Search results for "LENI"
showing 10 items of 756 documents
Cytoprotective organoselenium compounds for oligodendrocytes
2021
Abstract Herein we report the synthesis of peptide-like and tetrazole-based organoselenium compounds via Ugi and Ugi-azide reactions, respectively. The organoselenium compounds' intrinsic cytoprotective and antioxidant capacities were evaluated in 158 N and 158JP murine oligodendrocytes. Furthermore, their redox properties were theoretically evaluated using Molecular Operating Environment-docking studies. Most of the compounds did not exhibit any cytotoxicity against the 158JP and 158 N cells. Among the tested compounds, the tetrazole- (e.g., 6, 7, and 9) and the pseudopeptide-based organoselenium compounds (e.g., 11, 15, and 17) displayed antioxidant properties. On the other hand, the quin…
Antioxidant activity and fatty acids quantification in Sicilian purslane germplasm
2019
Portulaca oleracea is an annual succulent herb in the family Portulacaceae. It is a nutritious vegetable with high antioxidant properties and, it is among the richest plant source of ω-3 fatty acids, as well as a rich source of ω-6 fatty acids, ascorbic acid, tocopherols and beta-carotene. In the present study, three purslane populations under different Mediterranean environmental conditions for two years, for future valorization as novel food sources of omega-3 fatty acids, were evaluated. In particular, biomorphological characteristics, total phenols and fatty acids content were determined. The antioxidant activities were evaluated using 2,2-diphenyl-1-picrylhydrazyl assay. The population…
Chronic atrial fibrillation in presence of aortic stenosis in a patient with polysplenia syndrome.
2013
We report a rare case of “situs viscerum ambiguous” with polysplenia syndrome, in a 69 year old female patient with aortic stenosis and chronic atrial fibrillation. The presenting symptom was dyspnoea on moderate exertion and an ECG showed supra ventricular arrhythmia. Patients trans-thoracic echocardiogram revealed a dilated left atrium, reduced ejection fraction, mild tricuspid regurgitation, moderate-severe pulmonary hypertension and severe aortic stenosis. The patient was successfully treated with a replacement of her aortic valve and ascending aorta.
A no-carrier-added72Se/72As radionuclide generator based on solid phase extraction
2005
Summary72As-labelled radiopharmaceuticals could be a valuable resource for Positron Emission Tomography (PET). In particular, the long half-life of72As (T1/2= 26 h) facilitates the observation of long-term physiological or metabolic processes, such as the enrichment and distribution of antibodies in tumor tissue. This work describes the primary radiochemical separation of no-carrier-added (nca)72Se from cyclotron irradiated germanium targets and the development of a polystyrene type solid-phase extraction based72Se/72As radionuclide generator, avoiding the addition of any selenium carrier. The irradiated germanium target is dissolved in HFconcand selenium is reduced with hydrazine dihydroch…
Selinunte (Sicily) and its productive context: the clayey raw materials applied in a long-lived ceramic production (seventh to third century BCE)
2016
The westernmost of the Greek-Sicilian towns, Selinunte, founded in western Sicily during the second half of the seventh century BCE, gives amazing evidences of a historic activity of ceramic production (seventh to third century BCE). The present study aims to identify the raw materials available in the vicinity of the archaeological site of Selinunte, which were possibly used by the ancient potters, and to characterise them by means of petrographic and chemical techniques. A sampling campaign of clays and sands for tempering was undertaken in the archaeological site and the adjacent area. Moreover, locally produced archaeological bricks and tiles were considered helpful for comparison regar…
Last Glacial Human Settlement in Eastern Cantabria (Northern Spain)
2002
While the excavation of individual sites remains fundamental to the creation of the Palaeolithic archeological record, increasingly the focus of prehistoric research is on human adaptations to and within natural regions. Such a reorientation implies viewing sites and occupations as samples of different suites of activities in various habitats across space and time; it is dependent on the use of radiocarbon to date and relate occupation residues among sites; and it necessitates the application of methods to uncover patterns of human mobility as an integral aspect of subsistence economy, demographic arrangements and social relations. This paper contributes to the regional study of Last Glacia…
The public and private use of space in Magdalenian societies: Evidence from Oelknitz 3, LOP (Thuringia, Germany)
2015
Abstract The site of Oelknitz (Thuringia, Germany) is among the largest and in terms of spatial organisation most complex Magdalenian open air sites known to date, rich in evident structures. The current paper reports evidence from the youngest, latest phase of occupation at Oelknitz Structure 3. It is demonstrated that this structure represents a dwelling construction characterised by different spatially distinct activity zones. Several hypotheses can be drawn from this evidence in order to understand basic principles on Magdalenians’ settlement behaviour and their social cohesion.
Sobre cerámicas Helenísticas en Iberia / Hispania. Significado y funcionalidad
2012
In this work we are going to take a chronological and typological tour by studying the iconography that appears in the Hellenistic wares imported from the Central and Oriental Mediterranean between 3rd and 2nd centuries BC in Hispania Citerior, in particular from Cartagena. We are going to analyze its functionality in the places of origin, and with the help of the Hispanic contexts we will conclude whether its presence here is a consequence of a certain commercial dynamic, or if it answers to a decorative preference, of taste or trend; even if the images are significant related to ritual or convivial uses, public or private, by the local inhabitant who acquires and uses them.
Materiales del Paleolítico Superior en Cova Negra (Xàtiva) y su interés para establecer los procesos de su secuencia estratigráfica
2017
En este trabajo se analizan los materiales líticos adscritos al Paleolítico Superior obtenidos en Cova Negra a lo largo de las campañas de excavación de los años 30, 50 y 80 del pasado siglo y en las campañas de 2013-2016. La atención se centra en el estudio de los soportes, los núcleos y el material retocado, y se efectúa una primera aproximación con respecto a la cronología y periodos a los que remiten las piezas retocadas. El principal interés de estos materiales reside en confirmar que la ocupación de la cavidad no se limitó al Paleolítico Medio, ni a momentos iniciales de la secuencia del Paleolítico Superior, lo que facilita una evaluación del alcance de los procesos de alteración pos…
Ceramic production at Selinunte (Sicily) during the 4th and 3rd century BCE: New archaeometric data through the analysis of kiln wastes
2018
Abstract A set of 37 overfired ceramic samples was collected from the dump of two kilns sited in the productive area FF1 in the acropolis of Selinunte (south western Sicily), being specifically active in the period 409–250 BCE. The ceramic samples were analysed by thin-section petrography and chemical analysis, with the aim to establish a valuable ‘reference group’ representative of the ceramic produced at Selinunte during the Punic phase. The petrographic and chemical analyses allowed to state that the ceramic manufactures from the kilns operating in the FF1 insula are characterized by rather homogeneous textural/compositional features. The daily-use common ware here produced is characteri…