoreactive endothelin as umbilical vein endothelial cells, about 900 pg/microgram DNA per 24 h. In the presence of transforming growth factor beta a dose-dependent increase of immunoreactive endothelin release was measured. The maximal increase of 50% …

medicine.medical_specialtyKupffer CellsGuinea PigsRadioimmunoassayUmbilical veinTransforming Growth Factor betaInternal medicineDrug DiscoverymedicineAnimalsCells CulturedGenetics (clinical)Dose-Response Relationship DrugbiologyChemistryEndothelinsKupffer cellRadioimmunoassayGeneral MedicineTransforming growth factor betaEndothelin 1In vitroEndocrinologymedicine.anatomical_structureLivercardiovascular systembiology.proteinMolecular MedicineFemaleEndothelium VascularEndothelin receptorTransforming growth factorKlinische Wochenschrift
researchProduct

El papel de la dislipemia aterogénica en las guías de práctica clínica.

2016

Background and objective Atherogenic dyslipidaemia is underdiagnosed, undertreated, and under-controlled. The aim of the present study was to assess the positioning of clinical guidelines as regards atherogenic dyslipidaemia. Material and method The major clinical guidelines of scientific societies or official agencies issued between January 1, 2012 and March 31, 2015 were collected from the MEDLINE database. High-density lipoprotein (HDL) cholesterol, triglycerides, atherogenic dyslipidaemia, non-HDL cholesterol, and apolipoprotein (apo) B were gathered from the 10 selected guidelines, and it was assessed whether these parameters were considered a cardiovascular risk factor, a therapeutic …

medicine.medical_specialtyLow HDL-cholesterolendocrine system diseasesApolipoprotein BNice030204 cardiovascular system & hematology03 medical and health scienceschemistry.chemical_compound0302 clinical medicineCardiovascular preventionInternal medicinemental disordersmedicinePharmacology (medical)cardiovascular diseases030212 general & internal medicineRisk factorcomputer.programming_languagebiologybusiness.industryCholesterolnutritional and metabolic diseasesClinical Practicechemistrybiology.proteinlipids (amino acids peptides and proteins)Atherogenic dyslipidaemia Cardiovascular prevention Cholesterol Colesterol Dislipemia aterogénica Guías de práctica clínica Lipids Lípidos Practice guidelines Prevención cardiovascular Triglicéridos TriglyceridesCardiology and Cardiovascular MedicinebusinesscomputerLipoprotein
researchProduct

A case of guillain-barre syndrome in a patient with non small cell lung cancer treated with chemotherapy

2006

Guillain-Barré Syndrome (GBS) is a demyelinating polyneuropathy of probable autoimmune pathogenesis characterized by rapidly progressive symmetric paralysis. In the literature some cases of GBS associated with anticancer chemotherapy are reported. We present a case of a 55-year old woman who complained of progressive motor deficit in four limbs, areflexia in lower limbs and facial nerve paralysis one week after beginning cisplatin-gemcitabine chemotherapy for metastatic lung cancer. The cerebrospinal fluid analysis showed a strong positive Pandy reaction with 435 mg/dl total protein. The electromyography and the electroneuronography established the diagnosis of inflammatory demyelinating po…

medicine.medical_specialtyLung Neoplasmsmedicine.medical_treatmentBone NeoplasmsGuillain-Barre SyndromeDeoxycytidineGastroenterologyPathogenesisCerebrospinal fluidCarcinoma Non-Small-Cell LungInternal medicineAntineoplastic Combined Chemotherapy ProtocolsElectroneuronographyParalysismedicineHumansPharmacology (medical)Lung cancerPharmacologyChemotherapyGuillain-Barre syndromebusiness.industryGuillain-Barré Syndrome neuropathy chemotherapy toxicity lung cancerImmunoglobulins IntravenousMiddle Agedmedicine.diseaseGemcitabineFacial nerveSurgeryInfectious DiseasesOncologyFemaleCisplatinmedicine.symptombusiness
researchProduct