Search results for "I.5"

showing 10 items of 399 documents

The Effects of Banning Smartphone Use During Lectures in High Schools : An explanatory case study

2021

Master's thesis in Information systems (IS501) Research context–During the last decade, smartphonehas become an integral part of our lives. It is undeniable that the smartphone has impacted almost every aspect of our lives, and education is no exception. Banning smartphone use is one of the measures that has been implemented in high school to manage excessive smartphone use among students. Developing an appropriate policy to manage smartphone use during lectures can be a difficult task, because it can have a positive impact on their attention and academic performance, while also having a negative impact on their behavior and mentality. Purpose-This study addresses the issue regarding smartp…

ComputerSystemsOrganization_MISCELLANEOUSComputingMilieux_COMPUTERSANDEDUCATIONIS501VDP::Samfunnsvitenskap: 200::Pedagogiske fag: 280VDP::Samfunnsvitenskap: 200::Sosiologi: 220
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Inhibition of Efavirenz Metabolism by Sertraline and Nortriptyline and Their Effect on Efavirenz Plasma Concentrations.

2015

ABSTRACT Between 22 and 45% of HIV-positive subjects are likely to report symptoms of depression. Considering this background, a potential pharmacokinetic interaction between the nonnucleoside reverse transcriptase inhibitor efavirenz (EFV) and two antidepressants, sertraline (SRT) and nortriptyline (NT), was studied. Rats were administered EFV alone or together with the antidepressants, and changes in the plasma levels and pharmacokinetic parameters of EFV were analyzed. Additional in vitro experiments with rat and human hepatic microsomes were carried out to evaluate the inhibitory effect of SRT and NT on EFV metabolism by determining the formation rate of the major EFV metabolite (8-OH-E…

CyclopropanesMalemedicine.medical_specialtyEfavirenzAnti-HIV AgentsMetaboliteNortriptylinePharmacology030226 pharmacology & pharmacy03 medical and health scienceschemistry.chemical_compound0302 clinical medicinePharmacokineticsIn vivoInternal medicineSertralinemedicineAnimalsHumansPharmacology (medical)Drug Interactions030212 general & internal medicineRats WistarIC50PharmacologyChemistryAntidepressive AgentsBenzoxazinesInfectious DiseasesEndocrinologyAlkynesMicrosomeMicrosomes LiverReverse Transcriptase InhibitorsNortriptylinehuman activitiesDrug metabolismmedicine.drugAntimicrobial agents and chemotherapy
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Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium:an application of I…

2014

Mega- or meta-analytic studies (e.g. genome-wide association studies) are increasingly used in behavior genetics. An issue in such studies is that phenotypes are often measured by different instruments across study cohorts, requiring harmonization of measures so that more powerful fixed effect meta-analyses can be employed. Within the Genetics of Personality Consortium, we demonstrate for two clinically relevant personality traits, Neuroticism and Extraversion, how Item-Response Theory (IRT) can be applied to map item data from different inventories to the same underlying constructs. Personality item data were analyzed in >160,000 individuals from 23 cohorts across Europe, USA and Australia…

DIMENSIONSDISORDERS515 PsychologyeducationPersonality AssessmentGenome-wide association studiesExtraversion PsychologicalNEO-PI5-FACTOR MODELGeneticsHumansGenetics(clinical)Ecology Evolution Behavior and SystematicsOriginal ResearchNeuroticismMeasurementNeurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7]Models StatisticalOther Research Radboud Institute for Health Sciences [Radboudumc 0]GENOME-WIDE METAANALYSISTEMPERAMENTASSOCIATIONAnxiety Disorders3142 Public health care science environmental and occupational healthMeta-analysisPhenotypeMEASUREMENT INVARIANCECLONINGERSUrological cancers Radboud Institute for Health Sciences [Radboudumc 15]REPLICATIONDevelopmental PsychopathologyItem-Response TheoryConsortiumGenome-Wide Association StudyPersonality
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Analysis of Chlorpyrifos in Water, Fruit Juice, and Honeybee Extract by Chemiluminescent Elisa

2008

Abstract The suitability of competitive enzyme-linked immunosorbent assays (ELISAs) with chemiluminescent detection-based immobilized antigen (indirect assay) for rapid and accurate determination of chlorpyrifos in various food matrices was tested. The limit of detection (LOD) values were 1–1.75 ng mL−1, the standard curve midpoint (IC50) was 3.5 ng mL−1, and the assay duration was 1.5 h. Assay application to the analysis of honeybee extract resulted in chlorpyrifos recoveries varying between 62 and 83% in 5–15 ng mL−1 herbicide concentration range.

Detection limitChromatographyChemistryBiochemistry (medical)Clinical BiochemistryFOOD/FRUIT JUICESBiochemistryCHEMILUMINESCENCECHLORPYRIFOSAnalytical Chemistrylaw.inventionStandard curveHONEYBEEchemistry.chemical_compoundlawChlorpyrifosElectrochemistryELISAFruit juiceIC50SpectroscopyChemiluminescenceAnalytical Letters
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Ungdom og e-demokrati : hvilke ønsker og forventninger har ungdom til e-demokrati?

2007

Masteroppgave i informasjonssystemer 2007 - Høgskolen i Agder, Kristiansand E-demokrati er et satsningsområde i offentlig sektor. Det har i Norge vært synkende deltagelse i valg både til Storting og kommunevalg ved de siste valgene. Ungdom i aldersgruppen 18 til 21 år har lavere oppslutning rundt valgene enn eldre aldersgrupper. Flere mener at e-demokrati kan bidra til å øke oppslutning rundt demokratiet og valgene. I denne sammenheng er ungdom en viktig målgruppe. Vi har sett nærmere på e-demokrati rettet mot ungdom. Målet for denne masteroppgaven har vært å forstå hvilke ønsker og forventninger ungdom har til informasjonssystemer innen for edemokrati. For å besvare dette spørsmålet har vi…

E-demokratiEvalueringWAEUIS501UngdomWAREVDP::Samfunnsvitenskap: 200::Statsvitenskap og organisasjonsteori: 240::Offentlig og privat administrasjon: 242VDP::Matematikk og naturvitenskap: 400::Informasjons- og kommunikasjonsvitenskap: 420::Systemutvikling og -arbeid: 426
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Coscinolactams A and B: new nitrogen-containing sesterterpenoids from the marine sponge Coscinoderma mathewsi exerting anti-inflammatory properties

2009

Abstract Investigation of the marine sponge Coscinoderma mathewsi led to the isolation of two novel nitrogen-containing cheilanthane sesterterpenoids, coscinolactams A and B, together with known suvanine. The structures were elucidated by extensive spectroscopic measurements including NOE experiments to deduce the stereochemistry. The natural compounds, as well as a semisynthetic derivative, showed moderate anti-inflammatory activity measured as their capability to inhibit PGE2 and NO production. The suvanine aldehyde derivative 4 inhibited inducible nitric oxide protein expression with an IC50 value of 7.3 μM.

EXTRACTIONmedicine.drug_classStereochemistrySesterterpenoidsBiochemistryAldehydeAnti-inflammatorySesterterpenesNitric oxidechemistry.chemical_compoundAnti-inflammatory activityEPONGESpongeDrug DiscoverymedicineOrganic chemistryIC50ACTIVITE ANTIINFLAMMATOIREchemistry.chemical_classificationTESTACTIVITE BIOLOGIQUEbiologyOrganic ChemistryINVERTEBRE AQUATIQUEbiology.organism_classificationTerpenoidSpongechemistrySUBSTANCE NATURELLEDerivative (chemistry)
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How alternative food networks work in a metropolitan area? An analysis of Solidarity Purchase Groups in Northern Italy

2019

AbstractOur paper focuses on Solidarity Purchase Group (SPG) participants located in a highly urbanized area, with the aim to investigate the main motivations underlining their participation in a SPG and provide a characterization of them. To this end, we carried out a survey of 795 participants involved in 125 SPGs in the metropolitan area of Milan (Italy). Taking advantage of a questionnaire with 39 questions, we run a factor analysis and a two-step cluster analysis to identify different profiles of SPG participants. Our results show that the system of values animating metropolitan SPG practitioners does not fully conform to that traditionally attributed to an alternative food network (AF…

Economics and EconometricsConsumers’ behaviorTwo-step cluster analysis0211 other engineering and technologieslcsh:TX341-64102 engineering and technology010501 environmental sciencesHighly urbanized areaP4601 natural sciencesP25Short supply chainUrbanizationConsumers' behaviorddc:330lcsh:Agricultural industriesLocal foodMarketing0105 earth and related environmental sciencesI15business.industrylcsh:HD9000-9495021107 urban & regional planningFood safetyQ56Agricultural and Biological Sciences (miscellaneous)Metropolitan areaQ13SolidarityWork (electrical)AgricultureFood productsSustainabilityBusinesslcsh:Nutrition. Foods and food supplyFood ScienceAgricultural and Food Economics
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Higher education in the fight against poverty from the capabilities approach: The case of Spain

2017

Abstract This article describes relative poverty in Spain in relation to the other States in the European Union, following the European indicator AROPE. The official data provided by the National Statistical Institute of Spain and by Eurostat, refer to the year 2014 (the last one for which definitive data are available is 2015). Given the relative poverty of Spanish population, the failure of conventional economic theories, which conceive social development as GDP growth, is clear, and it is argued in favour of the human capabilities approach as a more adequate option for development, from a theoretical-practical point of view, for the reduction and/or eradication of poverty, as well as the…

Economics and EconometricsEconomic growthHigher educationmedia_common.quotation_subjectI24I25Capabilities approachManagement of Technology and InnovationPolitical sciencelcsh:AZ20-999ddc:6500502 economics and businessmedia_common.cataloged_instanceHigher educationProposals against povertylcsh:Social sciences (General)Business and International ManagementEuropean unionPovertyCitizenshipmedia_commonMarketingPovertybusiness.industry05 social sciencesSocial change050301 educationlcsh:History of scholarship and learning. The humanitiesSustainabilitylcsh:H1-99Basic needsbusiness0503 educationSocial responsibilityRelative poverty Spain050203 business & managementJournal of Innovation & Knowledge
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Does one size fit all? The impact of cognitive skills on economic growth

2016

Les Documents de Travail de l'IREDU, n°2016-1; This paper tests for heterogeneous effects of cognitive skills on economic growth across countries. Using a new extended dataset on cognitive skills and controlling for potential endogeneity, we find that the magnitude of the effect is about 60 per cent higher for low-income countries compared to high-income countries, and it more than doubles when low TFP countries are compared to high TFP countries. There are also marked differences across geographic regions. Using data on the share of the population with advanced and minimum skill levels, our results also indicate that high-income countries should focus on increasing the number of high skill…

Economics and EconometricsJEL: N - Economic History/N.N3 - Labor and Consumers Demography Education Health Welfare Income Wealth Religion and Philanthropy/N.N3.N37 - Africa • Oceania[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationPopulationeducationGrowthDevelopmentHeterogeneity.Human capitalEducationBasic skillsJEL : H - Public Economics/H.H5 - National Government Expenditures and Related Policies0502 economics and businessDevelopment economicsJEL: O - Economic Development Innovation Technological Change and Growth/O.O1 - Economic DevelopmentEconomics[ SHS.ECO ] Humanities and Social Sciences/Economies and financesCognitive skillEndogeneity050207 economics[SHS.ECO] Humanities and Social Sciences/Economics and FinanceeducationTotal factor productivity050205 econometrics education.field_of_study05 social sciencesJEL : O - Economic Development Innovation Technological Change and Growth/O.O1 - Economic Development1. No povertyJEL : I - Health Education and Welfare/I.I2 - Education and Research Institutions/I.I2.I25 - Education and Economic DevelopmentJEL: H - Public Economics/H.H5 - National Government Expenditures and Related Policies[ SHS.EDU ] Humanities and Social Sciences/Education[SHS.ECO]Humanities and Social Sciences/Economics and FinanceJEL: I - Health Education and Welfare/I.I2 - Education and Research Institutions/I.I2.I25 - Education and Economic Development8. Economic growthAfricaGeographic regionsDemographic economicsHeterogeneityJEL : N - Economic History/N.N3 - Labor and Consumers Demography Education Health Welfare Income Wealth Religion and Philanthropy/N.N3.N37 - Africa • OceaniaCognitive Skills
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Proximal and distal antecedents of problematic information technology use in organizations

2021

PurposeExcessive use of work-related information technology (IT) devices can lead to major performance and well-being concerns for organizations. Extant research has provided evidence of the incidence of such problematic IT use in organizations. We extend the understanding of problematic IT use by examining its individual (proximal) and organizational (distal) antecedents.Design/methodology/approachDrawing from the self-worth theory and the concept of fear of being left behind, we address proximal antecedents that lead to problematic IT use. Drawing from the concept of autonomy paradox, we address distal antecedents of problematic IT use through a positive association with the two proximal …

Economics and EconometricsSociology and Political ScienceIT insecuritymedia_common.quotation_subjecttieto- ja viestintätekniikkatyöhyvinvointi512 Business and managementtietotekniikkaStructural equation modelingExtant taxonAssociation (psychology)media_commonbusiness.industryCommunicationFear of missing outInformation technology113 Computer and information sciencesLeft behindtyön kuormittavuusfear of missing outFacilitationproblematic IT usedistal antecedentsbusinessPsychologySocial psychologyproximal antecedentsAutonomy
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