Search results for "Halide"

showing 10 items of 324 documents

Complexes of organometallic compounds

1972

Abstract The novel organobismuth(V) derivatives Ph 3 BiCl(Ox) and Ph 3 BiBr(Ox) (Ox − = 8-quinolinate) have been synthesized, and their configuration investigated in the solid state and in solution. The complexes are assumed to be octahedral in the solid, with Ox − acting as a chelating base and the halide atoms coordinating to bismuth. Tentative assignments of infrared bands in the 300–80 cm −1 region to BiHal and other skeletal modes are proposed. The main effect of solvents appears to be the weakening and breaking of BiN-bonds.

chemistry.chemical_classificationBase (chemistry)InfraredHydrogen bondOrganic ChemistryInorganic chemistryIntermolecular forceSolid-stateHalidechemistry.chemical_elementInfrared spectroscopyGeneral MedicineBiochemistryBismuthInorganic ChemistryOctahedronchemistryAtomPolymer chemistryMaterials ChemistryThalliumChelationPhysical and Theoretical ChemistryGroup 2 organometallic chemistryBioinorganic Chemistry
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Convenient Synthesis of Biologically Important Retinoids

1995

The toxic and teratogenic effects caused by the highly biologically active (all-E)-retinoic acid and its derivatives prompted us to synthesize a number of retinoids. We developed synthetic approaches to (all-E)-retinyl β-D-glucuronide 3, methyl (retinoyl β-D-glucopyranoside)uronate 5, (all-E)-retinoic acid β-D-glucopyranosyl ester 8 and (all-E)-retinoyl β-D-glucuronide 6 in high purity and yield. Compound 3 was synthesized under Koenigs-Knorr conditions from (all-E)-retinol and an α-halogenose. Compounds 5 and 8 were prepared by esterification of a silver salt of (all-E)-retinoic acid with an α-glycosyl halide in pyridine. (all-E)-Retinoyl β-D-glucuronide 6 was prepared by reaction of (all-…

chemistry.chemical_classificationChemistryOrganic ChemistryRetinoic acidHalideSalt (chemistry)Biological activityGeneral ChemistryKoenigs–Knorr reactionchemistry.chemical_compoundYield (chemistry)PyridineOrganic chemistryPhysical and Theoretical ChemistryFluorideLiebigs Annalen
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Synthesis, Spectroscopic, and Structural Investigation of the Cyclic [N(PR2E)2]+ Cations (E = Se, Te; R = iPr, Ph):  the Effect of Anion and R-Group …

2006

Two-electron oxidation of the [N(PiPr2E)2]- anion with iodine produces the cyclic [N(PiPr2E)2]+ (E =Se, Te) cations, which exhibit long E-E bonds in the iodide salts [N(PiPr2Se)2]I (4) and [N(PiPr2Te)2]I (5). The iodide salts 4 and 5 are converted to the ion-separated salts [N(PiPr2Se)2]SbF6 (6) and [N(PiPr2Te)2]SbF6 (7) upon treatment with AgSbF6. Compounds 4-7 were characterized in solution by multinuclear NMR, vibrational, and UV-visible spectroscopy supported by DFT calculations. A structural comparison of salts 4-7 and [N(PiPr2Te)2]Cl (8) confirms that the long E-E bonds in 4, 5, and 8 can be attributed primarily to the donation of electron density from a lone pair of the halide counte…

chemistry.chemical_classificationChemistryStereochemistryDimerIodideHalideNuclear magnetic resonance spectroscopyMedicinal chemistryInorganic Chemistrychemistry.chemical_compoundPhysical and Theoretical ChemistryCounterionLone pairHOMO/LUMODerivative (chemistry)Inorganic Chemistry
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MMX Chains and Molecular Species Containing Rh 2 n+ ( n = 4, 5, and 6) Units: Electrical Conductivity in Crystal Phase of MMX Polymers

2010

The control of the experimental conditions in the reaction of Rh 2 (O 2 CCH 3 ) 4 with halides allows the isolation of the novel dirhodium complexes K x [Rh 2 X(O 2 CCH 3 ) 4 ] x ·4xH 2 O (X = Br, 1·4H 2 O and I, 2·4H 2 O) [Rh 2 (O 2 CCH 3 ) 4 Cl] x H 2 O (3·H 2 O), [Rh 2 (O 2 CCH 3 )Cl] x ·4xH 2 O (3·4H 2 O), and {Rh 2 (O 2 CCH 3 ) 4 I 2 ]· 4H 2 0 (4·4H 2 O) containing Rh 2 n+ (n = 4, 5 and 6) units. The X-ray structure determination of compounds 1-4 reveals the presence of dirhodium units in different oxidation states. The polyanionic complexes 1·4H 2 O and 2·4H 2 O containing Rh 2 4+ units give zig-zag chains. In contrast, the partially oxidized complexes 3·H 2 O and 3·4H 2 O containing …

chemistry.chemical_classificationChemistryStereochemistryIodideHalidechemistry.chemical_elementConductivityChlorideRhodiumInorganic ChemistryCrystalMolecular wireCrystallographymedicineMetal-organic frameworkmedicine.drugEuropean Journal of Inorganic Chemistry
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Lithium enediolates and dienediolates of carboxylic acids in synthesis: Alkylation with secondary halides

1998

Abstract High yields in the alkylation of dianions of α,β-unsaturated carboxylic acids with secondary halides can be obtained despite elimination reactions occurring. α-Regioselectivity for the alkylation of but-2-enoic acids ( 1–4 ) is seldom obtained. Although double bond stereoselectivity is higher than 99% for γ-alkylated products, stereoselectivity is rather poor for most of the α-alkylated products.

chemistry.chemical_classificationDouble bondChemistryOrganic Chemistrychemistry.chemical_elementHalideAlkylationBiochemistryElimination reactionDrug DiscoveryOrganic chemistrylipids (amino acids peptides and proteins)Rather poorStereoselectivityLithiumTetrahedron
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ChemInform Abstract: Lithium Enediolates and Dienediolates of Carboxylic Acids in Synthesis: Alkylation with Secondary Halides.

2010

Abstract High yields in the alkylation of dianions of α,β-unsaturated carboxylic acids with secondary halides can be obtained despite elimination reactions occurring. α-Regioselectivity for the alkylation of but-2-enoic acids ( 1–4 ) is seldom obtained. Although double bond stereoselectivity is higher than 99% for γ-alkylated products, stereoselectivity is rather poor for most of the α-alkylated products.

chemistry.chemical_classificationElimination reactionchemistryDouble bondchemistry.chemical_elementHalidelipids (amino acids peptides and proteins)LithiumStereoselectivityRather poorGeneral MedicineAlkylationMedicinal chemistryChemInform
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Heterogeneously catalyzed Suzuki-Miyaura conversion of broad scope

2012

The reaction tolerates a broad range of functional groups in the coupling partners and is usually performed in solution under homogeneous conditions at T ¢ 60 uC using 2–3 mol% catalytic amounts. The catalyst is often a Pd(0) complex with triarylphosphane ligands. 2 The catalytic cycle (Scheme 2) begins with the oxidative addition of an aryl halide to a Pd(0) species formed in situ to form an arylpalladium(II) halide intermediate. 3 Chloroarenes, especially nonactivated aryl chlorides, are notoriously less reactive due to the stability of the C–Cl bond (the relative reactivity of Ar–X is correlated to the respective bond dissociation energy: Ph–Cl: 96 kcal mol 21 ,P h–Br: 81 kcal mol 21 ,P …

chemistry.chemical_classificationGeneral Chemical EngineeringAryl halideArylchemistry.chemical_elementHomogeneous catalysisGeneral ChemistryOxidative additionCatalysiscross-coupling heterogeneous catalysis palladium Suzuki–Miyaurachemistry.chemical_compoundchemistryCatalytic cycleOrganic chemistryReactivity (chemistry)Palladium
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Solid state halogen bonded networks vs. dynamic assemblies in solution: explaining N⋯X interactions of multivalent building blocks

2015

Tetrapyridine functionalized resorcinarene macrocycles were used as multivalent building blocks for the construction of halogen bonded networks with aryl halide linkers. In the solid state, resorcinarene macrocycles and aryl halide linker molecules assembled into interpenetrated, multidimensional halogen bonded networks with porous structure caused by the 3D block scaffold of the resorcinarenes. 19F NMR spectroscopy proved halogen bond formation also in solution, as either upfield or downfield shifts were observed depending on the bivalent or monovalent halogen bond binding mode. The binding mode in solution was explained by density functional theory computations. peerReviewed

chemistry.chemical_classificationHalogen bondta114ChemistryStereochemistryAryl halideSolid-stateGeneral ChemistryResorcinareneCondensed Matter PhysicsCrystallographyhalogen bonded networksHalogenMoleculeGeneral Materials ScienceDensity functional theoryta116Linkerresorcinarene macrocyclesaryl halide linkers
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Self-assembling resorcinarene capsules: solid and gas phase studies on encapsulation of small alkyl ammonium cations

2002

The self-assembling process of unsubstituted resorcinarenes (1, 2 and 3) to dimeric capsules encapsulating small tetra-alkyl ammonium cations 4–7 has been studied in solid and gaseous states by X-ray crystallographic and mass spectrometric methods. Hydrogen bonding and cation-π interaction as well as the proper encapsulation in the empty cavity of the capsule appear to be the most important interactions in the capsule formation process. Competitive mass spectrometric studies clearly indicated preference of the tetramethyl ammonium cation (4) over tetraethyl ammonium cation (6) and especially tetrabutyl ammonium cation (7). The crystal structures of altogether eight dimeric capsules of resor…

chemistry.chemical_classificationHydrogen bondInorganic chemistryHalideGeneral ChemistryCrystal structureResorcinareneCatalysisGas phaseIonchemistry.chemical_compoundchemistryPolymer chemistryMaterials ChemistryAmmoniumAlkylNew Journal of Chemistry
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Isolation of a stable, acyclic, two-coordinate silylene.

2012

The synthesis and characterization of a stable, acyclic two-coordinate silylene, Si(SAr(Me(6)))(2) [Ar(Me(6)) = C(6)H(3)-2,6(C(6)H(2)-2,4,6-Me(3))(2)], by reduction of Br(2)Si(SAr(Me(6)))(2) with a magnesium(I) reductant is described. It features a V-shaped silicon coordination with a S-Si-S angle of 90.52(2)° and an average Si-S distance of 2.158(3) A. Although it reacts readily with an alkyl halide, it does not react with hydrogen under ambient conditions, probably as a result of the ca. 4.3 eV energy difference between the frontier silicon lone pair and 3p orbitals.

chemistry.chemical_classificationHydrogenSiliconMagnesiumSilyleneHalidechemistry.chemical_elementGeneral ChemistryPhotochemistryBiochemistryCatalysischemistry.chemical_compoundCrystallographyColloid and Surface ChemistryAtomic orbitalchemistryLone pairta116AlkylJournal of the American Chemical Society
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