Search results for "ICO"

showing 10 items of 30544 documents

Antimicrobial photodynamic therapy using diode laser activated indocyanine green as an adjunct in the treatment of chronic periodontitis: A randomize…

2016

Abstract Introduction Clinical studies have shown the usefulness of antimicrobial photodynamic therapy (aPDT) as an adjunctive in periodontal therapy. These studies did not utilize indocyanine green (ICG) as a recently introduced photosensitizer. The aim of this study was to perform a full-mouth double-blind randomized controlled clinical study to test the efficacy of adjunctive aPDT with ICG compared with scaling and root planing (SRP) alone in chronic periodontitis treatment. Materials and methods Fifty patients were selected for this study. All patients received SRP. Then, each patient was randomly assigned to either the test group (aPDT + SRP) or the control group (SRP). aPDT was perfor…

0301 basic medicineAdultIndocyanine GreenMale030103 biophysicsGingival and periodontal pocketmedicine.medical_treatmentBleeding on probingBiophysicsDentistryPhotodynamic therapyDermatologylaw.invention03 medical and health scienceschemistry.chemical_compound0302 clinical medicineScaling and root planingRandomized controlled triallawmedicineHumansPharmacology (medical)Photosensitizing Agentsbusiness.industryReproducibility of Results030206 dentistryMiddle AgedReference Standardsmedicine.diseaseChronic periodontitisOncologychemistryClinical attachment lossPhotochemotherapyChronic PeriodontitisFemalemedicine.symptomLasers SemiconductorbusinessIndocyanine greenPhotodiagnosis and photodynamic therapy
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Biomonitoring and evaluation of permethrin uptake in forestry workers using permethrin-treated tick-proof pants.

2014

We conducted a randomized case-control trial to analyze uptake of the insecticide/arcaricide permethrin in wearers of permethrin-impregnated and non-impregnated pants in German forestry. Eighty-two male workers were each equipped for a 16-week period with permethrin-treated (test group) or with non-treated work pants (control group). Pants with or without lining to protect against cuts, obtained from two different distributors, were worn in each group. Urinary permethrin metabolite levels were measured by GC-MS/MS before, during and after wearing of the pants. Permethrin uptake was calculated using additional questionnaire data. In the control group, metabolite levels in the range of enviro…

0301 basic medicineAdultMaleAcceptable daily intakeEpidemiologyTest groupPopulation010501 environmental sciencesToxicology01 natural sciences03 medical and health sciencesYoung AdultProtective ClothingGermanyOccupational Exposureparasitic diseasesBackground exposureBiomonitoringMedicineAnimalsHumanseducationPermethrin0105 earth and related environmental scienceseducation.field_of_studyTick Bitesbusiness.industryPublic Health Environmental and Occupational HealthForestryForestryMiddle AgedPollutionQuestionnaire dataMale workers030104 developmental biologyCase-Control StudiesbusinessBiomarkersPermethrinmedicine.drugEnvironmental MonitoringJournal of exposure scienceenvironmental epidemiology
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Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

2018

Skin affections after sulfur mustard (SM) exposure include erythema, blister formation and severe inflammation. An antidote or specific therapy does not exist. Anti-inflammatory compounds as well as substances counteracting SM-induced cell death are under investigation. In this study, we investigated the benzylisoquinoline alkaloide berberine (BER), a metabolite in plants like berberis vulgaris, which is used as herbal pharmaceutical in Asian countries, against SM toxicity using a well-established in vitro approach. Keratinocyte (HaCaT) mono-cultures (MoC) or HaCaT/THP-1 co-cultures (CoC) were challenged with 100, 200 or 300 mM SM for 1 h. Post-exposure, both MoC and CoC were treated with 1…

0301 basic medicineAdultMaleCell typeResearchInstitutes_Networks_Beacons/MICRAIn silicotaittovirheetGenome-wide association studyRetinal Pigment EpitheliumBiologyBlindnessPolymorphism Single NucleotideSensory disorders Donders Center for Medical Neuroscience [Radboudumc 12]ArticleRetinaWhite People03 medical and health sciencesHIGH-GRADE MYOPIA ; RETINAL-PIGMENT EPITHELIUM ; SEROTONIN PATHWAY GENES ; FORM-DEPRIVATION MYOPIA ; COMMON VARIANTS ; OCULAR GROWTH ; RETINITIS-PIGMENTOSA ; GENOTYPE IMPUTATION ; MISSENSE MUTATIONS ; DOPAMINE-RECEPTORSAsian Peoplerefractive errorsRetinitis pigmentosaGeneticsmedicineMyopiaJournal ArticleHumansGenetic Predisposition to Disease610 Medicine & healthRegulation of gene expressionRetinaRetinal pigment epitheliummedicine.diseaseRefractive Errors030104 developmental biologymedicine.anatomical_structureManchester Institute for Collaborative Research on AgeingGene Expression Regulationgenetic factorsEye disorderFemalesense organsgeneettiset tekijätNeuroscienceGenome-Wide Association StudySignal Transduction
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Microbial Activation of Wooden Vats Used for Traditional Cheese Production and Evolution of Neoformed Biofilms.

2016

ABSTRACT Three Lactococcus lactis subsp. cremoris strains were used to develop ad hoc biofilms on the surfaces of virgin wooden vats used for cheese production. Two vats (TZ) were tested under controlled conditions (pilot plant), and two vats (TA) were tested under uncontrolled conditions (industrial plant). In each plant, one vat (TA1 and TZ1) was used for the control, traditional production of PDO Vastedda della Valle del Belìce (Vastedda) cheese, and one (TA2 and TZ2) was used for experimental production performed after lactococcal biofilm activation and the daily addition of a natural whey starter culture (NWSC). Microbiological and scanning electron microscopy analyses showed differenc…

0301 basic medicineAdultMaleLactococcus030106 microbiologyBiologyBacterial Physiological PhenomenaLactic acid bacteria; traditional cheeseApplied Microbiology and Biotechnology03 medical and health sciencesSettore AGR/17 - Zootecnica Generale E Miglioramento Genetico0404 agricultural biotechnologyStartertraditional cheeseCheeseLactic acid bacteriaFood microbiologyAnimalsHumansFood scienceEcologyBacteriaLactococcus lactisBiofilm04 agricultural and veterinary sciencesBiodiversityMiddle Agedbiology.organism_classification040401 food scienceWoodLactococcus lactisLactic acid bacteriumMilkBiofilmsTasteFood MicrobiologyFemaleBacteriaFood ScienceBiotechnologyMesophileSettore AGR/16 - Microbiologia AgrariaApplied and environmental microbiology
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Effect of laser treatment on postural control parameters in patients with chronic nonspecific low back pain: a randomized placebo-controlled trial

2019

The management of nonspecific lumbar pain (NSLP) using laser irradiation remains controversial. A systematic review of recently published studies indicates that the effects of laser therapy are commonly assessed using only imperfect methods in terms of measurement error. The main objective of this study was to assess static postural stability using an objective tool in patients with chronic NSLP after laser irradiation at different doses and wavelengths. In total, 68 patients were included in the laser sessions and were randomly assigned into four groups: high-intensity laser therapy at 1064 nm and 60 J/cm2 for 10 min (HILT), sham (HILT placebo), low-level laser therapy at 785 nm and 8 J/cm…

0301 basic medicineAdultMaleMedicine (General)QH301-705.5PhysiologyImmunologyBiophysicsPlacebo-controlled studyOcean EngineeringPlaceboBiochemistrylaw.invention03 medical and health sciencesR5-9200302 clinical medicineLumbarRandomized controlled trialLaser therapylawPostural BalanceMedicineHumansLow back painBiology (General)General Pharmacology Toxicology and PharmaceuticsLead (electronics)Pain Measurementbusiness.industryPhysical therapy modalitiesGeneral NeuroscienceCell BiologyGeneral MedicineMiddle AgedLow back pain030104 developmental biologyTreatment Outcome030220 oncology & carcinogenesisAnesthesiaPostural balanceChronic DiseaseFemaleAnalysis of variancemedicine.symptombusinessResearch ArticleFollow-Up StudiesBrazilian Journal of Medical and Biological Research
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Valorization of indigenous dairy cattle breed through salami production

2016

The aim of the research was to produce salami manufactured with meat of three different commercial categories of bovine breed: cow on retirement, beef and young bull. A total of six experimental productions, at small-scale plant, were carried out with and without starter culture inoculums. The evolution of physico-chemical parameters in all trials followed the trend already registered for other fermented meat products. Several LAB species were found during process with different levels of species diversity and frequency of isolation among inoculated (mainly Pediococcus pentosaceus and Staphylococcus xylosus) and uninoculated (mainly Enterococcus devriesei, Lactobacillus curvatus and Lactoba…

0301 basic medicineAdultMaleSettore AGR/19 - Zootecnica SpecialeMeatCinisara breed; Lactic acid bacteria; Meat fermentation; Salami; Starter culture; Adult; Animals; Bacteria; Cattle; Female; Food Handling; Humans; Male; Meat; Meat Products; Breeding; Fermentation; Food Microbiology; Food ScienceFood Handling030106 microbiologySalamiBreedingSensory analysis03 medical and health sciencesSettore AGR/17 - Zootecnica Generale E Miglioramento GeneticoStarterLactic acid bacteriaAnimalsHumansFood scienceDairy cattleMeat ProductbiologyBacteriaInoculationMeat fermentationAnimal0402 animal and dairy scienceStaphylococcus xylosusfood and beveragesRipening04 agricultural and veterinary sciencesSettore AGR/15 - Scienze E Tecnologie Alimentaribiology.organism_classification040201 dairy & animal scienceBreedLactobacillus sakeiMeat ProductsStarter cultureFermentationFood MicrobiologyCattleFemaleCinisara breedHumanFood ScienceSettore AGR/16 - Microbiologia Agraria
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Temporal-spatial characteristics of phase-amplitude coupling in electrocorticogram for human temporal lobe epilepsy.

2017

Objective Neural activity of the epileptic human brain contains low- and high-frequency oscillations in different frequency bands, some of which have been used as reliable biomarkers of the epileptogenic brain areas. However, the relationship between the low- and high-frequency oscillations in different cortical areas during the period from pre-seizure to post-seizure has not been completely clarified. Methods We recorded electrocorticogram data from the temporal lobe and hippocampus of seven patients with temporal lobe epilepsy. The modulation index based on the Kullback-Leibler distance and the phase-amplitude coupling co-modulogram were adopted to quantify the coupling strength between t…

0301 basic medicineAdultMaleTime Factorsmodulation indexModulation indexHippocampuscross-frequency couplingta3112HippocampusLateralization of brain functionTemporal lobe03 medical and health sciencesEpilepsyYoung Adult0302 clinical medicinePhysiology (medical)medicineHumansta113Human braintemporal lobe epilepsyMiddle Agedmedicine.diseaseECoGBrain Wavesta3124Sensory SystemsTemporal LobeElectrodes ImplantedCoupling (electronics)030104 developmental biologymedicine.anatomical_structureNeurologyEpilepsy Temporal LobeFemaleNeurology (clinical)Epileptic seizureElectrocorticographymedicine.symptomfall-max patternPsychologyNeuroscience030217 neurology & neurosurgeryClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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Sperm DNA fragmentation: An early and reliable marker of air pollution.

2017

Environmental factors could have a key role in the continuous and remarkable decline of sperm quality observed in the last decades. This study compared the seminal parameters and sperm DFI in men living in areas with different levels of air pollution. Results demonstrate that both steel plants workers and patients living in a high polluted area show a mean percentage of sperm DNA fragmentation above 30%, highlighting a clear sperm damage. In this work, two different techniques were used to measure sperm DNA damage in patients’ groups, finding in both cases a high sperm DFI in patients living in polluted areas. We candidate sperm DNA fragmentation as a valuable early marker of the presence…

0301 basic medicineAdultMaleendocrine systemHealth Toxicology and MutagenesisAir pollutionDNA FragmentationBiologymedicine.disease_causeToxicologyAndrology03 medical and health sciences0302 clinical medicineAir PollutionmedicineHumansIn patientSettore BIO/06 - Anatomia Comparata E Citologiareproductive and urinary physiologySperm motilityTUNELPharmacologyAir Pollutants030219 obstetrics & reproductive medicineurogenital systemSperm dnaApoptosiGeneral MedicineEnvironmental exposureEnvironmental ExposureSpermSpermatozoaSCD030104 developmental biologyEnvironmental healthItalySteelSperm MotilityDNA fragmentationParticulate MatterReproductive capacityEnvironmental toxicology and pharmacology
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Incidence of Stent Thrombosis after Endovascular Treatment of Iliofemoral or Caval Veins in Patients with the Postthrombotic Syndrome.

2019

Abstract Background Patients with postthrombotic syndrome (PTS) treated with stents are at risk of stent thrombosis (ST). The incidence of ST in the presence and absence of anticoagulation therapy (AT) is unknown. Risk factors are not well understood. Patients and Methods From the prospective Swiss Venous Stent registry, we conducted a subgroup analysis of 136 consecutive patients with PTS. Incidence of ST was estimated from duplex ultrasound or venography, and reported for the time on and off AT. Baseline, procedural, and follow-up data were evaluated to identify factors associated with ST. Results Median follow-up was 20 (interquartile range [IQR] 9–40) months. AT was stopped in 43 (32%) …

0301 basic medicineAdultMalemedicine.medical_specialty2720 HematologyVenographySubgroup analysis610 Medicine & healthVena Cava Inferior030204 cardiovascular system & hematologyIliac VeinPostthrombotic Syndrome03 medical and health sciences0302 clinical medicineFibrinolytic AgentsInterquartile rangeRisk FactorsmedicineAlloysHumansCumulative incidenceRegistries610 Medicine & healthStrokemedicine.diagnostic_testbusiness.industryIncidence (epidemiology)10031 Clinic for AngiologyIncidenceHazard ratioEndovascular ProceduresAnticoagulantsThrombosisHematologyPhlebographyFemoral VeinMiddle Agedmedicine.diseaseConfidence intervalSurgery030104 developmental biologyTreatment OutcomeFemaleStentsbusinessSwitzerlandFollow-Up StudiesThrombosis and haemostasis
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Effect of gene-gene and gene-environment interactions associated with antituberculosis drug-induced hepatotoxicity.

2017

This study evaluated the association between environmental factors and genetic variations in enzymes that metabolize antituberculosis (anti-TB) drugs [arylamine N-acetyltransferase 2, cytochrome P450 2E1 (CYP2E1), glutathione S-transferase theta 1 (GSTT1), and glutathione S-transferase mu 1] with antituberculosis drug-induced hepatotoxicity (ATDH). We also investigated the potential gene-gene and gene-environment interactions as well as their association with ATDH development in a population of hospitalized TB patients from Buenos Aires.We investigated 364 TB patients who received anti-TB drugs. Physicians collected demographic and clinical data to identify environmental risk factors for AT…

0301 basic medicineAdultMalemedicine.medical_specialtyAntitubercular AgentsBiologyPharmacologyPolymorphism Single Nucleotide03 medical and health scienceschemistry.chemical_compoundYoung Adult0302 clinical medicineMolecular geneticsGenotypeGenetic variationGeneticsmedicineHumansGeneral Pharmacology Toxicology and PharmaceuticsAlleleMolecular BiologyGeneGenetics (clinical)chemistry.chemical_classificationEpistasis GeneticGlutathioneCYP2E1gene antitubercolosis drug drug cytochrome geneticsSettore BIO/18 - Genetica030104 developmental biologyEnzymechemistryLiver030220 oncology & carcinogenesisMolecular MedicineFemalePharmacogenetics and genomics
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