Search results for "Methods"

showing 10 items of 4526 documents

TAF-ChIP: an ultra-low input approach for genome-wide chromatin immunoprecipitation assay

2019

The authors present a novel method for obtaining chromatin profiles from low cell numbers without prior nuclei isolation. The method is successfully implemented in generating epigenetic profile from 100 cells with high signal-to-noise ratio.

Health Toxicology and MutagenesisPlant ScienceComputational biologySignal-To-Noise RatioBiochemistry Genetics and Molecular Biology (miscellaneous)GenomeDNA sequencingEpigenesis GeneticHistones03 medical and health sciences0302 clinical medicineTranscriptional regulationMethodsAnimalsHumansEpigenetics030304 developmental biologyWhole genome sequencing0303 health sciencesEcologybiologyWhole Genome SequencingChemistryHigh-Throughput Nucleotide SequencingChip11Histonebiology.proteinChromatin Immunoprecipitation SequencingDrosophilaK562 CellsChromatin immunoprecipitation030217 neurology & neurosurgerySoftwareLife Science Alliance
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Chronic toxicity of methylparathion to Daphnia magna: Effects on survival, reproduction, and growth

1995

Health Toxicology and Mutagenesismedia_common.quotation_subjectDaphnia magnaBranchiopodaZoologyMethyl ParathionToxicologyToxicologyToxicity TestsAnimalsEcotoxicologyChronic toxicitymedia_commonAnalysis of VariancebiologyReproductionGeneral Medicinebiology.organism_classificationPollutionInvestigation methodsDaphniaCladoceraToxicityFemalePest ControlReproductionWater Pollutants ChemicalBulletin of Environmental Contamination and Toxicology
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Zoom in on Dry Joy—Dissensus, Agonism and Democracy in Art Education

2021

Literature on art education often emphasizes dialogue as a preferred approach and as a way of practicing democratic education in museums and galleries. Dialogue-based tours in such contexts are often characterized by a sense of harmony and agreement. In contrast, this article discusses the democratic aspect and political potentiality when dissensus and agonism are used as central educational strategies. The point of departure for the discussion was a teaching session on the online platform Zoom with student teachers as part of their module on art and crafts at the University of Agder in Kristiansand, Norway, in spring 2020. Artworks from the exhibition Dry Joy, in S&oslash

HegemonyPublic AdministrationdemocracyTeaching methodmedia_common.quotation_subjectPhysical Therapy Sports Therapy and RehabilitationDemocratic educationVisual arts educationEducationExhibitionPolitics0504 sociologyagonismDevelopmental and Educational PsychologyComputer Science (miscellaneous)AgonismSociologymedia_commonmuseum05 social sciencesMedia studies050401 social sciences methods050301 educationdissensusVDP::Samfunnsvitenskap: 200::Pedagogiske fag: 280DemocracyComputer Science Applicationsart educationonline platformlcsh:L0503 educationlcsh:Education
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Non-alcoholic fatty pancreas disease pathogenesis: a role for developmental programming and altered circadian rhythms.

2013

Objectives Emerging evidence suggests that maternal obesity (MO) predisposes offspring to obesity and the recently described non-alcoholic fatty pancreas disease (NAFPD) but involved mechanisms remain unclear. Using a pathophysiologically relevant murine model, we here investigated a role for the biological clock - molecular core circadian genes (CCG) in the generation of NAFPD. Design Female C57BL6 mice were fed an obesogenic diet (OD) or standard chow (SC) for 6 weeks, prior to pregnancy and throughout gestation and lactation: resulting offspring were subsequently weaned onto either OD (Ob_Ob and Con_Ob) or standard chow (Ob_Con and Con_Con) for 6 months. Biochemical, pro-inflammatory and…

HeredityPhysiologylcsh:MedicineCLOCK ProteinsGene ExpressionMouse ModelsGastroenterology and HepatologyResearch and Analysis MethodsModel OrganismsPregnancyGeneticsMedicine and Health SciencesAnimalsRNA MessengerObesitylcsh:ScienceNutritionAnalysis of Variancelcsh:RBody WeightGene Expression Regulation DevelopmentalPancreatic DiseasesBiology and Life SciencesAnimal ModelsCircadian RhythmMice Inbred C57BLPhysiological ParametersPrenatal Exposure Delayed Effectslcsh:QFemaleEpigeneticsAnatomyPhysiological ProcessesDigestive SystemChronobiologyResearch ArticlePloS one
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Electron-density critical points analysis and catastrophe theory to forecast structure instability in periodic solids

2018

The critical points analysis of electron density,i.e. ρ(x), fromab initiocalculations is used in combination with the catastrophe theory to show a correlation between ρ(x) topology and the appearance of instability that may lead to transformations of crystal structures, as a function of pressure/temperature. In particular, this study focuses on the evolution of coalescing non-degenerate critical points,i.e. such that ∇ρ(xc) = 0 and λ1, λ2, λ3≠ 0 [λ being the eigenvalues of the Hessian of ρ(x) atxc], towards degenerate critical points,i.e. ∇ρ(xc) = 0 and at least one λ equal to zero. The catastrophe theory formalism provides a mathematical tool to model ρ(x) in the neighbourhood ofxcand allo…

Hessian matrixElectron densitycatastrophe theory010504 meteorology & atmospheric sciencesCondensed Matter Physic010502 geochemistry & geophysics01 natural sciencesBiochemistryInstabilityInorganic Chemistrysymbols.namesakeStructural BiologyAb initio quantum chemistry methodsGeneral Materials Sciencephase/state transitions in crystalPhysical and Theoretical Chemistryphase/state transitions in crystalsEigenvalues and eigenvectors0105 earth and related environmental sciencesPhysicsab initio calculationelectron-density critical pointCondensed matter physicsab initio calculationsDegenerate energy levelsCondensed Matter PhysicsGibbs free energyelectron-density critical points catastrophe theory phase/state transitions in crystals ab initio calculations.symbolsMaterials Science (all)Catastrophe theoryelectron-density critical points
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Bayesian PDF reweighting meets the Hessian methods

2016

Volume: 273 New data coming from the LHC experiments have a potential to extend the current knowledge of parton distribution functions (PDFs). As a short cut to the cumbersome and time consuming task of performing a new PDF fit, re weighting methods have been proposed. In this talk, we introduce the so-called Hessian re-weighting, valid for PDF fits that carried out a Hessian error analysis, and compare it with the better-known Bayesian methods. We determine the existence of an agreement between the two approaches, and illustrate this using the inclusive jet production at the LHC. Peer reviewed

Hessian matrixPhysicsNuclear and High Energy PhysicsParticle physicsLarge Hadron Colliderta114parton distribution functionsJet (mathematics)010308 nuclear & particles physicsBayesian probabilityPartonJET DATAre-weighting methodsPROTON114 Physical sciences01 natural sciencesBayesian re-weightingsymbols.namesakeError analysisPARTON DISTRIBUTIONS0103 physical sciencessymbolsLHCHessian re-weighting010306 general physicsNuclear and Particle Physics Proceedings
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PDF reweighting in the Hessian matrix approach

2014

We introduce the Hessian reweighting of parton distribution functions (PDFs). Similarly to the better-known Bayesian methods, its purpose is to address the compatibility of new data and the quantitative modifications they induce within an existing set of PDFs. By construction, the method discussed here applies to the PDF fits that carried out a Hessian error analysis using a non-zero tolerance $\Delta\chi^2$. The principle is validated by considering a simple, transparent example. We are also able to establish an agreement with the Bayesian technique provided that the tolerance criterion is appropriately accounted for and that a purely exponential Bayesian likelihood is assumed. As a practi…

Hessian matrixPhysicsParticle physicsNuclear and High Energy PhysicsStatistical methodsta114Bayesian probabilityFOS: Physical sciencesPartonQCDExponential functionHigh Energy Physics - Experimentsymbols.namesakeHigh Energy Physics - PhenomenologyHigh Energy Physics - Experiment (hep-ex)Distribution functionHigh Energy Physics - Phenomenology (hep-ph)Error analysissymbolsParton modelApplied mathematicsJournal of High Energy Physics
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On the peculiar long-term orbital evolution of the eclipsing accreting millisecond X-ray pulsar SWIFT J1749.4-2807

2022

We present the pulsar timing analysis of the accreting millisecond X-ray pulsar SWIFT J1749.4-2807 monitored by NICER and XMM-Newton during its latest outburst after almost eleven years of quiescence. From the coherent timing analysis of the pulse profiles, we updated the orbital ephemerides of the system. Large phase jumps of the fundamental frequency phase of the signal are visible during the outburst, consistent with what was observed during the previous outburst. Moreover, we report on the marginally significant evidence for non-zero eccentricity ($e\simeq 4\times 10^{-5}$) obtained independently from the analysis of both the 2021 and 2010 outbursts and we discuss possible compatible sc…

High Energy Astrophysical Phenomena (astro-ph.HE)Accretiongeneral [Binaries]Astrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesneutron [Stars]Astronomy and Astrophysicsstars: neutronX-rays: binariesSettore FIS/05 - Astronomia E Astrofisicabinaries: generalSpace and Planetary Scienceaccretion accretion discsbinaries [X-rays][PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det][PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]Astrophysics - High Energy Astrophysical PhenomenaAstrophysics - Instrumentation and Methods for AstrophysicsInstrumentation and Methods for Astrophysics (astro-ph.IM)Accretion discs
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Recent GRBs observed with the 1.23m CAHA telescope and the status of its upgrade

2010

We report on optical observations of Gamma-Ray Bursts (GRBs) followed up by our collaboration with the 1.23m telescope located at the Calar Alto observatory. The 1.23m telescope is an old facility, currently undergoing upgrades to enable fully autonomous response to GRB alerts. We discuss the current status of the control system upgrade of the 1.23m telescope. The upgrade is being done by our group based on the Remote Telescope System, 2nd Version (RTS2), which controls the available instruments and interacts with the EPICS database of Calar Alto. (Our group is called ARAE (Robotic Astronomy & High-Energy Astrophysics) and is based on members of IAA (Instituto de Astrofísica de Andalucía). …

High Energy Astrophysical Phenomena (astro-ph.HE)Article Subjectlcsh:AstronomyComputer scienceAstronomyFOS: Physical sciencesAstronomy and AstrophysicsBOOTESlaw.inventionlcsh:QB1-991TelescopeUpgradeSpace and Planetary ScienceObservatorylawAstrophysics - Instrumentation and Methods for AstrophysicsAstrophysics - High Energy Astrophysical PhenomenaGamma-ray burstInstrumentation and Methods for Astrophysics (astro-ph.IM)
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Partial stellar tidal disruption events and their rates

2023

Tidal disruption events (TDEs) of stars operated by massive black holes (MBHs) will be detected in thousands by upcoming facilities such as the Vera Rubin Observatory. In this work, we assess the rates of standard total TDEs, destroying the entire star, and partial TDEs, in which a stellar remnant survives the interaction, by solving 1-D Fokker-Planck equations. Our rate estimates are based on a novel definition of the loss cone whose size is commensurate to the largest radius at which partial disruptions can occur, as motivated by relativistic hydrodynamical simulations. Our novel approach unveils two important results. First, partial TDEs can be more abundant than total disruptions by a f…

High Energy Astrophysical Phenomena (astro-ph.HE)Astrophysics - Solar and Stellar AstrophysicsAstrophysics of Galaxies (astro-ph.GA)FOS: Physical sciencesAstrophysics - High Energy Astrophysical PhenomenaAstrophysics - Instrumentation and Methods for Astrophysics85A05Instrumentation and Methods for Astrophysics (astro-ph.IM)Astrophysics - Astrophysics of GalaxiesSolar and Stellar Astrophysics (astro-ph.SR)
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