Search results for "MELD"
showing 8 items of 18 documents
Synthesis of pyrido[2,3-d]pyrimidinones by the reaction of aminopyrimidin-4-ones with benzylidene meldrum's acid derivatives
1997
A series of pyrido[2,3-d]pyrimidine-4,7-diones 5a-h were prepared from 6-amino-4-pyrimidones 1 and benzylidene Meldrum's acid derivatives 2 by cyclization reactions in boiling nitrobenzene. The structure of 5, determined by nmr measurements, reveals a selective orientation of 1 and 2 in the addition step.
ChemInform Abstract: Synthesis of Pyrido(2,3-d)pyrimidinones by the Reaction of Aminopyrimidin-4-ones with Benzylidene Meldrum′s Acid Derivatives.
2010
A series of pyrido[2,3-d]pyrimidine-4,7-diones 5a-h were prepared from 6-amino-4-pyrimidones 1 and benzylidene Meldrum's acid derivatives 2 by cyclization reactions in boiling nitrobenzene. The structure of 5, determined by nmr measurements, reveals a selective orientation of 1 and 2 in the addition step.
Alma Mater: 2014/ Vasara
2014
Andra Čudare. Studentu taisnības bruņinieks Kirils Solovjovs -- Katrīna Žukova. Zinību lauks – atmiņu laiks -- LU māju noslēpumi atklājās Muzeju naktī -- LU Preses centrs. Zinātne – tas ir forši un radoši -- Sarmīte Rutkovska. Futbols kā tikšanās vieta -- LU Zinātnes un tehnikas vēstures muzejs, LU Preses centrs. Fotostāsts. Studentu mode cauri laikiem -- Laine Dobulāne. Atjauno modernākās ērģeles Latvijā -- LU Preses centrs. Praktiķi dalās pieredzē ar topošajiem kolēģiem -- LU Preses centrs. Reportāža. Psihiskas performances un «Ātrā palīdzība» jauno grupu konkursā «Hadrons» -- LU Bibliotēka. Ciparojot šodienai un nākotnei: LU Bibliotēkas pieredze digitalizācijā -- Kārlis Dārznieks. Jau 85…
Zvaigžņotā Debess: 2017/18, Ziema (238)
2017
Contents: “ZVAIGŽŅOTĀ DEBESS” FORTY YEARS AGO: I.Vilka. Starry Sky and Birds’ Journeys (abridged) ; N.Cimahoviča. Spirals of Saturn’s Rings (abridged) ; I.Šmelds. V Readings of Friedrich Zander ; DEVELOPMENTS in SCIENCE: K.Schwartz. Most Distant Galaxy Clusters and 3D Structure of the Universe ; DISCOVERIES: M.Gills. The Day when Multi-Messenger Astronomy Was Announced ; I.Pundure. ESO Telescopes and Hubble Observe the Source of Gravitational Waves for the First Time ; I.Eglītis. Asteroid “Balklavs” ; SPACE RESEARCH and EXPLORATION: R.Misa. Mission of Cassini – Discoveries to the Very End ; J.Jaunbergs. The Icy World Tethys ; OBSERVATORIES and INSTRUMENTS: M.Gills. The Giant Radio Telescope…
5-Carbonyl-1,3-oxazine-2,4-diones from N-Cyanosulfoximines and Meldrum’s Acid Derivatives
2020
At elevated temperatures, N-cyanosulfoximines react with Meldrum's acid derivatives to give sulfoximines with N-bound 5-carbonyl-1,3-oxazine-2,4-dione groups. A representative product was characterized by single-crystal X-ray structure analysis. The product formation involves an unexpected molecular reorientation requiring several sequential bond-forming and -cleaving processes.
Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation.
2014
Abstract Aims Trimethylamine-N-oxide (TMAO) is produced in host liver from trimethylamine (TMA). TMAO and TMA share common dietary quaternary amine precursors, carnitine and choline, which are metabolized by the intestinal microbiota. TMAO recently has been linked to the pathogenesis of atherosclerosis and severity of cardiovascular diseases. We examined the effects of anti-atherosclerotic compound meldonium, an aza-analogue of carnitine bioprecursor gamma-butyrobetaine (GBB), on the availability of TMA and TMAO. Main methods Wistar rats received L-carnitine, GBB or choline alone or in combination with meldonium. Plasma, urine and rat small intestine perfusate samples were assayed for L-car…
Zvaigžņotā Debess: 2008, Vasara
2008
Latvijas Zinātņu akadēmija, Latvijas Universitāte
Child-Pugh Class and Not Thrombocytopenia Impacts the Risk of Complications of Endoscopic Band Ligation in Patients with Cirrhosis and High Risk Vari…
2023
Background and Aims: Endoscopic band legation (EBL) is an effective method for the prophylaxis of acute variceal bleeding (AVB). This procedure may be associated with several complications, particularly bleeding. Our analysis aimed to evaluate the risk of complications due to EBL in a cohort of patients who underwent EBL for the prophylaxis of variceal bleeding and the eventual presence of risk predictors. Patients and Methods: We retrospectively analysed data from consecutive patients who underwent EBL in a primary prophylaxis regimen. For all patients, simultaneously with EBL, we recorded the Child–Pugh and MELD score, platelet count and US features of portal hypertension. Results: We col…