Search results for "LAB"
showing 10 items of 7932 documents
Naudas atmazgāšana būtība, shēmas un ietekme uz Eiropas ekonomiku
2022
Mūsdienu ekonomikas attīstību ietekmē daudzi faktori. Jebkurai valstij ir aktīvi jāpiedalās noziedzīgi iegūtu līdzekļu legalizācijas un terorisma finansēšanas novēršanā, lai saglabātu veselīgu ekonomisko vidi. Naudas atmazgāšana un terorisma finansēšana ir plaši atzītas par divām vissvarīgākajām pasaules mēroga problēmām, kas rada nopietnus draudus visām valstīm. Naudas atmazgāšana tiek veikta par labu tādām nelikumīgām darbībām kā terorismu, korupciju, narkotiku un cilvēku tirdzniecību. Oficiālā statistika neaptver visas ekonomiskās darbības, kas radušās naudas atmazgāšanas rezultātā, tādējādi kaitējot valstu ekonomikai kopumā. Bakalaura nosaukums ir naudas atmazgāšana būtība, shēmas un ie…
Safety and immunomodulatory effects of three probiotic strains isolated from the feces of breast-fed infants in healthy adults: SETOPROB study.
2013
We previously described the isolation and characterization of three probiotic strains from the feces of exclusively breast-fed newborn infants: Lactobacillus paracasei CNCM I-4034, Bifidobacterium breve CNCM I-4035 and Lactobacillus rhamnosus CNCM I-4036. These strains were shown to adhere to intestinal mucus in vitro, to be sensitive to antibiotics and to resist biliary salts and low pH. In the present study, a multicenter, randomized, double-blind, placebo-controlled trial with 100 healthy volunteers in three Spanish cities was carried out to evaluate the tolerance, safety, gut colonization and immunomodulatory effects of these three probiotics. Volunteers underwent a 15-day washout perio…
Método de medida de umbrales en direcciones oponentes
2019
El documento contiene un primer apartado con un organigrama explicativo, 2 apartados teóricos para comprender los espacios de color y como podemos utilizarlos, un tercero para explicar de manera muy básica como usar el programa de Demo_Estimuls para generar nuestros estímulos, y un quinto apartado donde queda agrupada la programación para Matlab. El documento describe de manera simplificada un metodo de medida de umbrales en las direcciones oponentes mediante un test con el método de escalera, incluyendo breves explicaciones sobre los espacios de color utilizados, y una explicación básica del uso del programa Demo_Estimuls de Matlab, además de la programación necesaria para la creación de e…
Partial substitution of fish meal with vegetable protein sources in a diet for sea bass: effects on lipogenesis
2005
Three isoproteic (49.4%) and isolipidic (17.0%) diets were prepared: A control diet FM, in which protein was derived from fish meal and two experimental diets in which 70% of the fish meal protein was substituted with wheat gluten meal (WGM) or wheat gluten meal plus soybean meal (WGMsb), respectively. The essential limiting amino acids were added to satisfy the requirements of the species (Tibaldi et al., 1996). Three hundred and fifteen sea bass (initial weight = 23.9±0. 1g )were randomly divided into nine homogenous groups. The animals were reared in a closed recirculation system at 23.9 ◦ C and were fed ad libitum twice a day for 96 days. The fish were weighed at the beginning and the e…
Elucidation of the biosynthesis and degradation of allantofuranone by isotopic labelling and fermentation of modified precursors.
2010
Feeding experiments with the ascomycete Allantophomopsis lycopodina indicated that the potent fungistatic allantofuranone is biosynthesized from phenylalanine. Further experiments with synthetic precursors gave evidence that the naturally occurring polyporic acid serves as a key intermediate in the biosynthesis. In addition to the formation of allantofuranone, its abiotic and metabolic degradation were investigated.
Improving Dissolution Behavior and Oral Absorption of Drugs with pH-Dependent Solubility Using pH Modifiers: A Physiologically Realistic Mass Transpo…
2021
Orally dosed drugs must dissolve in the gastrointestinal (GI) tract before being absorbed through the epithelial cell membrane. In vivo drug dissolution depends on the GI tract's physiological conditions such as pH, residence time, luminal buffers, intestinal motility, and transit and drug properties under fed and fasting conditions (Paixao, P. et al. Mol. Pharm. 2018 and Bermejo, et al. M. Mol. Pharm. 2018). The dissolution of an ionizable drug may benefit from manipulating in vivo variables such as the environmental pH using pH-modifying agents incorporated into the dosage form. A successful example is the use of such agents for dissolution enhancement of BCS class IIb (high-permeability,…
Bioaccessibility of calcium, iron and zinc from three legume samples
2004
Legumes can be a source of mineral elements but also of antinutritional factors which can affect their absorption. An in vitro method including gastrointestinal digestion was used to estimate mineral bioavailability. Soluble (bioaccessible) and insoluble calcium, iron and zinc from white beans, chickpeas and lentils were determined after gastrointestinal digestion. The influence of the original sample weight on the soluble mineral fraction was also estimated. The results obtained show that white beans are the legumes with the highest bioaccessible calcium and iron contents. Lentils have a high iron content but its bioaccessibility is much lower than that of iron from white beans and chickpe…
Development and Characterization of an Amorphous Solid Dispersion of Furosemide in the Form of a Sublingual Bioadhesive Film to Enhance Bioavailabili…
2017
Administered by an oral route, Furosemide (FUR), a diuretic used in several edematous states and hypertension, presents bioavailability problems, reported as a consequence of an erratic gastrointestinal absorption due to various existing polymorphic forms and low and pH-dependent solubility. A mucoadhesive sublingual fast-dissolving FUR based film has been developed and evaluated in order to optimize the bioavailability of FUR by increasing solubility and guaranteeing a good dissolution reproducibility. The Differential Scanning Calorimetry (DSC) analyses confirmed that the film prepared using the solvent casting method entrapped FUR in the amorphous state. As a solid dispersion, FUR increa…
Nākotnes perspektīvas suverēnās labklājības fondu darbībā Persijas Līča Sadarbības padomes reģionā
2015
Mana bakalaura darba tēma ir „Nākotnes perspektīvas suverēnās labklājības fondu darbībā Persijas Līča Sadarbības Padomes reģionā”. Mērķis ir izpētīt, suverēnās labklājības fondu attīstību nākotnē. Uzdevumi - starptautiskās finanšu sistēmas raksturojums, reģiona un turētājvalstu ekonomisko rādītāju, dokumentācijas un informācijas avotu analīze. Pētījums - trīs suverēnās labklājības fondu rādītāju analīze, stratēģiju noteikšana, darbības apjoma pieauguma radītāju analīze un secinājumu veidošana. Pētījuma rezultāti apstiprina, ka suverēnās labklājības fondi Persijas Līča Sadarbības padomes reģionā ir valstu alternatīva nākotnes paaudžu labklājības veidošanā.