Search results for "Lung"

Taurine and the Lung

2003

Taurine (TAU) is the most abundant free amino acid in many tissues and in particular in proinflammatory cells like polymorphonuclear leukocytes and tissues exposed to elevated levels of oxidants1. Furthermore, orally administered TAU has been reported to reduce lung oxidant damage from exposure to ozone, nitrogen dioxide, paraquat, amiodarone and bleomycin in animal models2–5.

Novel Lymphocyte-Independent Antitumor Activity by PD-1 Blocking Antibody against PD-1+ Chemoresistant Lung Cancer Cells

2022

Abstract Purpose: Antibodies against the lymphocyte PD-1 (aPD-1) receptor are cornerstone agents for advanced non–small cell lung cancer (NSCLC), based on their ability to restore the exhausted antitumor immune response. Our study reports a novel, lymphocyte-independent, therapeutic activity of aPD-1 against NSCLC, blocking the tumor-intrinsic PD-1 receptors on chemoresistant cells. Experimental Design: PD-1 in NSCLC cells was explored in vitro at baseline, including stem-like pneumospheres, and following treatment with cisplatin both at transcriptional and protein levels. PD-1 signaling and RNA sequencing were assessed. The lymphocyte-independent antitumor activity of aPD-1 was explored in…

Lung Function Testing in Preschool Children

2017

TYPO-CHRONOLOGIE DES CÉRAMIQUES DU GROUPE RHIN-SUISSE-France -ORIENTALE (R.S.F.O.) DANS LA RÉGION DIJONNAISE :

2009

The archaeological site of the Pré-du-Plancher is located to the east of Dijon (Burgundy, Côte-d’Or), at the footof a limestone hill in the Basmont valley. This site, dated from the late Bronze Age, is the first to include a stratigraphicalsequence for this period in Burgundy. The settlement comprises of three buildings and several dumps containing potteryfinds. The study of the pottery as well as the site’s stratigraphy clearly identifies three chronological periods dating from Late Bronze Age IIb to Late Bronze age IIIa (French chronology) or Hallstatt A2 / B1 (German/Swiss chronology). Culturally, the site belongs to the Rhin-Suisse-France-Orientale group, the first phase showing influen…

First analysis of the National Lung Cancer Register in Spain (RTT).

2018

e13608Background: The Spanish Lung Cancer Group (GECP) initiated a Tumor Thoracic Register (RTT) in September 2016 with the aim of evaluating accurate, basic data concerning this oncological pathol...

Komplementāras terapijas lietošana pacientiem, kas saņem pretvēža ārstēšanu - biežums, anamnēzes dokumentācija, un iespējamā mijiedarbība ar terapiju

2015

Ievads Pētījuma mērķis bija komplementārās un alternatīvās medicīnas (KAM) pielietošanas analīze plaušu vēža pacientu vidū, kas saņem standarta pretvēža terapiju; izvērtēt, kāds KAM veids ir vispopulārākais, kāda ir pacientu motivācija to izmantot, kā arī novērtēt ar KAM saistītās priekšrocības, toksicitātes un riskus. Metodes Pētījumā tika iekļauti izplatīta sīkšūnu un ne-sīkšūnu plaušu vēža pacienti, kas saņem paliatīvu ķīmijterapiju un/vai staru terapiju Paula Stradiņa Klīniskās Universitātes Slimnīcas Onkoloģijas klīnikā (Rīga). Dalībniekiem tika piedāvāta aprakstoša anketa latviešu un krievu valodās. Atbilžu precizēšanai tika izmantotas pus-strukturētas intervijas. Dati par toksicitāti…

Spacers and Valved Holding Chambers—The Risk of Switching to Different Chambers

2020

© 2020 The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

Commentaries on Viewpoint: Airway smooth muscle and airway hyperresponsiveness in human asthma: have we chased the wrong horse?

2014

More Relevant Today Than Ever: Past, Present and Future of Media Performance Research

2020

Media performance is constitutive for functioning democracies. But what is the situation regarding media performance in the age of digitalisation? And how can media performance continue to be assured under the current difficult economic conditions for the news industry? In this essay, we give a short overview of how media performance research has developed from the introduction of private broadcasting to the spread of the Internet and social media. In the course of this development, the initial focus of media performance research on media content has broadened to include media quality from the user perspective. We show how the contributions to this thematic issue relate with existing lines …

Demokratie und Gemeinschaft. Oder: wie kontrovers ist die Kommunitarismusdebatte?

1996

"Unter dem Etikett der 'Kommunitarismusdebatte' wird seit einigen Jahren der Umgang mit Differenz und die Integration unterschiedlicher Bevölkerungsgruppen in ein demokratisches politisches System kontrovers diskutiert. Der Streit zwischen 'Kommunitaristen' und 'Liberalen' entzündet sich üaber die Grundlagen der modernen Demokratie. Vereinfacht gründet sich für die Kommunitaristen Demokratie zuerst auf Gemeinschaft und für die Liberalen zuerst auf Gerechtigkeit. Die Kommunitarismusdebatte blieb trotz einer großen Zahl von Beiträgen auf die Analyse moderner westlicher Demokratien beschränkt und sie weist zudem ein 'soziologisches Defizit' auf. Auf diese Lücken zielt meine Fragestellung. Wie …