Search results for "Joint"
showing 10 items of 1472 documents
Spinal and supraspinal mechanisms affecting torque development at different joint angles
2015
INTRODUCTION We examined the neural mechanisms responsible for plantar flexion torque changes at different joint positions. METHODS Nine subjects performed maximal voluntary contractions (MVC) at 6 ankle-knee angle combinations [3 ankle angles (dorsiflexion, anatomic position, plantar flexion) and 2 knee angles (flexion, full extension)]. Neural mechanisms were determined by V-wave, H-reflex (at rest and during MVC), and electromyography during MVC (RMS), normalized to the muscle compound action potential (V/Msup, Hmax/Mmax, Hsup Msup and RMS/Msup) and voluntary activation (VA), while muscle function was assessed by doublet amplitude. RESULTS MVC and doublet amplitude were significantly low…
Self-reported flares are predictors of radiographic progression in rheumatoid arthritis patients in 28-joint disease activity score remission: a 24-m…
2016
Background Disease flares are common in rheumatoid arthritis (RA) and are related to structural damage. However, few data on the impact of flares reported by patients on radiographic progression are available. Our aim was to investigate whether overall flares (OF), self-reported flares (SRF) and short flares assessed at the visit (SF) predict radiographic progression in RA patients in DAS28 (28-joint disease activity score) remission. Methods We reviewed the records of RA patients included in our database. We considered all patients who had a period of at least 24 months in remission (DAS28 0. Patients were assessed every 3 months and flares were recorded. We defined SRF as any worsening of…
The arterial blood supply of the temporomandibular joint: an anatomical study and clinical implications
2013
Purpose: The aim of this study was to analyze three-dimensional images of the arterial supply to the temporomandibular joint. Materials and Methods: Ten patients (five men and five women, mean age 36 years) without signs or symptoms of temporomandibular disorders, who underwent contrast-enhanced computed tomographic (CT) scanning with intravenous contrast, were studied. The direct volume rendering technique of CT images was used, and a data set of images to visualize the vasculature of the human temporomandibular joint in three dimensions was created. After elaboration of the data through post-processing, the arterial supply of the temporomandibular joint was studied. Results: The analysis …
Is time to joint replacement a valid outcome measure in clinical trials of drugs for osteoarthritis?
2003
The rate of radiographic joint space narrowing is commonly used today as a structural outcome measure in clinical trials evaluating potential disease-modifying drugs in patients with hip osteoarthritis, but this results in a continuous variable. Among the methods proposed to circumvent this problem, it has been suggested that the incidence of total hip arthoplasty (THA) provides a hard outcome measure. It is a dichotomized variable, easy to measure and sensitive to change, with acceptable intrinsic validity. However, because this measure is limited by the variability of factors underlying the decision to perform surgery and the length of waiting lists, it has been suggested that time to ful…
Funktionsangiographie der kniegelenknahen Arterien: Konsequenzen für die Stentimplantation?
1990
Angiographic studies of the arteries adjoining the knee in 25 patients show extensive kinking and stenoses of the popliteal artery and less frequently of the distal femoral artery during flexion of the knee joint. This is due to the loss of elasticity with increasing age forcing the vessel into a tortuous course during shortening of the pathway of the popliteal artery with knee flexion. Independent of the principle of the different stents available they probably will not increase the contractility of the stented vessel in the longitudinal axis. It is to expect that after implantation of stents into the popliteal artery kinking will occur predominantly in the original segments of the vessel …
The effect of cement fixation on initial micromotion of the femoral component in condylar knee replacement
1992
Four fresh, cadaveric specimens were fitted with total knee replacements and mounted on a knee joint loading and measuring rig. Femoral component micromotion in the sagittal plane was measured with a transducer during flexion and extension of the specimen. Various condylar designs were used without and with cement. Movement followed a characteristic curve pattern and was less with cement fixation particularly for bone of low trabecular strength as determined by bone sample tests for stiffness. Cement fixation appears to be superior to cementless fixation.
AB1394 Compliance and arthralgias in clinical therapy (compact): Assessment of the incidence of arthralgia, therapy costs and compliance within the f…
2013
Background Aromatase inhibitors (AI) are well established as adjuvant endocrine treatment for postmenopausal women with hormone receptor-positive (HR+) early breast cancer (EBC). Drug-induced myalgia or arthralgia is among the most frequently reported adverse drug reactions to AIs. Objectives Little is known about the pathomechanism by which AIs cause muscle and joint injury. The literature on skeletal muscle complaints with AIs is confusing, in part because of a lack of clear definitions. Myalgia/arthralgia is defined as muscle/joint pain and is likely to affect patients’ quality of life and compliance with AI medication . We designed a prospective trial to collect real world data on the e…
Decreasing muscle performance associated with increasing disease activity in patients with rheumatoid arthritis
2018
Objectives Increasing evidence suggests that inflammation has a detrimental effect on muscle strength. Our objective was to analyse the association between muscle performance and different disease activity levels in patients with rheumatoid arthritis (RA). Method A total of 199 consecutive outpatients were subject to cross-sectional assessment. Measurements of grip strength, endurance of the upper and lower limbs and trunk strength were combined as a muscle performance composite score (MPCS), using a standardised method. The disease activity for 28 joints (DAS28), radiographs of small joints (Larsen score), rheumatoid factor, body mass index (BMI), comorbidities and anti-rheumatic drugs wer…
Saistība starp audzināšanas pieejām, vecāku un bērnu kopīgu spēlēšanos un sociālajām prasmēm 3-4 gadus veciem bērniem
2021
Pētījuma mērķis bija izpētīt saistību starp audzināšanas pieejām, vecāku un bērnu kopīgu spēlēšanos un sociālajām prasmēm 3-4 gadus veciem bērniem. Pētījuma jautājums - vai pastāv saistība starp audzināšanas pieejām, bērnu un vecāku kopīgu spēlēšanos un sociālām prasmēm 3 -4 gadus vecām meitenēm un zēniem? Pētījumā tika ievākti dati par 90 bērniem vecumā no 3 līdz 4 gadiem, no kuriem 41 bija meitene un 49 zēni, 42 bērni bija 3 gadus veci, 47 bērni bija 4 gadus veci, viens vecāks nebija norādījis bērna vecumu. Pētījuma aptaujas aizpildīja 86 mātes un 4 tēvi. Vecākiem tika lūgts elektroniski aizpildīt Vainlanda adaptīvās funkcionēšanas skalu Sociālo prasmju skalu (The Vineland Adaptive Behavi…