Search results for "Label"

Application of graph grammars in music composing systems

1987

Synthesis, X-ray Structure Determination, and Comprehensive Photochemical Characterization of (Trifluoromethyl)diazirine-Containing TRPML1 Ligands

2021

Potential (trifluoromethyl)diazirine-based TRPML1 ion channel ligands were designed and synthesized, and their structures were determined by single-crystal X-ray diffraction analysis. Photoactivation studies via 19F NMR spectroscopy and HPLC-MS analysis revealed distinct kinetical characteristics in selected solvents and favorable photochemical properties in an aqueous buffer. These photoactivatable TRPML activators represent useful and valuable tools for TRPML photoaffinity labeling combined with mass spectrometry.

The relation between tumor cell proliferation and vascularization in differentiated and undifferentiated colon carcinomas in the rat.

1982

Tumor cell proliferation and tumor vascularization were investigated in differentiated and undifferentiated colon carcinomas of the rat. The following results were found: 1, in both tumor types, vascularization is developed equally well; 2, both in the differentiated and in the undifferentiated carcinomas, the number of proliferating tumor cells decreases with increasing distance from the capillaries; at a distance of about 80 microns, there is no longer any noteworthy tumor cell proliferation; 3, the differentiated and undifferentiated carcinomas differ both in the level of the mitosis index and 3H-thymidine labeling index as well as in their local proliferation pattern despite equal vascu…

An Analysis of “No Effect of Insulin Pen with Memory Function on Glycemic Control in a Patient Cohort with Poorly Controlled Type 1 Diabetes: A Rando…

2012

Missing meal bolus and nonadherence is an important barrier to achieving glycemic goals in type 1 diabetes (T1DM). In this issue of Journal of Diabetes Science and Technology, Danne and coauthors reported the results of a 24-week randomized-controlled study designed to evaluate if using an insulin pen with memory function, the HumaPen® Memoir™, might improve injection compliance and, therefore, overall glycemic control in T1DM. Patients treated with the pen device with memory function improved, albeit nonsignificantly, their mean HbA1c by 0.43%. Among the reasons to justify why this study was not positive, the most important is the high proportion of adult patients included in the study (87…

“Zaļās” un ilgtspējīgās pasaules uztveres koncepcija biznesa vides tekstos

2019

Pēdējo gadu laikā cilvēki arvien vairāk sāk pievērst uzmanību apkārtējās vides draudiem un sāk vairāk apspriest ilgtspējību un “zaļās” domāšanas tematus. Patērētāji izdara spiedienu uz industrijām, izvēloties atbalstīt ilgspējīgi domājošus uzņēmumus un pērkot “zaļās” preces, tādēļ šī pētījuma mērķis ir noskaidrot vissatbilstošāko vārdšķiru kosmētikas produktu aprakstos un saprast kurš uzņēmums atspoguļo “zaļo” domāšanu visvairāk. Literatūras apskats sniedz teorētisko pamatu empīriskās daļas veikšanai. Kosmētikas aprakstu izpētes gaitā tika secināts, ka no vārdiem, kuri ir saistīti ar ilgtspējību, visbiežāk izmantotā vārdšķira ir īpašības vārds, kā arī tika secināts, ka pastāv saikne starp E…

Immunoelectron Microscopy of Vesicle Transport to the Primary Cilium of Photoreceptor Cells

2009

Cilia are organelles of high structural complexity. Since the biosynthetic machinery is absent from cilia all their molecular components must be synthesized in organelles of the cytoplasm and subsequently transported to the cilium. Ciliary cargos are thought to be translocated in the membrane of transport vesicles or association with these vesicles to the base of the cilium where the vesicles fuse with the periciliary target membrane for further delivery of their cargo into the ciliary compartment by the intraflagellar transport (IFT). Here we describe a modified preembedding labeling method as an alternative technique to conventional postembedding methods eligible for analyses of ciliary c…

What to show on the wine labels: a hedonic analysis of price drivers of Sicilian wines

2013

Unlike previous literature, we construct a hedonic model of wine price that incorporates all the main categories of variables simultaneously to enable a better evaluation of their importance on wine price formation. A comprehensive model has the advantage of providing more reliable estimates of the attributes' implicit prices thereby facilitating firms' pricing and improving effectiveness of wine production and marketing decisions. We utilize two different datasets of Sicilian wines collecting data from influential wine guides. Our results suggest that wine price strongly depends on objective features such as vintage, alcoholic content, geographical origin, grape variety, producer size and …

Electrospun Poly(ethylene-co-vinyl alcohol)/Graphene Nanoplatelets Composites of Interest in Intelligent Food Packaging Applications

2018

Graphene nanoplatelets (GNPs) were synthetized from graphite powder and, thereafter, embedded in poly(ethylene-co-vinyl alcohol) (EVOH) fibers by electrospinning in the 0.1&ndash

ChemInform Abstract: Synthesis of New Asymmetric Xanthene Dyes via Catalyst-Free SNAr with Sulfur Nucleophiles.

2014

Addition of a single functional handle to the tricyclic moiety of fluorescein results in asymmetric xanthene dyes. Our synthesis of a new class of asymmetric xanthenes proceeds via an unusual SNAr with sulfur nucleophiles on electron rich aromatic xanthenes scaffolds in the absence of a metal catalyst. The resulting 3′-thioethers exhibit high photostability and are conveniently converted into reactive dyes for macromolecule labelling.

Adaptive Learning Process for the Evolution of Ontology-Described Classification Model in Big Data Context

2016

International audience; One of the biggest challenges in Big Data is to exploit value from large volumes of variable and changing data. For this, one must focus on analyzing the data in these Big Data sources and classify the data items according to a domain model (e.g. an ontology). To automatically classify unstructured text documents according to an ontology, a hierarchical multi-label classification process called Semantic HMC was proposed. This process uses ontologies to describe the classification model. To prevent cold start and user overload, the classification process automatically learns the ontology-described classification model from a very large set of unstructured text documen…