Search results for "MOLECULE"

Synthesis of a new family of bi- and polycyclic compounds via Pd-catalyzed amination of 1,7-di(3-bromobenzyl)cyclen

2008

Abstract New bicyclic cryptand type compounds are synthesized by reacting 1,7-di(3-bromobenzyl)cyclen with 1 equiv of linear polyamines under dilute conditions using Pd-catalyzed amination. Bis(cyclen) and tris(cyclen) compounds containing linear polyamine linkers between benzylated cyclens are obtained by a similar procedure using different reaction conditions. Cyclization of these species via intramolecular catalytic diamination led to tri- and tetracyclic polyaza compounds.

Combination of single-molecule magnet behaviour and luminescence properties in a new series of lanthanide complexes with tris(pyrazolyl)borate and ol…

2020

A series of tris(pyrazolyl)borate mono-, di- and trinuclear complexes, [Tp2Ln]nX (Ln = Eu, Tb, Gd, Dy, Xn− = various mono-, bis- and tris(β-diketonates) has been prepared. The Tb3+ and Dy3+ complexes are luminescent single molecular magnets (SMM) and exhibit luminescence quantum efficiencies up to 73% for the Tb3+ and 4.4% for the Dy3+ compounds. Similar Eu3+ complexes display bright emission only at lower temperatures. The Dy3+ and Tb3+ complexes possess SMM behavior in a non-zero dc field at low temperatures, while the polynuclear Dy3+ complexes also show slow magnetic relaxation even in zero dc field up to 8 K. Ueff-values determined from dynamic magnetic measurements were up to 31 and 6…

Orthometalation of Tris(3-sodium sulfonatophenyl)phosphine with Dirhodium(II) Acetate

1998

Tetraacetatodirhodium(II) reacts with tris(3-sodium sulfonatophenyl)phosphine (TPPTS) giving [Rh2(μ-OOCCH3)3{μ-(3-NaO3SC6H3)P(C6H4SO3Na-3)2}(HOOCCH3)]·6H2O (1) and [Rh2(μ-OOCCH3)2{μ-(3-NaO3SC6H3)P(C6H4SO3Na-3)2}2(HOOCCH3)]·12H2O (2). Their structures and properties have been studied by electronic, IR, and 31P{1H}, 1H, 1H{31P}, and 13C{1H} NMR spectroscopies. In compound 1, one of the acetate bridges is replaced by a phosphine ligand, orthometalated via the C2 carbon atom of the phenyl ring. One axial site of the Rh24+ core is occupied by a sulfonato group of the metalated ring and another one by a labile molecule of acetic acid. 1H NMR spectroscopy shows that chemical shifts of the aromatic…

Darstellung einiger oligomerer Cyclo{oligo[(2-hydroxy-1,3-phenylen)methylen]}e. Spektroskopische Untersuchung ihrer Pseudorotation

1978

Es wird die Darstellung von Cyclo{tris[(2-hydroxy-5-methyl-1,3-phenylen)methylen]-(2-hydroxy-5-tert-butyl-1,3-phenylen)methylen} (4a), Cyclo{bis[(2-hydroxy-5-methyl-1,3-phenylen)methylen]-bis[(2-hydroxy-5-tert-butyl-1,3-phenylen)methylen]}(4b) und Cyclo-{pentakis[(2-hydroxy-5-methyl-1,3-phenylen)methylen]} (4c) beschrieben. Die IR-Spektren zeigen, das die phenolischen Hydroxygruppen der Vierringverbindungen 4a und 4b intramolekulare, vom Losungs(CCl4)- oder Zerteilungsmittel (KBr) weitgehend unabhangige Wasserstoffbrucken bilden, die bei der pentameren Ringverbindung 4c schwacher sind. Anhand der 1H-NMR-Spektren last sich bei diesen Verbindungen eine Pseudorotation nachweisen. Die Massenspe…

Orthometallation reactions of tris(p-methoxyphenyl)phosphine with dirhodium(II) tetraacetate

1998

Abstract Reactions of dirhodium(II)tetraacetate [Rh2(OAc)4] with tris(p-methoxyphenyl)phosphine (PMP) at 1:1 and 1:2 molar ratios yield, first appropriate adducts: [Rh2(OAc)4P(p-CH3OC6H4)3] (1a) and [Rh2(OAc)4{P(p-CH3OC6H4)3}2] (2a), and then orthometallated [Rh2(OAc)3{μ-(p-CH3OC6H3)P(p-CH3OC6H4)2}(HOAc)2] (1) and [Rh2(OAc)2{μ-(p-CH3OC6H3)P(p-CH3OC6H4)2}2(HOAc)2] (2) complexes, respectively. They have been characterized by spectroscopic methods. The molecular structure of 1 has been determined by the X-ray methods. Crystal data: space group P1, a=11.085(5), b=11.387(5), c=13.900(6) A, α=97.29(3), β=105.23(3), γ=91.93(3)°. In this compound The Rh–Rh distance is 2.421(1), Rh–P bond length 2.1…

UV-induced solvent free synthesis of truxillic acid–bile acid conjugates

2009

The solvent free UV-induced [2 + 2] intermolecular cycloaddition of two molecules of 3α-cinnamic acid ester of methyl lithocholate produced in 99% yield of α- and e-truxillic acid-bis(methyl lithocholate) isomers, which possess two structurally different potential binding sites. A prerequisite for this effective solid state reaction is a proper self-assembled crystal structure of the starting conjugate crystallized from acetonitrile. The crystallization of cinnamic acid ester of methyl lithocholate from acetonitrile produces two different crystalline forms (polymorphs), which is the reason for the solid state formation of two isomers of truxillic acid-bis(methyl lithocholate).

Radical salts of TTF derivatives with the metal-metal bonded [Re2Cl8]2- anion

2008

Abstract Four new salts of the radical cations of TMTSF (tetramethyltetraselenafulvalene), TMTTF (tetramethyltetrathiafulvalene), BEDT-TTF (bisethylenedithiotetrathia-fulvalene) (ET) and o-Me2TTF (o-4,4′-dimethyltetrathiafulvalene) with the metal–metal bonded dianion [Re2Cl8]2− were synthesized, and their structures and physical properties investigated. The structures of these semiconducting salts feature one-dimensional stacking of the donor molecules interleaved with [Re2Cl8]2− anions and interstitial solvent molecules.

Longitudinal analysis of Mycobacterium tuberculosis 19-kDa antigen-specific T cells in patients with pulmonary tuberculosis: association with disease…

2003

CD8(+) T cells play a central role in immune protection against infection with Mycobacterium tuberculosis. One of the target epitopes for anti-M. tuberculosis directed CD8(+) T cells is the HLA-A2-restricted 19-kDa lipoprotein peptide VLTDGNPPEV. T cell clones directed against this epitope recognized not only the nominal peptide ligand, but also a closely related peptide (VPTDPNPPEV) from the HIV envelope gp120 (HIV(env) gp120) protein characterized by IFN-gamma release. This cross-reactivity was confirmed in ex vivo in M. tuberculosis 19-kDa tetramer-sorted T cells from patients with tuberculosis and in HIVgp120 tetramer-reactive T cells sorted from HIV(+) patients. M. tuberculosis 19-kDa …

Granzyme A is an additional marker for tuberculosis (TB) to discriminate between patients with active disease and subjects with latent infection.

2013

MMP-10/stromelysin-2 promotes invasion of head and neck cancer.

2011

BackgroundPeriostin, IFN-induced transmembrane protein 1 (IFITM1) and Wingless-type MMTV integration site family, member 5B (Wnt-5b) were previously identified as the invasion promoted genes of head and neck squamous cell carcinoma (HNSCC) by comparing the gene expression profiles between parent and a highly invasive clone. We have previously reported that Periostin and IFITM1 promoted the invasion of HNSCC cells. Here we demonstrated that Wnt-5b overexpression promoted the invasion of HNSCC cells. Moreover, stromelysin-2 (matrix metalloproteinase-10; MMP-10) was identified as a common up-regulated gene among Periostin, IFITM1 and Wnt-5b overexpressing HNSCC cells by using microarray data s…