Search results for "Laboratory"

showing 10 items of 923 documents

Hemoglobin point-of-care testing: the HemoCue system.

2013

Besides the use of traditional laboratory resources, the diagnosis of anemia can also be accomplished by assessing hemoglobin (Hb) concentration with point-of-care testing (POCT) devices such as the HemoCue test systems. In several situations, these devices might suitably replace traditional laboratory testing, including several areas of health care where a very rapid Hb measurement might be required to make immediate therapeutic decisions. The use of these devices, however, should fulfill some basic criteria, including economic, clinical, and regulatory issues; appropriate training of the users and knowledge of test requirements, performance, limitations, and potential interferences; the u…

business.industryComputer scienceQuality assessmentPoint-of-care testingPoint-of-Care SystemsAnemiahemoglobinLaboratory testinganemia; hemoglobin; point-of-care testingComputer Science ApplicationsTest (assessment)Medical Laboratory Technologypoint-of-care testingHemoglobinsRisk analysis (engineering)Equipment and SuppliesHealth careAnimalsHumansTest requirementsbusinessDelivery of Health CareSoftwareBiomedical engineeringJournal of laboratory automation
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Why Real Leisure Really Matters: Incentive Effects on Real Effort in the Laboratory

2013

On-the-job leisure is a pervasive feature of the modern workplace. We studied its impact on work performance in a laboratory experiment by either allowing or restricting Internet access. We used a 2×2 experimental design in which subjects completing real-effort work tasks could earn cash according to either individual- or team-production incentive schemes. Under team pay, production levels were significantly lower when Internet browsing was available than when it was not. Under individual pay, however, no differences in production levels were observed between the treatment in which Internet was available and the treatment in which it was not. In line with standard incentive theory, individu…

business.product_categorybusiness.industrymedia_common.quotation_subjectWork performanceIncentiveWork (electrical)CashInternet accessProduction (economics)The InternetMarketingLaboratory experimentbusinessmedia_commonSSRN Electronic Journal
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Sepsis in head and neck cancer patients treated with chemotherapy and radiation: literature review and consensus

2015

Abstract: The reporting of infection/sepsis in chemo/radiation-treated head and neck cancer patients is sparse and the problem is underestimated. A multidisciplinary group of head and neck cancer specialists from Italy met with the aim of reaching a consensus on a clinical definition and management of infections and sepsis. The Delphi appropriateness method was used for this consensus. External expert reviewers then evaluated the conclusions carefully according to their area of expertise. The paper contains seven clusters of statements about the clinical definition and management of infections and sepsis in head and neck cancer patients, which had a consensus. Furthermore, it offers a revie…

cancer patientpathogenesipositron emission tomographyhealthcare associated infectionSettore MED/06 - Oncologia Medicapatient monitoringradiodiagnosimedicine.medical_treatmentChemotherapy; Head and neck cancer; Radiotherapy; SepsisthrombocytopeniaReviewblood cultureorgan injurymedical terminologyMedicineHead and neck cancermetabolic acidosiC reactive proteinHead and Neck Neoplasmmedical specialisttreatment withdrawalconsensus developmentHematologyclinical practicesystemic inflammatory response syndromeItalyOncologyHead and Neck Neoplasmslaboratory testthrombocytosichemically induced/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingchemotherapy; head and neck cancer; radiotherapy; sepsis; oncology; hematology; geriatrics and gerontologyorgan perfusionhospitalizationHumansepsis Head and Neck Neoplasmmedicine.medical_specialtySettore MED/17 - Malattie InfettiveSepsibacterium culturediagnostic approach routefluorodeoxyglucosecancer chemotherapySepsisSDG 3 - Good Health and Well-beingSepsiscancer radiotherapyfollow upChemotherapyHumansinfection riskIntensive care medicineprocalcitonin antimicrobial therapyChemotherapyRadiotherapybusiness.industrydisease predispositionHead and neck cancerlactic acidChemotherapy; Head and neck cancer; Radiotherapy; Sepsis; Humans; Italy; Head and Neck Neoplasms; Sepsis; Hematology; Oncology; Geriatrics and Gerontologymedicine.diseasemortalityDelphi studyRadiation therapyinflammationincidencehyperglycemiaHuman medicineGeriatrics and Gerontologybusiness
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Biochemistry and cell biology of silica formation in sponges

2003

The main inorganic material forming the skeletal elements in Demospongiae as well as in Hexactinellida, the spicules, is amorphous silica. The spicules occur in the cytoplasm and the extracellular space and also in the nucleus (as silicate crystals) of some sponge cells; the function in the latter compartment is unknown. Recent evidence shows that the formation of spicules is mediated by the enzyme silicatein. The cDNA as well as the gene encoding this enzyme was cloned from Suberites domuncula. The recombinant silicatein catalyzes the syn- thesis of amorphous silicate using tetraethoxysilane as substrate. The enzyme is dependent on ferric iron. Silicatein also has proteolytic (cathepsin-li…

chemistry.chemical_classificationHistologyBiologybiology.organism_classificationSilicateCell biologySuberites domunculaMedical Laboratory Technologychemistry.chemical_compoundSpongeSponge spiculeEnzymechemistryBiochemistryCytoplasmGene expressionExtracellularAnatomyInstrumentationMicroscopy Research and Technique
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Cytochemical techniques for zinc and heavy metals localization in nerve cells

2002

Zinc is one of the most abundant oligoelements in the living cell. It appears tightly bound to metallothioneins, loosely bound to some metalloproteins and nucleic acids, or even as free ion. Small amounts of zinc ions (in the nanomolar range) regulate a plentitude of enzymatic proteins, receptors, and transcription factors; thus, cells need accurate homeostasis of zinc ions. Some neurons have developed mechanisms to accumulate zinc in specific membrane compartments ("vesicular zinc") which can be revealed using histochemical techniques. This article is a short report on the different direct-indirect experimental approaches for zinc and heavy metal detection in neurons. Substances giving a b…

chemistry.chemical_classificationHistologyChemistryPrecipitation (chemistry)Metal ions in aqueous solutionchemistry.chemical_elementSalt (chemistry)ZincMetalMedical Laboratory TechnologyMembraneBiochemistryvisual_artNucleic acidMetalloproteinvisual_art.visual_art_mediumAnatomyInstrumentationMicroscopy Research and Technique
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Der cytochemische Nachweis von Prolin-Dehydrogenasen, Acetaldehyd-Dehydrogenasen und Dihydrolipons�ure-Dehydrogenase in den Zellen vonSaccharomyces c…

1967

Using the tetrazolium salt Nitro-BT, the following dehydrogenases can be demonstrated cytochemically in the cells ofSaccharomyces cerevisiae: (1)Proline dehydrogenase activity: it cannot be decided whether the formazan production is a result of L-proline: NAD(P)-2-oxidoreductase (E.C. 1.5.1.1) or of L-proline:NAD(P)-5-oxidoreductase(E.C. 1.5.1.2); (2)Aldehyde dehydrogenase activity: using the coenzymes NAD and NADP and the activators KCl and MgCl2, different reaction pictures are obtained which led to the conclusion that aldehyde: NADP oxidoreductase (E.C. 1.2.1.4) and aldehyde: NAD(P) oxidoreductase (E.C. 1.2.1 5) can be demonstrated seperately; (3)Dihydrolipoic dehydrogenase (E.C. 1.6.4.3…

chemistry.chemical_classificationHistologybiologyChemistryAldehyde dehydrogenaseDehydrogenaseCell BiologyMolecular biologyCofactorMedical Laboratory Technologychemistry.chemical_compoundEnzymeBiochemistryOxidoreductasebiology.proteinProline dehydrogenase activityNAD+ kinaseFormazanMolecular BiologyHistochemie
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In vivo analysis of noise dependent activation of white blood cells and microvascular dysfunction in mice

2021

This article contains supporting information on data collection for the research article entitled “Aircraft noise exposure drives the activation of white blood cells and induces microvascular dysfunction in mice” by Eckrich et al. We found that noise-induced stress triggered microvascular dysfunction via involvement of innate immune-derived reactive oxygen species. In this article, we present the instrumentation of mice with dorsal skinfold chambers for in vivo microscopic imaging of blood flow, interaction of leukocytes with the vascular wall (also by fluorescent labelling of blood cells) and vessel diameter. In addition, we explain the preparation of cerebral arterioles for measurement of…

chemistry.chemical_classificationReactive oxygen speciesPathologymedicine.medical_specialtyScienceQClinical BiochemistryIn vivo analysisVideo microscopyBlood flowMethod ArticleIn vivo fluorescence microscopy and cerebral arteriole cannulation to assess noise induced changes in activation of white blood cells and microvascular dysfunctionIn vitroCerebral arterioles cannulationMedical Laboratory TechnologyDorsal skinfold chamberchemistryIn vivoFluorescent labeling of blood cellsVideo microscopyMicroscopic imagingmedicineResearch articleMethodsX
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Die acidolytische depolymerisation von trioxan in stationärer phase. 21. Mitt. über polyoxymethylene1

1964

Die Depolymerisation von Trioxan mit verschiedenen Phosphorsauren wurde im Temperaturbereich von 100–160°C untersucht. Sie fuhrt zu einem temperaturabhangigen Gleichgewicht zwischen Trioxan und Formaldehyd, das oberhalb 180°C weitgehend auf der Seite des Formaldehyds liegt. Zu einer schnellen Einstellung des Gleichgewichtes eignen sich Ortho- und Pyrophosphorsaure. Die bevorzugte Nebenreaktion ist die Bildung von Methylformiat; die Ausbeute an Methylformiat wird durch Erhohung der Reaktionszeit und der Katalysatoroberflache vergrosert. Das geschilderte Verfahren eignet sich zur Darstellung von monomerem Formaldehyd (Reinheitsgrad etwa 99,8%) im Laboratorium. Depolymerization of trioxane by …

chemistry.chemical_compoundLaboratory methodsMonomerchemistryTrioxaneDepolymerizationMethyl formatePolymer chemistryFormaldehydeSide reactionCatalysisDie Makromolekulare Chemie
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ChemInform Abstract: Elemental Bromine Production by TiO2Photocatalysis and/or Ozonation.

2016

Significant production of elemental bromine (Br2 ) was observed for the first time when treating bromide containing solutions at acidic pH, with TiO2 photocatalyst, ozone, or a combination thereof. Br2 selectivities up to approximately 85 % were obtained and the corresponding bromine mass balance values satisfied. The process is general and may be applied at a laboratory scale for green bromination reactions, or industrially as a cheap, safe, and environmentally sustainable alternative to the currently applied bromine production methods.

chemistry.chemical_compoundOzoneBrominechemistryBromideInorganic chemistryPhotocatalysisHalogenationchemistry.chemical_elementTio2 photocatalystGeneral MedicineLaboratory scaleChemInform
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Occurrence of mycotoxins in laboratory rat feeds

2015

chemistry.chemical_compoundchemistryGeneral MedicineFood scienceBiologyToxicologyMycotoxinLaboratory ratToxicology Letters
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