Search results for "Humor"
showing 10 items of 220 documents
Efficacy of a bivalent vaccine against eel diseases caused by Vibrio vulnificus after its administration by four different routes
2003
Vulnivaccine, a vaccine against vibriosis caused by Vibrio vulnificus serovar E (formerly biotype 2), confers acceptable levels of protection to eels after its administration by prolonged immersion in three doses. Recently, a new pathogenic serovar, named serovar A, has been isolated from vaccinated eels in a Spanish freshwater eel farm. The main objective of this work was to design a bivalent vaccine, and to study its effectiveness against the two pathogenic serovars. With this aim, eels weighing around 20 g were immunised with the bivalent vaccine by oral and anal intubation, intraperitoneal injection (i.p.) and prolonged immersion. The overall results indicated that: (i) the new vaccine …
A case of visceral leishmaniasis and pulmonary tuberculosis in a post-partum woman
2015
AbstractVisceral leishmaniasis due to Leishmania infantum is a vector-borne zoonotic disease transmitted by sand fly bites endemic in rural or periurban areas of the Mediterranean basin. Pregnancy is accompanied by changes in immune response, mainly a decrease in cellular immunity and a proportional increase in humoral immunity. These physiological events result in increased risk of infection by pathogens whose immunity is based on a T-helper 1 predominant response. We describe a case of visceral leishmaniasis and pulmonary tuberculosis diagnosed in a post-partum woman four days after delivery. The diagnosis of leishmaniasis should be considered in pregnant women with fever and haematologic…
Serologic Response to Cell Wall Mannoproteins and Proteins of Candida albicans
1998
SUMMARY The cell wall of Candida albicans not only is the structure in which many biological functions essential for the fungal cells reside but also is a significant source of candidal antigens. The major cell wall components that elicit a response from the host immune system are proteins and glycoproteins, the latter being predominantly mannoproteins. Both the carbohydrate and protein moieties are able to trigger immune responses. Although cell-mediated immunity is often considered to be the most important line of defense against candidiasis, cell wall protein and glycoprotein components also elicit a potent humoral response from the host that may include some protective antibodies. Prot…
New insights into autoantibody profiles from immune privileged sites in the eye: a glaucoma study.
2011
Glaucoma is a chronic neurodegenerative disease and one of the leading causes of blindness. Autoantibody based immune processes are assumed to be involved in its pathogenesis. However, it is still unclear to what extent autoantibody patterns found in the eye (aqueous humor) are congruent to systemic autoantibodies (blood). Consistency would underline the specificity of known serum antibody markers for glaucoma. In this study we used antigen microarrays to analyze autoantibody reactivities in sera and corresponding aqueous humor samples of primary open-angle glaucoma patients (N=37) and non-glaucomatous controls (N=31). Compared to control subjects several divergent immunoreactivities were i…
Humors „Laipni lūdzam Nakts ielejā” (Welcome to Night Vale) aplādēs
2018
Daiļliteratūrā humoru rada dažādi lingvistiskie un stila izteiksmes līdzekļi, no kuriem vairums ir plaši izpētīts. Tomēr mūsdienās popularitāti ir guvis jauns komisku stāstu prezentēšanas formāts – interneta radio aplāde – kura stilistiskās un stāstījuma īpatnības joprojām tiek pētītas salīdzinoši minimāli. Tādēļ šī darba mērķis ir noskaidrot kā humors tiek veidots komēdijas aplādē „Laipni lūdzam nakts ielejā” (Welcome to Night Vale). Lai to panāktu, tika veikta četru „Laipni lūdzam nakts ielejā” epizožu tekstu analīze. Pētījums atklāj, ka humoru šajā aplādē lielākoties veido hiperbolas, epiteti, atkārtošanās un paradokss. Katrs no šiem stila izteiksmes līdzekļiem sagroza komunikācijas norm…
Elaboracion y validación de un programa de intervención para mejorar la resiliencia en adolescentes dominicanos en situación de riesgo
2015
RESUMEN La elaboración y validación de un programa de intervención para mejorar la resiliencia en adolescentes dominicanos en situación de riesgo, se ha realizado mediante un diseño descriptivo (grupo1) y cuasi experimental (grupo 2, tratamiento y control). El grupo 1 compuesto por una muestra de 400 adolescentes dominicanos, con edades comprendidas entre 12 y 16 años, escolarizados en centros educativos públicos y privados. El grupo 2, estuvo integrado por 75 adolescentes, de los cuales 20 (tratamiento) participaron en la intervención del programa READOM y a 55 (control) se les aplica un pre y postest. En el estudio, son validadas las Escala de Resiliencia de Connor-Davidson, utilizando co…
Moljēra komēdijas “Vidusšķiras augstmanis” tulkošanas stratēģijas
2017
Maģistra darba mērķis ir iztulkot Moljēra muzikālo komēdiju “Vidusšķiras augstmanis” latviešu valodā un izanalizēt tulkošanas procesā lietotās tulkošanas stratēģijas. Ļoti maz Moljēra lugu ir tulkotas latviešu valodā, un neviens tulkojums nav veikts 21. gadsimtā, tāpēc šajā laukā ir plašas izpētes iespējas. Darbs sastāv no lugas tulkojuma un šī tulkojuma analīzes. Galvenās tulkojuma metodes ir teorētiskās literatūras analīze un tulkojuma teksta sistēmiska analīze. Moljēra muzikālās komēdijas tulkojumā izmantots plašs dāžādu tulkošanas stratēģiju spektrs, ko var apskatīt gan vispārīgi (piem., arhaizēšana), gan arī atsevišķu elementu kontekstā (humora, reāliju, īpašvārdu u. tml. elementu tulk…
Disrupting immune regulation incurs transient costs in male reproductive function.
2014
9 pages; International audience; BACKGROUND: Immune protection against pathogenic organisms has been shown to incur costs. Previous studies investigating the cost of immunity have mostly focused on the metabolic requirements of immune maintenance and activation. In addition to these metabolic costs, the immune system can induce damage to the host if the immune response is mis-targeted or over-expressed. Given its non-specific nature, an over-expressed inflammatory response is often associated with substantial damage for the host. Here, we investigated the cost of an over-expressed inflammatory response in the reproductive function of male mice. METHODOLOGY/PRINCIPAL FINDINGS: We experimenta…
Biological responses of Rhynchophorus ferrugineus (Coleoptera: Curculionidae) to Steinernema carpocapsae (Nematoda: Steinernematidae).
2013
Rhynchophorus ferrugineus (Olivier 1790) (Coleoptera: Curculionidae) is becoming a serious problem in Mediterranean areas where it is well-adapted, and now is present even in the United States (California). The infestations are primarily in urban areas where chemical control is not advisable and million of Euros are spent to control it. The effects of the entomopathogenic nematode Steinernema carpocapsae (Nematoda: Steinernematidae) on mortality, growth, as well as the immune activity of R. ferrugineus larvae, were investigated. R. ferrugineus mortality exhibited a positive trend with the dosage and duration of exposure to S. carpocapsae. The median lethal dose and median lethal time, impor…
Altered antioxidant-oxidant status in the aqueous humor and peripheral blood of patients with retinitis pigmentosa.
2013
Retinitis Pigmentosa is a common form of hereditary retinal degeneration constituting the largest Mendelian genetic cause of blindness in the developed world. It has been widely suggested that oxidative stress possibly contributes to its pathogenesis. We measured the levels of total antioxidant capacity, free nitrotyrosine, thiobarbituric acid reactive substances (TBARS) formation, extracellular superoxide dismutase (SOD3) activity, protein, metabolites of the nitric oxide/cyclic GMP pathway, heme oxygenase-I and inducible nitric oxide synthase expression in aqueous humor or/and peripheral blood from fifty-six patients with retinitis pigmentosa and sixty subjects without systemic or ocular …