Search results for "IOS"

showing 10 items of 8115 documents

Eutopic endometrium from women with endometriosis does not exhibit neurotrophic properties

2012

The role of neurotrophins in eutopic endometrium from endometriosis-patients was investigated in a prospective study using immunofluorescence-staining, Western blot and a neuronal growth assay. The nerve growth factor is expressed in primary endometrial cell culture from women with and without endometriosis. Western blot analysis of endometrial biopsies or uterine fluid from patients with and without endometriosis shows no difference in the neurotrophin expression. We could not find a difference between patients with and without endometriosis with regards to the neurite outgrowth of sensory ganglia when treated with conditioned cultured medium or uterine fluid. This result refutes the assum…

AdultPathologymedicine.medical_specialtyNeuriteBlotting WesternImmunologyEndometriosisEndometriosisFluorescent Antibody TechniqueNeuriteEndometrial innervationAndrologyYoung AdultEndometrial innervation; Endometriosis; Pelvic painPelvic painWestern blotNeurotrophic propertieNerve Growth FactorNeuritesmedicineHumansImmunology and AllergyEutopic endometriumEndometriosiProspective cohort studyUterine Diseasesbiologymedicine.diagnostic_testbusiness.industryPelvic painDysmenorrhoeaMiddle Agedmedicine.diseaseSettore MED/40 - Ginecologia E OstetriciaNerve growth factorNeurologyCulture Media Conditionedbiology.proteinUterine DiseaseFemaleNeurology (clinical)medicine.symptombusinessNeurotrophinHuman
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Abdominal Wall Endometriosis: Myofibroblasts as a Possible Evidence of Metaplasia: A Case Report

2016

In this study, we report about a patient with extra-uterine endometriosis (EM) in the abdominal wall muscle with evident metaplasia based on the abundant alpha smooth muscle actin (ASMA)-expressing myofibroblasts. Laparotomy excision of the abdominal wall EM was done following ultrasonographic evidence of a hypodense swelling in the right rectus abdominis, which was confirmed by MRI. Immunohistochemistry staining for ASMA and collagen I was done, with the results confirming that endometriotic stromal cells expressed both. Anterior abdominal wall endometriosis was suspected because of the patient's history of recurrent EM combined with the cyclic nature of symptoms. MRI is useful in determin…

AdultPathologymedicine.medical_specialtyStromal cellRectus abdominimedicine.medical_treatmentEndometriosisRectus AbdominisEndometriosisCollagen Type IAbdominal wall03 medical and health sciences0302 clinical medicineMetaplasiaLaparotomymedicineHumansEndometriosiMyofibroblastsActinMetaplasiaMyofibroblast030219 obstetrics & reproductive medicinemedicine.diagnostic_testbusiness.industryAbdominal WallObstetrics and GynecologyMagnetic resonance imagingAnatomymedicine.diseaseMagnetic Resonance ImagingActinsmedicine.anatomical_structureReproductive Medicine030220 oncology & carcinogenesisImmunohistochemistryFemalemedicine.symptombusinessMyofibroblastHumanGynecologic and Obstetric Investigation
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Renal endometriosis mimicking complicated cysts of kidney: report of two cases

2017

Endometriosis is a common gynecologic disorder characterized by ectopic endometrial tissue growth outside the uterine cavity. Although usually occurring in pelvic organs, endometrial lesions may involve urinary tract. Renal endometriosis is extremely rare and it has only occasionally been reported in the past. We report two cases of patients with renal cystic lesions, incidentally found at imaging techniques during oncologic follow-up for gastric sarcoma and melanoma, initially misinterpreted as complicated haemorrhagic cysts and then histologically characterized as renal localizations of extragenital endometriosis.

AdultPathologymedicine.medical_specialtyUrinary systemEndometriosisEndometriosis030218 nuclear medicine & medical imagingClinical PracticeDiagnosis DifferentialRenal endometriosis - Extragenital endometriosis - Kidney - Complicated renal cyst - Endometrioma - Shading sign03 medical and health sciences0302 clinical medicinemedicineHumansPelvic organKidney030219 obstetrics & reproductive medicinebusiness.industryMelanomaKidney Diseases Cysticmedicine.diseaseEctopic endometrial tissueSettore MED/18 - Chirurgia Generalemedicine.anatomical_structureFemaleKidney DiseasesSarcomaUterine cavitybusinessSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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The histology of brain tumors for 67 331 children and 671 085 adults diagnosed in 60 countries during 2000-2014: a global, population-based study (CO…

2021

Abstract Background Global variations in survival for brain tumors are very wide when all histological types are considered together. Appraisal of international differences should be informed by the distribution of histology, but little is known beyond Europe and North America. Methods The source for the analysis was the CONCORD database, a program of global surveillance of cancer survival trends, which includes the tumor records of individual patients from more than 300 population-based cancer registries. We considered all patients aged 0-99 years who were diagnosed with a primary brain tumor during 2000-2014, whether malignant or nonmalignant. We presented the histology distribution of th…

AdultPediatricsmedicine.medical_specialtyCancer Researchepidemiological studypopulation-based cancer registriesDatabases FactualPopulationepidemiological study; health care disparities; histology; International Classification of Diseases; population-based cancer registries; primary brain tumorSocio-culturalehealth care disparitiesCancer registration610 Medicine & healthAstrocytomahistology03 medical and health sciencesGlobal population0302 clinical medicineInternational Classification of Diseasesepidemiological study health care disparities histology International Classification of Diseases population-based cancer registries primary brain tumormedicineHumans1306 Cancer ResearchRegistrieseducationChildMedulloblastomaprimary brain tumoreducation.field_of_studybusiness.industryBrain NeoplasmsAstrocytomaCancerHistology10060 Epidemiology Biostatistics and Prevention Institute (EBPI)medicine.diseaseEurope2728 Neurology (clinical)Oncology030220 oncology & carcinogenesisPopulation study2730 OncologyNeurology (clinical)business030217 neurology & neurosurgery
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Autoimmune polyglanduläre Syndrome

2013

The autoimmune polyglandular syndrome (APS) is defined as the manifestation of at least two endocrine autoimmune diseases. In order to take the wide spectrum of components and the variations of the disease fully into account, APS is usually divided up into the rare juvenile type (APS I) and the more common adult type (APS II-IV). APS I is caused by a monogenetic mutation whereas APS II-IV has a multifactorial genesis with combination related subgroups. Early diagnosis, individual adjustment of therapy and screening of high risk patients in particular are regarded as clinically relevant. In addition to the patient's history, the diagnosis of APS encompasses serologic measurement of organ-spe…

AdultPediatricsmedicine.medical_specialtyEndometriosisPhysical examinationHashimoto DiseaseDiseaseDiagnosis DifferentialHypothyroidismPregnancyHumansMass ScreeningMedicineHashimoto DiseasePolyendocrinopathies AutoimmuneMass screeningAutoantibodiesmedicine.diagnostic_testbusiness.industryIncidence (epidemiology)AutoantibodyGeneral MedicineDiabetes GestationalFemaleDifferential diagnosisbusinessInfertility FemaleRare diseaseDMW - Deutsche Medizinische Wochenschrift
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[Fetal pseudohypoaldosteronism: rare cause of hydramnios].

2005

PHA is a rare cause of hydramnios, characterized by increased amniotic fluid levels of aldosterone and sodium. Two distinct genetic entities (PHA type I and PHA type II) are included. Both are stemmed by a target organ defect with diminished renal tubular responsiveness to aldosterone. The AA present a case in which pregnancy resulted in a preterm infant with severe hydramnios, metabolic acidosis, hyponatriemia, hyperkaliemia. Salt and fluid replacement significantly improved clinical and metabolic condition. However a growth deficiency (-2 SDS) persists at follow-up.

AdultPolyhydramniosFetal DiseasesPolyhydramnioCesarean SectionPregnancyPseudohypoaldosteronismInfant NewbornHumansFemalePrognosisGrowth DisordersInfant PrematureLa Pediatria medica e chirurgica : Medical and surgical pediatrics
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Long-term evaluation of quality of life and gastrointestinal well-being after segmental colo-rectal resection for deep infiltrating endometriosis (EN…

2019

Purposes: The primary objective is to assess the long-term quality of life (QoL) and gastrointestinal well-being in patients with endometriosis (DIE) who underwent segmental resection (SR), through specific questionnaires focused on endometriosis and specific gastrointestinal evaluation. The secondary objectives are represented by the evaluation of peri-operative and post-operative outcomes of the procedure. Methods: This observational cohort study ENDO-RESECT (ClinicalTrials.gov ID: NCT03824054) reports all clinical data about women who underwent SR for DIE between October 2005 and November 2017. In the part of the study dedicated to the QoL assessment, the questionnaires adopted were the …

AdultQuality of lifemedicine.medical_specialtyAbdominal painConstipationAdolescentGastrointestinal DiseasesEndometriosisEndometriosisSegmental colo-rectal resectionHospital Anxiety and Depression ScaleGastrointestinal symptomsCohort StudiesYoung AdultPostoperative ComplicationsQuality of lifePregnancySurveys and QuestionnairesInternal medicineGastrointestinal symptommedicineHumansDeep infiltrating endometriosis; Gastrointestinal symptoms; Intestinal endometriosis; Personalized medicine; Quality of life; Segmental colo-rectal resection; Adolescent; Adult; Cohort Studies; Colorectal Neoplasms; Endometriosis; Female; Gastrointestinal Diseases; Humans; Middle Aged; Postoperative Complications; Pregnancy; Quality of Life; Surveys and Questionnaires; Treatment Outcome; Young Adultbusiness.industryIntestinal endometriosiObstetrics and GynecologyGeneral MedicineMiddle Agedmedicine.diseasePersonalized medicineDeep infiltrating endometriosiTreatment OutcomeSettore MED/40 - GINECOLOGIA E OSTETRICIADeep infiltrating endometriosisDeep infiltrating endometriosis; Intestinal endometriosis; Segmental colo-rectal resection; Quality of life; Gastrointestinal symptoms; Personalized medicineDefecationFemaleIntestinal endometriosisSegmental resectionmedicine.symptomColorectal NeoplasmsbusinessCohort study
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Religious comfort and anxiety in women with cancer: The mediating role of hope and moderating role of religious struggle

2018

OBJECTIVE Religiosity is an important source of consolation among individuals suffering from cancer. However, religion does not always bring comfort. Religious struggles elicit stress. We examined whether religious comfort predicts anxiety in patients diagnosed as having cancer. Hope was examined as a mediator and religious struggle as a moderator in this relationship. METHODS In this cross-sectional, descriptive-analytical research, 77 Polish women with cancer were selected using sequential convenience sampling. Data were collected using the Religious Comfort and Strain Scale, the Adult Hope Scale, and the State-Trait Anxiety Inventory. A statistical procedure using Pearson's correlation c…

AdultReligion and PsychologyeducationExperimental and Cognitive PsychologyAnxietyConflict PsychologicalReligiosityHopeYoung Adult03 medical and health sciences0302 clinical medicineModerated mediationNeoplasmsmedicineHumansIn patientConsolation030212 general & internal medicineAgedMiddle AgedModerationPsychiatry and Mental healthCross-Sectional StudiesOncology030220 oncology & carcinogenesisScale (social sciences)GuiltAnxietyFemaleAdult Hope ScalePolandmedicine.symptomPsychologyClinical psychologyPsycho-Oncology
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Can Fear of COVID-19 Be Predicted by Religiosity and Trust in Institutions among Young Adults? A Prospective Cross-National Study.

2022

The aim of this study was to reveal whether religiosity and trust in institutions are longitudinal predictors of change in fear of COVID-19 (FCV-19) across Poland, Germany, Slovenia, and Israel among young adults over a three-month period. The representative sample consisted of 1723 participants between the ages of 20 and 40 years (M = 30.74, SD = 5.74) across Poland (n = 446), Germany (n = 418), Slovenia (n = 431), and Israel (n = 428). The first measurement was carried out in February 2020 and the second was conducted in May/June 2020. A repeated-measures, two-way, mixed-factor ANOVA was performed to examine changes over time (T) and across countries (C) as well as the interaction of time…

AdultReligionYoung AdultHealth Toxicology and MutagenesisPublic Health Environmental and Occupational HealthCOVID-19HumansFemalefear of COVID-19; religiosity; trust in institutions; young adults; a longitudinal study designFearProspective StudiesTrustInternational journal of environmental research and public health
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Acute abdomen due to endometriosis in a premenopausal woman taking tamoxifen.

2003

Tamoxifen exhibits agonistic properties on the uterus. We describe a premenopausal woman who, while having tamoxifen due to a diagnosis of in situ ductal carcinoma, developed endometriosis requiring surgery.

AdultSelective Estrogen Receptor Modulatorsmedicine.medical_specialtyAntineoplastic Agents HormonalEndometriosisUterusEndometriosisBreast NeoplasmsCarcinomamedicineHumansskin and connective tissue diseasesGynecologybusiness.industryCarcinoma Ductal BreastObstetrics and GynecologyDuctal carcinomamedicine.diseaseAntiestrogenAbdominal PainOvarian CystsTamoxifenmedicine.anatomical_structureReproductive MedicinePremenopauseAcute abdomenAcute DiseaseFemalemedicine.symptombusinesshormones hormone substitutes and hormone antagonistsTamoxifenmedicine.drugEuropean journal of obstetrics, gynecology, and reproductive biology
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