Search results for "INVESTIGATION"

showing 10 items of 366 documents

The consequences of regulation of desat1 expression for pheromone emission and detection in Drosophila melanogaster.

2010

AbstractSensory communication depends on the precise matching between the emission and the perception of sex- and species-specific signals; understanding both the coevolutionary process and the genes involved in both production and detection is a major challenge. desat1 determines both aspects of communication—a mutation in desat1 simultaneously alters both sex pheromone emission and perception in Drosophila melanogaster flies. We investigated whether the alteration of pheromonal perception is a consequence of the altered production of pheromones or if the two phenotypes are independently controlled by the same locus. Using several genetic tools, we were able to separately manipulate the tw…

Fatty Acid DesaturasesMaleTranscription Genetic[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionMESH : Animals Genetically ModifiedMESH : GenotypeMESH: GenotypeAnimals Genetically ModifiedSexual Behavior AnimalMESH : HydrocarbonsMESH: Reverse Transcriptase Polymerase Chain ReactionMESH : Drosophila melanogasterDrosophila ProteinsMESH: AnimalsMESH : FemaleMESH: Sexual Behavior AnimalSex AttractantsGeneticsMESH: Nursing AssessmentMESH : Craniocerebral TraumabiologyMESH : Gene Expression RegulationReverse Transcriptase Polymerase Chain ReactionMESH : Fatty Acid DesaturasesMESH : Reverse Transcriptase Polymerase Chain ReactionMESH: Fatty Acid DesaturasesMESH: Gene Expression RegulationPhenotypeMESH: Intracranial PressureMESH: Sex AttractantsDrosophila melanogasterSex pheromonePheromoneFemaleDrosophila melanogasterMESH : MutationMESH: MutationGenotypeMESH : ComaMESH: Drosophila ProteinsMESH : MaleMESH: Craniocerebral TraumaSensory systemLocus (genetics)InvestigationsMESH: Drosophila melanogasterMESH: Animals Genetically ModifiedMESH: HydrocarbonsMESH: Education Nursing ContinuingGeneticsMESH : Nursing AssessmentAnimalsMESH : Sexual Behavior AnimalGeneMESH: ComaTranscriptional activityMESH : Sex AttractantsMESH: HumansMESH: Transcription GeneticMESH : HumansMESH : Transcription Geneticbiology.organism_classificationMESH : Drosophila ProteinsMESH: MaleHydrocarbonsMESH : Intracranial PressureGene Expression RegulationMutationMESH : AnimalsMESH : Education Nursing ContinuingMESH: Female[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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Results of the 12th “Iter Mediterraneum” in Tunisia, 24 March - 4 April, 2014

2015

Are here presented the Results of the 12th “Iter Mediterraneum” in Tunisia, 24 March - 4 April, 2014. They include: The organization and logistics of the 12th OPTIMA Iter in Tunisia by Domina & al.; a bioclimatic and vegetation overview of the studied areas by Smaoui; the Checklist of the vascular plants collected by Greuter & Domina; a first Checklist of the Bryophytes collected by Campisi & al; a first Checklist of the lichens collected by Guttová & al.

Floristic investigation; OPTIMA; Mediterranean Area; North AfricaSettore BIO/02 - Botanica SistematicaSettore BIO/03 - Botanica Ambientale E ApplicataOPTIMAMediterranean AreaNorth AfricaFloristic investigation
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A New Systematic Series of Foil Sections with Parallel Sides

2020

Parallel-sided foil sections are used for centerboards and rudders in sailing dinghy classes and also for struts placed in a fluid flow. The objective of this work is to create a systematic series of parallel-sided sections to be used under different conditions, with an emphasis on the sailing dinghies 470, 420 and Optimist. The loss, and surprisingly the gain, in performance relative to 4-digit NACA sections are also investigated. A 2D Reynolds-averaged Navier&ndash

Flow (psychology)low Reynolds numberOcean EngineeringGeometry02 engineering and technology01 natural sciencesBézier curves010305 fluids & plasmascenterboardlcsh:Oceanographysymbols.namesakegamma transition criterionlcsh:VM1-989parallel-sided0103 physical sciencesFluid dynamicssailingTrailing edgeCADlcsh:GC1-1581Settore ING-IND/15 - Disegno E Metodi Dell'Ingegneria IndustrialeWater Science and TechnologyCivil and Structural EngineeringMathematicsBézier curveSeries (mathematics)Turbulencelcsh:Naval architecture. Shipbuilding. Marine engineeringReynolds numberRadiusRudder021001 nanoscience & nanotechnologyNACAsystematic investigationsymbols0210 nano-technologyJournal of Marine Science and Engineering
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Spectrophotometric determination of promethazine by flow injection analysis and oxidation by CeIV

1992

A flow injection analysis (FIA) procedure is proposed for the determination of promethazine. The sample solution is directly injected into the carrier-reagent stream which comprises a solution of ceric ions in a sulphuric acid medium. The absorbance at 514 nm from the red colour developed by the oxidation of promethazine is measured. Effects of foreign substances have been investigated and the procedure has been applied to the determination of promethazine in a pharmaceutical formulation (tablets).

Flow injection analysisChromatographymedicine.diagnostic_testChemistryClinical BiochemistryPromethazine HydrochloridePharmaceutical ScienceCeriumPharmaceutical formulationPromethazineDosage formAnalytical ChemistryPromethazineAbsorbanceInvestigation methodsSpectrophotometrySpectrophotometryFlow Injection AnalysisDrug DiscoverymedicineOxidation-ReductionSpectroscopymedicine.drugJournal of Pharmaceutical and Biomedical Analysis
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Multidisciplinary analysis on a marble bas-relief of unknown origin

2022

The purpose of this study is to demonstrate how a disciplinary approach is an excellent tool in the field of forensic investigations, capable of answering the questions posed by the institution and obtaining as different and as much information as possible on the findings analyzed, reconstructing the history of often decontextualized artifacts. In the present work, the results of the FTIR-ATR and SEM-EDX analyses performed on micro-fragments and powders taken from a marble bas-relief, seized by the Cosenza Carabinieri Unit for the Protection of Cultural Heritage and Anti-Counterfeiting (Calabria, Italy), are reported.

Forensic investigations marble cultural heritageSettore GEO/09 -Georis. Miner.e Appl.Mineral.-Petrogr. per l'Ambi.ed i B.Cult.
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Multi-scale theoretical investigation of molecular hydrogen adsorption over graphene: coronene as a case study

2014

The physisorption of molecular hydrogen onto coronene is studied using a multi-scale theoretical approach with Density Functional Theory (DFT) calculations and Molecular Dynamics (MD) simulations. We consider two different kinds of model conformation for the approach of hydrogen towards the coronene i.e., systematic and random. For the systematic attack of hydrogen over coronene, the resulting potential energy profiles from DFT analysis are further found to resemble the Morse potential, and even the highly flexible Murrell–Sorbie (M–S) potential. The resulting M–S fitting also shows a zero-point energy correction of ∼16–17%. On the other hand, the potential energies from the random approach…

General Chemical EngineeringThermodynamicsGeneral ChemistryInteraction energyCoronene7. Clean energyPotential energyCoroneneCoronene; Molecular hydrogen; Theoretical investigationschemistry.chemical_compoundMolecular dynamicssymbols.namesakeMolecular hydrogenCoupled clusterchemistryTheoretical investigationssymbolsDensity functional theoryAtomic physicsvan der Waals forceMorse potentialRSC Adv.
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The Conserved Foot Domain of RNA Pol II Associates with Proteins Involved in Transcriptional Initiation and/or Early Elongation

2011

RNA polymerase (pol) II establishes many protein-protein interactions with transcriptional regulators to coordinate different steps of transcription. Although some of these interactions have been well described, little is known about the existence of RNA pol II regions involved in contact with transcriptional regulators. We hypothesize that conserved regions on the surface of RNA pol II contact transcriptional regulators. We identified such an RNA pol II conserved region that includes the majority of the >foot> domain and identified interactions of this region with Mvp1, a protein required for sorting proteins to the vacuole, and Spo14, a phospholipase D. Deletion of MVP1 and SPO14 affects …

GeneticsGuanylyltransferaseChromatin ImmunoprecipitationSequence Homology Amino AcidTranscription GeneticMolecular Sequence DataRNA polymerase IISaccharomyces cerevisiaeInvestigationsBiologyReal-Time Polymerase Chain Reactionchemistry.chemical_compoundchemistryTranscription (biology)Capping enzymeRNA polymeraseGeneticsTranscriptional regulationbiology.proteinAmino Acid SequenceRNA Polymerase IITranscription factor II DGeneConserved SequenceGenetics
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Epistasis and the Adaptability of an RNA Virus

2005

Abstract We have explored the patterns of fitness recovery in the vesicular stomatitis RNA virus. We show that, in our experimental setting, reversions to the wild-type genotype were rare and fitness recovery was at least partially driven by compensatory mutations. We compared compensatory adaptation for genotypes carrying (1) mutations with varying deleterious fitness effects, (2) one or two deleterious mutations, and (3) pairs of mutations showing differences in the strength and sign of epistasis. In all cases, we found that the rate of fitness recovery and the proportion of reversions were positively affected by population size. Additionally, we observed that mutations with large fitness…

GeneticsPopulation DensityMutationAnalysis of VarianceGenotypeEpistasis and functional genomicsAdaptation BiologicalRNA virusEpistasis GeneticSequence Analysis DNAViral Plaque AssayBiologyInvestigationsbiology.organism_classificationmedicine.disease_causeVesicular stomatitis Indiana virusEvolution MolecularMutational meltdownGenotypeMutationGeneticsmedicineEpistasisMutation–selection balanceAdaptation
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Coseismic Damage at an Archaeological Site in Sicily, Italy: Evidence of Roman Age Earthquake Surface Faulting

2018

Archaeoseismology can provide a useful chronological tool for constraining earthquakes and documenting significant evidence that would otherwise be lost. In this paper, we report a case of surface faulting on ancient man-made structures belonging to the archaeological site of Santa Venera al Pozzo situated along the eastern flank of Mt. Etna volcano in eastern Sicily (southern Italy), which is affected by well-developed tectonic faults. Geological surveys highlight a set of fractures affecting the archaeological ruins, suggesting the occurrence of a capable fault zone across the area. An integrated geophysical survey was carried out in order to identify the main subsurface tectonic disconti…

Geophysical investigation Archaeoseismological analysis Surface faulting Santa Venera al Pozzo Etna volcano010504 meteorology & atmospheric sciences010502 geochemistry & geophysics01 natural sciencesArchaeologyTectonicsGeophysicsDiscontinuity (geotechnical engineering)Etna volcanoGeochemistry and PetrologySettore GEO/11 - Geofisica ApplicataSeismic refractionElectrical resistivity tomographyRoman ageGeology0105 earth and related environmental sciencesArchaeoseismology
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LONG-TERM STRUCTURAL DEFICIENCIES IN A MAT FOUNDATION ON CLAY SOIL

2013

A 3-story building with a mat foundation consisting of a slab on a grid of grade beams performed poorly on clay soil. Cracking of the slab became rogressively worse as a result of the incorrect esign and fluctuations in the groundwater pressure under the foundation. The cyclic presence and absence of water rusted the steel reinforcement, and the sulfates in the clay soil caused formation of ettringite in the concrete. Plastic hinges formed in the slab and settlements occurred, causing damage to the beams. The situation is still in progress and may lead to the collapse of the structure under normal service conditions. The geotechnical and structural investigations performed to survey and ass…

Geotechnical investigationMat foundation Concrete slab Progressive collapse Differential settlements Soil-water movement.Mat foundationcrackingFoundation (engineering)Progressive collapsesoil water movementBuilding and Constructionprogressive collapsegeotechnical investigationsCrackingSettore ICAR/09 - Tecnica Delle CostruzioniShallow foundationdifferential settlementsSoil waterSlabMat foundation concrete slab progressive collapse differential settlements soil water movement cracking geotechnical investigationsGeotechnical engineeringSafety Risk Reliability and Qualityconcrete slabGroundwaterGeologyCivil and Structural Engineering
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