Search results for "ICT."

H2-M, a facilitator of MHC class II peptide loading, and its negative modulator H2-O are differentially expressed in response to proinflammatory cyto…

2000

H2-M is a major histocompatibility complex (MHC) class II-like molecule that catalyzes peptide binding to MHC class II molecules. Recently, the H2-O heterodimer, encoded by H2-Oa and H2-Ob in the MHC class II region, has been shown to be physically associated with H2-M in B cells and to downregulate H2-M function. Examination of H2-O expression in freshly isolated mouse organs revealed that H2-Oa- and H2-Ob-specific transcripts are present in both lymphoid and nonlymphoid tissues. To evaluate the gene regulation and functional impact of H2-O on antigen presentation, we examined the effects on MHCII, invariant chain (Ii), H2-M, and H2-O gene expression of interleukin (IL)-4, IL-10, and inter…

Multiple levels of MHC class I down-regulation by ras oncogenes.

1996

A number of tumours and oncogene transformed cells displayed reduced MHC class I surface expression which seemed to enable their escape from immune surveillance. To test whether oncogenic activation is directly involved in suppressing MHC class I expression, a model of inducible oncogene expression was chosen. Mouse fibroblasts transfected with different oncogenes expressed under the control of the dexamethasone-inducible MMTV promoter were analysed in the presence and absence of hormone for the mRNA and protein expression of MHC class I molecules as well as the respective oncogenes. Immunofluorescence analyses demonstrated an inverse association of MHC class I and oncogene expression after…

Endothelin: an endothelium-derived vasoactive peptide and its possible role in the pathogenesis of cerebral vasospasm

1991

The contractile response to endothelin has been examined in cerebral arteries from rats subjected to a prior subarachnoid haemorrhage (SAH) and compared with saline injected controls. Endothelin elicited strong concentration-dependent contraction of rat basilar artery segments. The response was slow in onset and long lasting. The endothelin-induced contraction was much stronger in the SAH compared to control animals. Our findings suggest a role of the peptide in the pathophysiology of cerebral vasospasm.

Predictability, chaos and coordination in bird vigilant behaviour

1999

Computerized prediction of perforating appendicitis in children.

1989

"Haters gonna hate": characterizing hater comments on YouTube thanks to impoliteness theories

2017

International audience; Previous studies have shown that comments on YouTube tend to show a “low degree of neutral stance” (Sindoni, 2014: 203). Comments are often either strongly positive or negative. Negative comments themselves commonly display all forms of aggressive and impolite behaviour (sarcasm, name-calling, hostility, ad personam attacks and a whole variety of other deliberate face-threatening acts). The epitome of this behaviour is the so-called “hater”, a commenter that deliberately posts abusive comments (“you suck”, “”Miranda sings is shit”, “fuck you Miranda sings”), generally unconnected to the content of the video and/or not constructive (see definitions in Lange: 2007). Ev…

Unequal rapidity correlators in the dilute limit of the JIMWLK evolution

2019

We study unequal rapidity correlators in the stochastic Langevin picture of Jalilian-Marian-Iancu-McLerran-Weigert-Leonidov-Kovner (JIMWLK) evolution in the color glass condensate effective field theory. We discuss a diagrammatic interpretation of the long-range con elators. By separately evolving the Wilson lines in the direct and complex conjugate amplitudes, we use the formalism to study two-particle production at large rapidity separations. We show that the evolution between the rapidities of the two produced particles can be expressed as a linear equation, even in the full nonlinear limit. We also show how the Langevin formalism for two-particle correlations reduces to a Balitsky-Fadin…

Le contentieux de la rupture abusive de relations d'affaires établies entre dans le champ d'application de la clause compromissoire stipulée dans le …

2012

International audience; (Civ. 1re, 8 juillet 2010, n° 09-67.013, D. 2010. 2884, obs. X. Delpech, note M. Audit et O. Cuperlier ; ibid. 2540, obs. Centre de droit de la concurrence Yves Serra ; ibid. 2933, obs. T. Clay ; Rev. crit. DIP 2010. 743, note D. Bureau et H. Muir Watt ; cette Revue 2011. 667, obs. P. Delebecque ; Rev. arb. 2010. 513, note R. Dupeyré)

Que reste-t-il de l'abus dans le non-renouvellement du contrat ?

2014

International audience

CONFLICT DYNAMICS IN HEALTHCARE SERVICES: AN EXPERIMENTAL STUDY USING THE SYSTEM DYNAMICS METHODOLOGY

Σκοπός Η μελέτη αυτή χρησιμοποιεί τη συστημική προσέγγιση για να διερευνήσει τη δυναμική της μάθησης και του αρνητικού συναισθήματος στις συγκρούσεις μεταξύ εργαζομένων στο χώρο της υγείας. Η δυναμική μας υπόθεση ήταν ότι η αλληλεπίδραση μεταξύ των επιπέδων σύγκρουσης, πληροφορίας/μάθησης και αρνητικών συναισθημάτων που συσσωρεύονται στο χώρο εργασίας ως παραπροϊόντα της σύγκρουσης προκαλούν ενδογενώς την διακύμανση (ταλαντώσεις) των επιπέδων σύγκρουσης. Υλικό-Μέθοδος Πραγματοποιήθηκε αρχικά μια συστηματική ανασκόπηση της βιβλιογραφίας και εντοπίσθηκαν 2 προβληματικά πρότυπα εξέλιξης των εργασιακών συγκρούσεων με την πάροδο του χρόνου (Group Disintegration, Groupthink) και ένα "επιθυμητό" π…