Search results for "Humor"

Classical Flt3L-dependent dendritic cells control immunity to protein vaccine

2014

DCs are critical for initiating immunity. The current paradigm in vaccine biology is that DCs migrating from peripheral tissue and classical lymphoid-resident DCs (cDCs) cooperate in the draining LNs to initiate priming and proliferation of T cells. Here, we observe subcutaneous immunity is Fms-like tyrosine kinase 3 ligand (Flt3L) dependent. Flt3L is rapidly secreted after immunization; Flt3 deletion reduces T cell responses by 50%. Flt3L enhances global T cell and humoral immunity as well as both the numbers and antigen capture capacity of migratory DCs (migDCs) and LN-resident cDCs. Surprisingly, however, we find immunity is controlled by cDCs and actively tempered in vivo by migDCs. Del…

Vizuālās metaforas karikatūrās: Gata Šļūkas zīmēto karikatūru semiotiskā analīze (delfi.lv, gatissluka.com, la.lv un skats.lv karikatūru arhīvs, 2010…

2016

Bakalaura darbs “Vizuālās metaforas karikatūrās: Gata Šļūkas zīmēto karikatūru semiotiskā analīze (delfi.lv, gatissluka.com, la.lv un skats.lv karikatūru arhīvs, 2010 - 2015)” pētījuma problēma ir karikatūru kā reprezentācijas un informācijas nesēja loma, izmantojot vizuālās metaforas. Pētījums balstīts uz divām pamata teorētiskajām pieejām – semiotisko kontentanalīzi, ar kuras palīdzību tiek analizētas karikatūras un semiotiskās iezīmes atsevišķās kategorijās, kā arī auditorijas aptauja interneta vidē, kuras laikā tiks noskaidrots respondentu viedoklis par karikatūru nozīmi komunikācijā, kā arī to vērtējums dažādās jomās. Pētījuma galvenais mērķis ir izpētīt karikatūrās izmantotās vizuālās…

Funcionamiento Neuropsicológico en el Trastorno Bipolar: Estabilizadores del Humor y Benzodiacepinas

2021

Introducción El trastorno bipolar (TB) es considerado por la Organización Mundial de la Salud como uno de los problemas de salud más urgentes a nivel mundial y una de las veinte principales causas de discapacidad. Su principal característica es la alternancia de episodios maniacos y episodios depresivos con periodos de estabilidad clínica. Por otro lado, está bien establecida la presencia de disfunciones neurocognitivas en pacientes con trastorno bipolar, asociadas a factores clínicos, tales como el número de episodios afectivos y hospitalizaciones, la duración de la enfermedad, y pobre ajuste psicosocial a largo plazo. Sin embargo, el curso longitudinal del TB es muy variable, y un subgrup…

Britu un amerikāņu humora pragmatiskā nozīme svešvalodas lietotāja skatījumā

2017

Bakalaura darbs pēta britu un amerikāņu humora pragmatisko nozīmi svešvalodas lietotāja skatījumā. Darba mērķis ir analizēt, kā humora sociokulturālais konteksts ietekmē netiešo nozīmi svešvalodas lietotāja skatījumā. Darba teorētiskā daļa aplūko pragmatiku kā lingvistikas nozari ar uzsvaru uz pragmatisko kļūdu, turklāt teorētiskā daļa apskata arī humora konceptu. Darba praktiskā daļa ir sadalīta divos soļos. Pirmkārt, pragmatiskās nozīmes analīze izvēlētos britu un amerikāņu humora piemēros. Un otrkārt, fokusa grupu diskusijas, kur to dalībniekiem tika lūgts izskaidrot pragmatisko nozīmi izvēlētajos piemēros. Rezultāti atklāj, ka svešvalodas lietotāji labāk izprot amerikāņu humoru, jo brit…

A Practical Joke in Public Sphere – a Polish Case Study

2017

The aim of the paper is to show multiple layers of discourse and the consequences of a particular practical joke that has been played at a local public event and has become a theme for media coverage nationwide. Students in one of Polish high schools brought a goat as a present to their headmaster and handed it in during their commencement ceremony. Some event participants reported it to the Animal Welfare Society claiming that the goat was mistreated. It seemed that it was not eager to be led on a leash and it urinated, which was interpreted as a sign of discomfort and stress. The story became a headline first in the local and then in the national press and television, and was accompanied …

Papel de estraza : periódico ecléctico dedicado á la posteridad.

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Viral proteins VP2, VP6, and NSP2 are strongly precipitated by serum and fecal antibodies from children with rotavirus symptomatic infection

1998

Rotavirus-specific IgA has been correlated with immune protection against rotavirus reinfection and symptomatic disease. Systemic and mucosal antibody responses were determined by an enzyme-linked immunosorbent assay in 11 infants with severe rotavirus gastroenteritis. Geometric mean titers of antirotavirus serum IgG and IgA antibodies were significantly higher during the convalescence of the disease (P < 0.001 vs. acute-phase titers). Rotavirus-specific fecal sIgA antibodies increased 4 times during the convalescence in 9 (81.8%) children (P < 0.001). The serum IgG and IgA antibody and fecal sIgA antibody responses to individual rotavirus polypeptides were characterized by radioimmunopreci…

Psychometric Comparisons of Benevolent and Corrective Humor across 22 Countries: The Virtue Gap in Humor Goes International

2018

All authors: Sonja Heintz, Willibald Ruch, Tracey Platt, Dandan Pang, Hugo Carretero-Dios, Alberto Dionigi, Catalina Argüello Gutiérrez, Ingrid Brdar, Dorota Brzozowska, Hsueh-Chih Chen, Władysław Chłopicki, Matthew Collins, Róbert Ďurka, Najwa Y. El Yahfoufi, Angélica Quiroga-Garza, Robert B. Isler, Andrés Mendiburo-Seguel, TamilSelvan Ramis, Betül Saglam, Olga V. Shcherbakova, Kamlesh Singh, Ieva Stokenberga, Peter S. O. Wong and Jorge Torres-Marín.

Mechanisms underlying lineage commitment and plasticity of human γδ T cells.

2012

Phenotypic and functional heterogeneity are the hallmarks of effector and memory T cells. Upon antigen stimulation, γδ T cells differentiate into two major types of memory T cells: central memory cells, which patrol the blood and secondary lymphoid organs, and effector memory cells, which migrate to peripheral tissues. γδ T cells display in vitro a certain degree of plasticity in their function that is reminiscent of that which is observed in conventional CD4 T cells. Similar to CD4 T cells, in which a plethora of specialized subsets affect the host response, γδ T cells may readily and rapidly assume distinct Th1-, Th2-, Th17-, T(FH) and T regulatory-like effector functions, suggesting that…

Risa, género y políticas de celebridad en España: En torno a Emilia Pardo Bazán

2022

Este texto analiza las relaciones que existen entre las prácticas relacionadas con la celebridad literaria femenina, el uso del humor y las políticas de género en la España del último tercio del siglo XIX. El análisis se enfoca a través de las experiencias al respecto, y su repercusión pública, por parte de una escritora, Emilia Pardo Bazán, en cuya celebridad particular el humor y los estereotipos de género desempeñaron un papel central. Horizon 2020/ERC-2017-Advanced Grant-787015 This text analyzes the relationships that exist between practices related to female literary celebrity, the use of humor and gender politics in Spain in the last third of the nineteenth century. The analysis is a…