Search results for "I.5"
showing 10 items of 399 documents
Widgit simbolu izmantošana priekšējo mēleņu R un L izrunas traucējumu novēršanai 5 – 7 gadīgiem bērniem
2020
Diplomdarba tēma: Widgit simbolu izmantošana priekšējo mēleņu [R] un [L] izrunas traucējumu novēršanai 5 – 7 gadīgiem bērniem. Darba autore: Eva Grīnberga. Darba zinātniskā vadītāja: Mg. paed. Ilze Vilka. Darba apjoms: 78 lappuses, 11 tabulas, 10 attēli, ievads, 3 nodaļas ar apakšnodaļām, izmantotās literatūras saraksts ar 64 vienībām, secinājumi, priekšlikumi, 13 pielikumi. Pētījuma mērķis: teorētiski izzināt un praktiski pārbaudīt Widgit simbolu izmantošanas efektivitāti koriģējoši attīstošā darbībā priekšējo mēleņu [L] un [R] izrunas traucējumu novēršanā 5 – 7 gadus veciem bērniem. Pētījuma uzdevumi: 1.Analizēt pedagoģiskās, psiholoģiskās teorētiskās atziņas par 5 – 7 gadīgu bērnu runas …
Halogen and Hydrogen Bonded Complexes of 5-Iodouracil
2013
Three derivatives of 5-iodouracil were prepared, and their complexation properties, supplemented by 5-iodouracil under the same conditions, were studied with and without halogen bond acceptors in N,N-dimethylformamide, N,N-diethylformamide, N-methylformamide, formamide, dimethylsulfoxide, and water. The intermolecular halogen and hydrogen bonding interactions observed in the solid state were investigated using single crystal X-ray diffraction and quantum chemical calculations, and the acquired data were contrasted with bonding interactions previously reported for 5-iodouracil in the Cambridge Structural Database. It was found that the polarized iodine atom and the amidic NH functionality ac…
Isolation and purification of enniatins A, A1, B, B1, produced by Fusarium tricinctum in solid culture, and cytotoxicity effects on Caco-2 cells
2010
Enniatins (ENs) are antibiotic compounds of hexadepsipeptidic structure produced by several strains of Fusarium spp. The ENs A, A(1), B, B-1 were purified from extracts of Fusarium tricinctum grown on a solid medium of corn, by a low pressure liquid chromatography (LPLC) on reverse phase of Amberlite XAD-7 followed by semipreparative LC. The purity and the structure of the isolated compounds were confirmed by LC-MS/MS. The technique of the purification of the fungal extract enabled complete separation of the ENs A, A(1), B, B-1 with a mean purity of 97% for all the compounds. The cytoxicity of the ENs was tested in the cell lines of human origin (epithelial colorectal adenocarcinoma cells, …
Isolactarane and Sterpurane Sesquiterpenoids from the Basidiomycete Phlebia uda
2012
Three new sesquiterpenoids, named udasterpurenol A, udalactarane A, and udalactarane B, as well as the known compounds hyphodontal and sterpuric acid have been isolated from the basidiomycete Phlebia uda. These compounds represent the first natural products described from this species. The structures were elucidated by NMR spectroscopy and mass spectrometry. Udalactaranes A and B were isolated as mixtures with their respective epimeric acetals. These mixtures inhibited the spore germination of the plant pathogenic fungus Fusarium graminearum at 10 and 5 μg/mL, respectively, and were active against Jurkat cells with IC(50) values of 101 and 42 μM, respectively.
Highly potent artemisinin-derived dimers and trimers: Synthesis and evaluation of their antimalarial, antileukemia and antiviral activities
2015
New pharmaceutically active compounds can be obtained by modification of existing drugs to access more effective agents in the wake of drug resistance amongst others. To achieve this goal the concept of hybridization was established during the last decade. We employed this concept by coupling two artemisinin-derived precursors to obtain dimers or trimers with increased in vitro activity against Plasmodiumfalciparum 3D7 strain, leukemia cells (CCRF-CEM and multidrug-resistant subline CEM/ADR5000) and human cytomegalovirus (HCMV). Dimer 4 (IC50 of 2.6 nM) possess superior antimalarial activity compared with its parent compound artesunic acid(3) (IC50 of 9.0 nM). Dimer5 and trimers6 and 7 disp…
Framing Social Work Discourses of Violence Against Women. Insights From Finland and India
2021
Violence against women (VAW) is a global social problem. In India, its high prevalence is connected to gender inequality, whereas Finland suffers from the so-called Nordic Paradox—that is, the existence of both gender equality and a high prevalence of VAW. This qualitative study employed a critical constructioniist approach and frame analysis to analyze data from interviews with Finnish (n =20) and Mumbai (n =18) social workers. We asked how social workers frame their response to VAW and how ways of framing elucidate institutional practices that facilitate the interventions. Anti-oppressive, juridical, procedural, and collaborational frames revealed institutional practices mirroring how soc…
"Strålende samhold" : en analyse av hvordan lærebøker for den videregående skole mellom 1945 og 2008 har fremstilt landssvik og hvordan dette har end…
2012
Masteroppgave i historie- Universitetet i Agder, 2012
Mer enn summen av delene Offshoreleverandørene i Kristiansandsområdet 1972-1986
2015
Masteroppgave historie- Universitetet i Agder, 2015
Atomkrigsforestillinger og krigsfrykt i avisen Fra Tsjekkoslovakia til Cuba-krisen En studie av norske aviser under den kalde krigen i perioden 1948 …
2014
Masteroppgave historie- Universitetet i Agder, 2014
Bruk av plantevernmiddel i Noreg frå 1945 til 2000
2015
Masteroppgave historie- Universitetet i Agder, 2015